口腔精准仿生修复技术的自主创新研发与转化  

Independent innovation research,development and transformation of precise bionic repair technology for oral prosthesis

作　　者：孙玉春[1] 郭雨晴 陈虎[1] 邓珂慧[1] 李伟伟[1] SUN Yu-chun;GUO Yu-qing;CHEN Hu;DENG Ke-hui;LI Wei-wei(Center of Digital Dentistry, Faculty of Prosthodontics, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health & NMPA Key Laboratory for Dental Materials, Beijing 100081, China)

机构地区：[1]北京大学口腔医学院·口腔医院口腔医学数字化研究中心,口腔修复教研室,国家口腔医学中心,国家口腔疾病临床医学研究中心,口腔数字化医疗技术和材料国家工程实验室,口腔数字医学北京市重点实验室,国家卫生健康委员会口腔医学计算机应用工程技术研究中心,国家药品监督管理局口腔材料重点实验室,北京100081

出　　处：《北京大学学报（医学版）》2022年第1期7-12,共6页Journal of Peking University:Health Sciences

基　　金：国家自然科学基金(81271181、51475004、52035001);国家重点研发计划项目(2019YFB1706900);首都科技领军人才培养工程(Z191100006119022)。

摘　　要：根据《第四次全国口腔健康流行病学调查报告》(2018),我国各年龄组缺损、缺失牙齿达数十亿颗。牙齿缺损、缺失后会导致咀嚼功能障碍、营养摄入障碍,易导致颞下颌关节疾病甚至诱发心血管疾病等全身系统性疾病,需及时用口腔修复体重建生理功能。口腔数字化修复技术在口腔医学领域的应用主要包括三维扫描、计算机辅助设计(computer aided design,CAD)、计算机辅助制造(computer aided manufacturing,CAM)、可数字化加工的材料等[1],能显著提高口腔修复的效率与精度。According to the fourth national oral health epidemiological survey report(2018),billions of teeth are lost or missing in China,inducing chewing dysfunction,which is necessary to build physiological function using restorations.Digital technology improves the efficiency and accuracy of oral restoration,with the application of three-dimensional scans,computer-aided design(CAD),computer-aided manufacturing(CAM),bionic material design and so on.However,the basic research and product development of digital technology in China lack international competitiveness,with related products basically relying on imports,including denture 3D design software,3D oral printers,and digitally processed materials.To overcome these difficulties,from 2001,Yuchun Sun’s team,from Peking University School and Hospital of Stomatology,developed a series of studies in artificial intelligence design and precision bionics manufacturing of complex oral prostheses.The research included artificial intelligence design technology for complex oral prostheses,3D printing systems for oral medicine,biomimetic laminated zirconia materials and innovative application of digital prosthetics in clinical practice.The research from 2001 to 2007 was completed under the guidance of Prof.Peijun Lv and Prof.Yong Wang.Under the support of the National Natural Science Foundation of China,the National Science and Technology Support Program,National High-Tech R&D Program(863 Program)and Beijing Training Project for the Leading Talents in S&T,Yuchun Sun’s team published over 200 papers in the relevant field,authorized 49 national invention patents and 1 U.S.invention patent and issued 2 national standards.It also developed 8 kinds of core technology products in digital oral prostheses and 3 kinds of clinical diagnosis and treatment programs,which significantly improved the design efficiency of complex oral prostheses,the fabrication accuracy of metal prostheses and the bionic performance of ceramic materials.Compared with similar international technologies,the prog

关 键 词：人工智能 3D打印 数字化技术 口腔修复体 仿生材料 

分 类 号：R783.4[医药卫生—口腔医学]