0.3%苦皮藤素水乳剂的制备及生物活性研究  

Study on the Preparation and Bioactivity of Celangulin 0.3%EW

作　　者：王秦 胡航 龚顺泽 徐德锋[1] WANG Qin;HU Hang;GONG Shunze;XU Defeng(School of Pharmacy,Changzhou University,Jiangsu Changzhou213164,China)

机构地区：[1]常州大学药学院,江苏常州213164

出　　处：《现代农药》2022年第1期30-34,46,共6页MODERN AGROCHEMICALS

基　　金：江苏省“双创计划”—双创团队项目(苏人才办[2017]37号)。

摘　　要：本研究确定了0.3%苦皮藤素水乳剂的稳定配方,并对其防效进行测试。采用相转移法制备0.3%苦皮藤素水乳剂,以外观、液滴平均粒径、Zeta电位等表征方法判断所制备的水乳剂是否稳定。使用喷雾法测定其室内生物活性。0.3%苦皮藤素水乳剂的稳定配方为:苦皮藤素原药1.66%、EL-409.0%、Solvesso15015%、乙二醇4.0%、消泡剂0.1%、增稠剂0.02%,去离子水补足至100%。0.3%苦皮藤素水乳剂各项指标均符合水乳剂产品要求,其500倍液对玉米象有较高的室内生物活性,施药7 d后防效为90%,高于10%氰戊菊酯乳油500倍液。This study aimed to determine a stable formula of celangulin 0.3%EW and test its effect.The celangulin 0.3%EW was prepared by the phase inversion method.The stability of emulsion in water was judged by the appearance,average droplet size,and zeta potential etc..The bioactivity was determined by spray method.The stable formula of celangulin 0.3%EW was celangulin original drug 1.66%,EL-409.0%,Solvesso15015%,glycol 4.0%,defoamer 0.1%,thickener 0.02%and deionized water.All the indexes of 0.3%celangulin EW met the requirements,and 500 times of celangulin 0.3%EW had good bioactivity to Sitophilus zeamais.The efficacy of 500 times of celangulin 0.3%EW was 90%at 7 d after treatment,and better than that of 500 times of fenvalerate.

关 键 词：苦皮藤素 氰戊菊酯 水乳剂 乳状液稳定性 生物活性 pH 玉米象 

分 类 号：TQ453.3[化学工程—农药化工] TQ450