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作 者:中华医学会消化病学分会胃肠激素与黏膜屏障学组 李景南[2] Gastrointestinal Hormone and Mucosal Barrier Group,Chinese Society of Gastroenterology,Chinese Medical Association
机构地区:[1]不详 [2]中国医学科学院北京协和医学院北京协和医院消化内科,100730
出 处:《中华消化杂志》2021年第12期798-811,共14页Chinese Journal of Digestion
摘 要:胃肠道黏膜覆盖全胃肠道,具有重要的生理学作用。黏膜屏障与损伤是消化道疾病的共同发病机制,但临床诊断、病因诊断、治疗策略和黏膜保护剂的规范使用等方面仍缺乏深入、系统的认识。本共识基于循证医学证据,在胃黏膜屏障与防护的概念、生理作用、胃肠道黏膜损伤与相关疾病的发生机制、黏膜保护剂的分类和合理应用方面达成共识,旨在为胃肠道黏膜保护的临床应用提供依据。The gastrointestinal mucosa covers the entire gastrointestinal tract.With important physiological functions,the injuries of mucosal barrier are the common pathogenesis of gastrointestinal diseases.However,there still lacks in-depth and systematic understanding in clinical diagnosis,etiological diagnosis,treatment strategies and the standardized use of mucosal protective agents.Based on medicine-based evidence,this consensus has reached an agreement on the concept of gastric mucosal barrier and protection,physiological functions,gastrointestinal mucosal injury and related diseases,and the classification and application of mucosal protective agents.The consensus provides an significant reference for clinical treatment of gastrointestinal mucosal protection.
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