肌层浸润性膀胱癌根治术患者的预后影响因素分析  

Prognostic Factors After Radical Resection in Patients with Myometrial Invasive Bladder Cancer

作　　者：王秋红[1] 左书强[1] 刘坤龙 齐艳[1] WANG Qiuhong;ZUO Shuqiang;LIU Kunlong(The First Affiliated Hospital of Zhengzhou University,Zhengzhou,450000)

机构地区：[1]郑州大学第一附属医院,450000

出　　处：《实用癌症杂志》2022年第1期111-113,共3页The Practical Journal of Cancer

摘　　要：目的分析肌层浸润性膀胱癌根治术患者的预后影响因素。方法选取肌层浸润性膀胱癌患者71例,统计1年生存率,收集患者年龄、性别、肿瘤直径等信息,分析预后影响因素。结果本组71例患者,1年生存率为88.73%(63/71)。肿瘤直径、肿瘤数量、有无淋巴结转移、有无术前新辅助化疗、有无术后辅助放化疗是肌层浸润性膀胱癌患者术后1年生存的影响因素(P<0.05);logistic回归分析显示,肿瘤直径>3 cm、淋巴结转移、肿瘤多发是患者术后1年生存的危险因素,术前新辅助化疗、术后辅助放化疗是术后1年生存的保护因素(P<0.05)。结论肿瘤直径>3 cm、淋巴结转移、肿瘤多发是患者术后1年生存的危险因素,术前新辅助化疗、术后辅助放化疗是术后1年生存的保护因素,临床在采用根治术治疗肌层浸润性膀胱癌时可据此实施防控措施,以进一步提高手术效果。Objective To analyze the prognostic factors of radical resection of myometrial invasive bladder cancer.Methods 71 patients with myometrial invasive bladder cancer were selected,1-year survival rate,age,gender,tumor diameter were collected,the prognostic factors were analyzed.Results Of the 71 patients,1-year survival rate was 88.73 per cent(63/71);Tumor diameter,tumor number,lymph node metastasis,preoperative neoadjuvant chemotherapy,postoperative adjuvant radiotherapy and chemotherapy were the influencing factors of survival in patients with myometrial invasive bladder cancer(P<0.05);logistic regression analysis showed,Tumor diameter>3 cm、lymph node metastasis and multiple tumors were the risk factors for 1-year survival after operation,preoperative neoadjuvant chemotherapy and postoperative adjuvant radiotherapy and chemotherapy were protective factors for survival one year after operation(P<0.05).Conclusion Tumor diameter>3 cm、lymph node metastasis and multiple tumors are the risk factors for 1-year survival,preoperative neoadjuvant chemotherapy and postoperative adjuvant radiotherapy and chemotherapy are the protective factors for 1-year survival after operation,In the treatment of myometrial invasive bladder cancer,Control measures can be implemented accordingly,In order to further improve the effect of surgery.

关 键 词：肌层浸润性膀胱癌 根治术 预后 影响因素 

分 类 号：R737.14[医药卫生—肿瘤]