Study on the Forming Process of Yi Medicine Tongfeng Granules  

作　　者：Xuelian ZHAO Yisong LI Ling TAN Hongna SU Junzhang QUBIE Wenbing LI Yuan LIU 

机构地区：[1]Pharmacy College, Southwest Minzu University, Chengdu 610041, China [2]Sichuan Provincial Qiang-Yi Medicinal Resources Protection and Utilization Technology Engineering Laboratory, Chengdu 610225, China [3]Key Laboratory of Tibetan Plateau Ethnic Medicinal Resources Protection and Utilization of National Ethnic Affairs Commission of the People's Republic of China, Chengdu 610225, China [4]Institute of Qinghai-tibetan Plateau, Southwest Minzu University, Chengdu 610041, China [5]Ethnic Medicine Institute, Southwest Minzu University, Chengdu 610041, China

出　　处：《Medicinal Plant》2021年第6期37-39,43,共4页药用植物：英文版

基　　金：National Key R&D Program(2018YFC1708005);Sichuan Provincial Key R&D Project(2021YFS0043);Fundamental Research Funds for the Central Universities(2020NGD01).

摘　　要：[Objectives]To optimize the forming process of Yi medicine Tongfeng Granules.[Methods]The forming process of Yi medicine Tongfeng Granules was optimized,with paste density,ethanol volume fraction,and type and proportion of excipient as influencing factors,and granule formability,solubility,moisture absorption,and angle of repose as evaluation indicators.Critical relative humidity(CRH)was investigated to select optimal storage conditions.[Results]Maltodextrin was selected as the excipient,and the best process parameters was the ratio of drug to excipient at 1∶2(g/g),under which the forming rate,solubility,moisture absorption rate,and angle of repose were 81.38%,98.90%,8.81%,and 27.5°,respectively.The critical relative humidity was 72%.[Conclusions]The forming process adopted is reasonable and feasible,and can provide a reference for large-scale production of Yi medicine Tongfeng Granules.

关 键 词：Yi medicine Tongfeng Granules EXCIPIENT Forming process Critical relative humidity 

分 类 号：TG1[金属学及工艺—金属学]