EXCIPIENT

作品数：25被引量：29H指数：3
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相关领域：医药卫生更多>>
相关作者：王雪王家鑫牛佳汪宇更多>>
相关机构：安捷伦科技(中国)有限公司江苏省食品药品监督检验研究院南京威尔药业集团股份有限公司南京中医药大学更多>>
相关期刊：《Chemical Research in Chinese Universities》《World Journal of Radiology》《Asian Journal of Pharmaceutical Sciences》《World Journal of Clinical Pediatrics》更多>>
相关基金：国家自然科学基金中国博士后科学基金北京市自然科学基金国家重点基础研究发展计划更多>>
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Synthesis of a novel pharmaceutical excipient: An anion exchange resin
《Journal of Chinese Pharmaceutical Sciences》2025年第2期109-125,共17页Zhannuan Yin Xianghuan Meng Yingshu Feng Ke Li Xinyi Tang Hongfei Liu Haibing He Wei Mi 
2023 Nantong Jianghai Talents Project,the Nantong Social Livelihood Science and Technology Plan for 2023;the 2022 New Drugs and Platform Enhancement Project of the Yangtze Delta Drug Advanced Research Institute.Additionally,support was p rovided by the Zhenjiang Science and Technology Project(Grant No.SH2020048);the China Postdoctoral Science Foundation(Grant No.2020M681532);the Jiangsu Planned Projects for Postdoctoral Research Funds(Grant No.2020Z209);the Natural Science Research Projects of Universities in Jiangsu Province(Grant No.20KJD350001).
The aim of this study was to develop a novel pharmaceutical excipient:an anion exchange resin.Initially,polystyrenedivinylbenzene(PS-DVB)microspheres were synthesized via suspension polymerization.Subsequently,these m...
关键词：Suspension polymerization reaction POLYSTYRENE-DIVINYLBENZENE Quaternarization reaction Anion exchange resin Fluidized bed coating method Pharmacokinetic research 
Azocalixarenes: a scaffold of universal excipients with high efficiency
《Science China Chemistry》2024年第5期1697-1706,共10页Yu-Xin Yue Yi-Lin Lin Meng-Meng Chen Han-Wen Tian Rong Ma Ze-Han Wang Fang-Yuan Chen Yu-Chen Pan Dong-Sheng Guo 
supported by the National Natural Science Foundation of China (U20A20259, 22201141);the Fundamental Research Funds for the Central Universities;the NCC Fund(NCC2020FH04);the China Postdoctoral Science Foundation(2022M711697)。
Excipients are important components of pharmaceutical preparations that affect their quality, safety, and efficacy. Macrocyclic receptors are a family of supramolecular excipients with several advantages, including mo...
关键词：supramolecular chemistry host-guest systems EXCIPIENT CALIXARENE molecular recognition 
Excipient effect on antimicrobial activity of Cinnamon (Cinnamomum zelylanicum album) oil, Thyme (Thymus vulgaris) oil and Ajowan (Trachyspermum ammi) oil
《Infectious Diseases Research》2024年第1期27-31,共5页Bhoj R Singh Shiv Varan Singh Ravikant Agarwal Akanksha Yadav 
supported by grants received from CAAST-ACLH(NAHEP/CAAST/2018-19)of ICAR-World Bank-funded National Agricultural Higher Education Project(NAHEP).
Background:Many herbal essential oils are potential antimicrobials but their pharmaceutical utility is restricted due to a lack of suitable excipients to mollify their dermatotoxicity and irritant property,and outcome...
关键词：essential oils herbal antimicrobials herbal drug-resistance Bacteria Candida 
Nano-enabled agglomerates and compact:Design aspects of challenges
《Asian Journal of Pharmaceutical Sciences》2023年第2期28-48,共21页Nazurah Binti Sazali Lai Wah Chan Tin Wui Wong 
Nanoscale medicine confers passive and active targeting potential.The development of nanomedicine is however met with processing,handling and administration hurdles.Excessive solid nanoparticle aggregation and caking ...
关键词：AGGLOMERATION COMPACTION EXCIPIENT NANOMEDICINE NANOSTRUCTURE 
Effects of polyol excipient stability during storage and use on the quality of biopharmaceutical formulations被引量：1
《Journal of Pharmaceutical Analysis》2022年第5期774-782,共9页Min-Fei Sun Jia-Ning Liao Zhen-Yi Jing Han Gao Bin-Bin Shen You-Fu Xu Wei-Jie Fang 
generously provided by the National Natural Science Foundation of China(Grant No.:81741144);Ministry of Science and Technology of China(Grant No.:2018ZX09J18107-002).
Biopharmaceuticals are formulated using a variety of excipients to maintain their storage stability.However,some excipients are prone to degradation during repeated use and/or improper storage,and the impurities gener...
关键词：Excipient stability GC-MS GLYCEROL LC-MS/MS MANNITOL THYMOPENTIN 
一种快速分析聚山梨酯80组分的方法被引量：3
《中国药科大学学报》2022年第2期192-199,共8页周颖 赵恂 胡楠 王保成 袁耀佐 
由于聚山梨酯80的组分复杂,分析耗时耗力,亟需寻找一种能够快速分析聚山梨酯80组分的方法。本研究采用ExcipientProfiler药用辅料智能分析系统,通过UHPLC-HRMS对收集到的国内外3家企业共10批样品进行分析,同时利用扩展数据库对分析结果...
关键词：聚山梨酯80 组分分析 ExcipientProfiler软件 数据库 聚类分析 
Study on the Forming Process of Yi Medicine Tongfeng Granules
《Medicinal Plant》2021年第6期37-39,43,共4页Xuelian ZHAO Yisong LI Ling TAN Hongna SU Junzhang QUBIE Wenbing LI Yuan LIU 
National Key R&D Program(2018YFC1708005);Sichuan Provincial Key R&D Project(2021YFS0043);Fundamental Research Funds for the Central Universities(2020NGD01).
[Objectives]To optimize the forming process of Yi medicine Tongfeng Granules.[Methods]The forming process of Yi medicine Tongfeng Granules was optimized,with paste density,ethanol volume fraction,and type and proporti...
关键词：Yi medicine Tongfeng Granules EXCIPIENT Forming process Critical relative humidity 
Biomimetic Recognition of Organic Drug Molecules in Water by Amide Naphthotubes被引量：1
《CCS Chemistry》2021年第4期1078-1092,共15页Yan-Long Ma Mao Quan Xiu-Lian Lin Qian Cheng Huan Yao Xi-Ran Yang Ming-Shuang Li Wei-Er Liu Lin-Ming Bai Ruibing Wang Wei Jiang 
This research was financially supported by the National Natural Science Foundation of China(nos.21772083 and 21822104);the Shenzhen Special Funds(KQJSCX20170728162528382 and JCYJ20180504165810828);the Guangdong Provincial Key Laboratory of Catalysis(2020B121201002);the China Postdoctoral Science Foundation(grant no.2019M652183);the University of Macao(MYRG2019-00059-ICMS);the Shenzhen Nobel Prize Scientists Laboratory Project(C17213101)。
Molecular recognition in water is the basis of numerous biological functions.The key for efficient and selective recognition of an organic drug molecule is to bind both its polar and nonpolar groups.This is achieved b...
关键词：molecular recognition drug excipient supramolecular chemistry Β-CYCLODEXTRIN uril 
Excipient-free porphyrin/SN-38 based nanotheranostics for drug delivery and cell imaging
《Nano Research》2020年第2期503-510,共8页Ye Yuan Ruonan Bo Di Jing Zhao Ma Zhongling Wang Tzu-yin Lin Lijie Dong Xiangdong Xue Yuanpei Li 
The authors gratefully acknowledge the support from Dr.Lis faculty startup funds at UC Davis and Dr.Xues National Natural Science Foundation of China(NSFC)(No.81803002).
Nanotheranostics with comprehensive diagnostic and therapeutic capabilities show exciting cancer treatment potentials.Here,we develop an excipient-free drug delivery system for cancer diagnosis as well as therapy,in w...
关键词：PORPHYRIN 7-ethyl-10-hydroxy-camptothecin(SN-38) drug delivery self-indication nanotheranostics photodynamic therapy 
Succinylated whey protein isolate as a sustained-release excipient of puerarin derivative oral tablets:Preparation,optimization and pharmacokinetics被引量：2
《Asian Journal of Pharmaceutical Sciences》2018年第4期383-394,共12页Rui Zhang Yu Zhang Yue Wu Jun Liu Tiantian Ye Shujun Wang 
This work was done to investigate succinylated commercial whey protein isolate(S-WPI)as an oral sustained-release delivery carrier for puerarin 5(PR-5). The succinylation condi-tions were established for S-WPIs by opt...
关键词：WHEY protein isolate SUCCINYLATION PUERARIN 5 Sustained drug delivery PHARMACOKINETICS 
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