PUERARIN

作品数：117被引量：709H指数：15
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相关领域：医药卫生更多>>
相关作者：陶师祝宇铭杨月欣王竹骆蓉更多>>
相关机构：中国药科大学中国疾病预防控制中心黑龙江中医药大学中南大学湘雅二医院更多>>
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Retraction:Puerarin inhibits proliferation and induces apoptosis by upregulation of miR-16 in bladder cancer cell line T24
《Oncology Research》2025年第4期993-993,共1页Oncology Research Editorial Office 
The published article titled“Puerarin inhibits proliferation and induces apoptosis by upregulation of miR-16 in bladder cancer cell line T24”has been retracted from Oncology Research,Vol.26,No.8,2018,pp.1227–1234.
关键词：PUERARIN bladder cancer bladder cancer cell line T miR APOPTOSIS PROLIFERATION 
Puerarin modulation of CENPA affects downstream PLK1 and CCNB1 expression to inhibit bladder cancer cell proliferation
《Traditional Medicine Research》2024年第9期32-41,共10页Hao Xu Wen Gao Deng Pan Yu-Yang Ma Ruo-Ran Zhang Yong-Li Cao Yu-Chuan Zhou Ming-Yu Xu Pei-Yong Zhang Kun Pang 
supported by National Natural Science Fund Item Number(82004110);Xuzhou Science and Technology Plan Project(KC22096);China Postdoctoral Science Foundation(2022M722674);Xuzhou Medical Reserve Talents Project(XWRCHT20220009);the Xuzhou Clinical Medicine Expert Team Project(2018TD004);Peixian Science and Technology Program(P202410)。
Background:The treatment alternatives for bladder cancer(BLCA),the 10th most prevalent cancer in the world,need to be further investigated,and many active substances like Puerarin in herbal medicine were found to be e...
关键词：PUERARIN BLCA Tandem Mass Tags cell cycle 
Puerarin mediated miR-30b-5p targeting fibroblast activation protein against oral submucous fibrosis
《BIOCELL》2024年第4期591-599,共9页SAIFEI XIE HUI XIE JINCAI GUO JIN TAN YULIN YU MINYI ZHANG SHANG WEN 
This work was supported by the National Natural Science Foundation of China(Nos.81874496,82374530);the Clinical Medical Technology Innovation Guide Project of Hunan Province(No.2020SK53206);the Natural Science Foundation of Hunan Province(No.2021JJ70062);the Changsha Natural Science Foundation Project(No.kq2014019);the Health Special Fund Research Project of Hunan Province(No.B2020-07);the Clinical Pharmaceutical Research Fund of Hunan Medical Association(No.B202012).
Background:Puerarin(Pue)has been reported to be a natural active ingredient with multiple antifibrotic properties.This work aimed at exploring the function of Pue in oral submucousfibrosis(OSF)treatment.Methods:Human or...
关键词：PUERARIN miR-30b-5p FAP Oral submucous fibrosis 
Puerarin inhibits NHE1 activity by interfering with the p38 pathway and attenuates mitochondrial damage induced by myocardial calcium overload in heart failure rats被引量：3
《Acta Biochimica et Biophysica Sinica》2024年第2期270-279,共10页Guopin Pan Baoyue Cui Mingming Han Laibiao Lin Yinlan Li Ling Wang Shuang Guo Yaling Yin Heqin Zhan Peng Li 
This work was supported by the grants from the National Natural Science Foundation of China(Nos.82271460 and U1804197);the Research Foundation of Henan Province(Nos.202300410308 and HNGD2022067);the National High-End Foreign Expert Recruitment Plan of China(No.G2022026006L);the Research Foundation of Xinxiang Medical University(Nos.XYBSKYZZ505319 and XYBSKYZZ201626).
Previous studies have shown that puerarin plays a key role in protecting humans and animals from cardiovascular diseases.The exact mechanism of the therapeutic effect of puerarin on various cardiovascular diseases(pro...
关键词：PUERARIN p38 pathway NHE1 heart failure TGF-β proinflammatory cytokines 
B-cell lymphoma-2 phosphorylation at Ser70 site-related autophagy mediates puerarin-inhibited the apoptosis of MC3T3-E1 cells during osteoblastogenesis被引量：1
《Journal of Traditional Chinese Medicine》2024年第1期27-34,共8页LI Xi LIN Xiangquan CHEN Dongdong LIU Hui 
Fujian Provincial Natural Science:Exploration of Crisis Warning Values for Intraoperative Electrophysiological Monitoring in High-risk Cervical Spondylosis Patients on the Brink of Paralysis(No.2019J01548);Fujian Provincial Clinical Medical Research Center for First Aid and Rehabilitation in Orthopaedic Trauma:Study on the Treatment of Osteoporosis(No.2020Y2014)。
OBJECTIVE:To explore the relationship between autophagy and apoptosis regulated by puerarin during osteoblastogenesis.METHODS:In this study,the effects of puerarin on the autophagic activity and apoptosis level of ost...
关键词：PUERARIN OSTEOBLASTS AUTOPHAGY APOPTOSIS lymphoma B-CELL 
Puerarin inhibits inflammation and lipid accumulation in alcoholic liver disease through regulating MMP8被引量：1
《Chinese Journal of Natural Medicines》2023年第9期670-681,共12页HU Ying WANG Shuxian WU Lan YANG Kai YANG Fan YANG Junfa HU Shuang YAO Yan XIA Xun LIU Yixin PENG Li WAN Jihong SHEN Chuanpu XU Tao 
the National Natural Science Foundation of China(No.31900285);the Natural Science FoundationofAnhuiProvince(Nos.2108085QH309and 2208085MH203);Anhui Medical University"Three Complete Education"Comprehensive Reform Pilot Project(No.2021xsqyr05)。
Alcoholic liver disease(ALD)is a growing global health concern,and its early pathogenesis includes steatosis and steatohepatitis.Inhibiting lipid accumulation and inflammation is a crucial step in relieving ALD.Eviden...
关键词：PUERARIN MMP8 Alcoholic liver disease INFLAMMATORY Lipid accumulation 
Effect of puerarin on inflammation and alveolar bone resorption in experimental rats with periodontitis
《Journal of Hainan Medical University》2023年第8期15-19,共5页WAN Ni MO Li-wen ZHAN Le CHEN Hui-ying ZHANG Li 
Hainan Provincial Financial Science and Technology Program Funded Project-Hainan Provincial Key Research and Development Social Development Project 2020(No.ZDYF2020166);Hainan Provincial Financial Science and Technology Program funded project-Hainan Provincial Key Research and Development Social Development Project 2023(No.ZDYF2023SHFZ095)。
Objective:To investigate the effect of puerarin on inflammation and alveolar bone resorption in rats with experimental periodontitis.Methods:Thirty-six 7-week-old Sprague-Dawley rats were randomly divided into three g...
关键词：PUERARIN Experimental periodontitis CYTOKINE Anti-inflammatory effect Bone protection 
Puerarin@Chitosan composite for infected bone repair through mimicking the bio-functions of antimicrobial peptides被引量：7
《Bioactive Materials》2023年第3期520-530,共11页Liping Ouyang Baohui Chen Xingdan Liu Donghui Wang Yang Li Yun Liao Kelvin W.K.Yeung Xuanyong Liu 
National Natural Science Foundation of China(U21A20100,32000938);Science and Technology Commission of Shanghai Municipality,China(19JC1415500,20ZR1465000);Shenzhen Science and Technology Funding(JCYJ20210324120009026);S&T Innovation 2025 Major Special Program of Ningbo(2018B10040)are acknowledged.
It is important to eliminate lipopolysaccharide(LPS)along with killing bacteria in periprosthetic joint infection(PJI)therapy for promoting bone repair due to its effect to regulate macrophages response.Although natur...
关键词：Osteoimmunomodulation ANTIBACTERIAL CHITOSAN PUERARIN LIPOPOLYSACCHARIDE 
An injectable hydrogel combining medicine and matrix with anti-inflammatory and pro-angiogenic properties for potential treatment of myocardial infarction被引量：2
《Regenerative Biomaterials》2023年第1期889-903,共15页Jiayin Feng Min Xing Wenhao Qian Jiajun Qiu Xuanyong Liu 
supported by the National Natural Science Foundation of China(32000945);Young Elite Scientists Sponsorship Program by CAST(YESS)2022-2024QNRC001;Science and Technology Commission of Shanghai Municipality(22ZR1457600,20ZR1452200).
One of the main illnesses that put people’s health in jeopardy is myocardial infarction(MI).After MI,damaged or dead cells set off an initial inflammatory response that thins the ventricle wall and degrades the extra...
关键词：mesoporous silica PUERARIN HYDROGELS ANGIOGENESIS myocardial repair 
Puerarin alleviates sleep disorders in aged mice related to repairing intestinal mucosal barrier
《Natural Products and Bioprospecting》2023年第1期464-476,共13页Qing Tao Jinhua Zhang Qiao liang Shiyu Song Shuxia Wang Xiaoming Yao Qian Gao Lei Wang 
the National Key Research and Development Program of China(No:2020YFC2005300,No:2021YFC2009101);Open/Independent Project of the Center for Translational Medicine and Jiangsu Key Laboratory of Molecular Medicine,Medical School of Nanjing University,and Jiangsu Province Postgraduate Scientific Research Innovation Project(KYCX22-0183).
More and more evidence suggests that puerarin,a potential remedy for gut inflammation,may have an ameliorative effect on sleep disturbances.However,the relationship between puerarin and sleep disruption has not been e...
关键词：Intestinal inflammation Intestinal mucosal barrier Light-induced sleep disorder PUERARIN 
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