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B-CELL: 作品数：162被引量：462H指数：11; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：刘勇刘福生刘元波李扬张俊廷更多>>; 相关机构：郑州大学第一附属医院江西省人民医院第二军医大学北京大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划广东省自然科学基金更多>>

Treatment of immunoglobulin A nephropathy:Current perspective and future prospects: 《World Journal of Clinical Cases》2025年第19期5-10,共6页Yusuf ZiyaŞener SeherŞener; Immunoglobulin(Ig)A nephropathy is the most common type of primary glomerulonephritis globally.It typically manifests with microscopic hematuria and a spectrum of proteinuria,although rapidly progressive glomeruloneph...; 关键词：Immunoglobulin A nephropathy Telitacicept Complement inhibitors B-cell lineage depletion Anti-proteinuric treatment

CD30 influences germinal center B-cell dynamics and the expansion of IgG1-switched B cells: 《Cellular & Molecular Immunology》2024年第12期1410-1425,共16页Yan Wang Ursula Rambold Petra Fiedler Tea Babushku Claas L.Tapken Kai P.Hoefig Thomas P.Hofer Heiko Adler AliÖnder Yildirim Lothar J.Strobl Ursula Zimber-Strobl; supported by the Deutsche Krebshilfe,Nr.70113859 to U.Z.-S.and H.A.,the Wilhelm-Sander-Stiftung Nr.2022.128.1 to A.Ö.Y and U.Z.-S.and the National Institute of Allergy and Infectious Diseases of the National Institutes of Health under award number R01AI170965。; Initially,identified as a Hodgkin lymphoma marker,CD30 was subsequently detected on a subset of human B cells within and around germinal centers(GCs).While CD30 expression is typically restricted to a few B cells,expa...; 关键词：B lymphocytes Germinal center reaction CD30 Conditional mice CD30L Senescence associated T cells(SAT cells)

Retraction:Gamma Irradiation Upregulates B-cell Translocation Gene 2 to Attenuate Cell Proliferation of Lung Cancer Cells Through the JNK and NF-κB Pathways: 《Oncology Research》2024年第9期1527-1527,共1页Oncology Research Editorial Office; Following the publication,concerns have been raised about a number of figures in this article.The western blots in this article were presented with atypical,unusually shaped and possibly anomalous protein bands in man...; 关键词：LUNG raised shaped

B-cell-specific signatures reveal novel immunophenotyping and therapeutic targets for hepatocellular carcinoma: 《World Journal of Gastroenterology》2024年第34期3894-3925,共32页Ke-Quan Xu Zheng Gong Jia-Ling Yang Chu-Qi Xia Jian-Yi Zhao Xi Chen; Supported by the Fundamental Research Funds for the Central Universities(2042024YXB009 to X.C.);Special Foundation for knowledge innovation of Wuhan Science and Technology Innovation Bureau(2023020201020510 to X.C.).; BACKGROUND Immunotherapy presents both promises and challenges in treating hepatocellular carcinoma(HCC)due to its complex immunological microenvironment.The role of B cells,a key part of the immune system,remains unc...; 关键词：B cell Hepatocellular carcinoma Immune microenvironment IMMUNOTHERAPY Molecular subtype

Preclinical evaluation of cyclophosphamide and fludarabine combined with CD19 CAR-T in the treatment of B-cell hematologic malignancies in vivo: 《Oncology Research》2024年第6期1109-1118,共10页ZHIGANG XIA MENGYAO TIAN YUCAI CHENG WENFANG YI ZEFAN DU TIANWEN LI YUCHEN WEN LINDI LI YONG LIU CHUN CHEN; National Natural Science Foundation of China(No.82370164);Sanming Project of Medicine in Shenzhen(No.SZSM202011004);Shenzhen Science and Technology Innovation Commission(JCYJ20180307150419435 and JCYJ20210324123004011).; Background:Chimeric antigen receptor T(CAR-T)cell therapy has achieved marked therapeutic success in ameliorating hematological malignancies.However,there is an extant void in the clinical guidelines concerning the mo...; 关键词：CD19 CAR-T B-cell hematologic malignancies Metabolism In vivo

Bortezomib depended on PRDM1 and TP53 to exert therapeutic effect in activated B-cell-like diffuse large B-cell lymphoma: 《Genes & Diseases》2024年第2期550-553,共4页Jing Tang Yue Li Jiazhu Wu Haorui Shen Hua Yin Jinhua Liang Li Wang Jianyong Li Yi Xia Wei Xu; supported by the National Natural Science Foundation of China(No.81720108002,81700193,82170186);Jiangsu Province's Medical Elite Programme(China)(No.ZDRCA2016022);Project of National Key Clinical Specialty(China),Jiangsu Provincial Special Program of Medical Science(China)(No.BE2017751);National Science and Technology Major F Project(China)(No.2018ZX09734007);Nature Science Foundation for Youths of Jiangsu Province,China(No.BK20220719);China Postdoctoral Science Foundation(No.2021M691336);Jiangsu Post doctoral Science Foundation(China)(No.2021K083A).; PR/SET domain 1(PRDM1)gene is located on chromosome 6q21,encoding the B lymphocyte-induced maturation protein 1(BLIMP1).1 It is reported that loss of PRDM1 function is exacerbated in activated B-cell-like(ABC)-diffuse...; 关键词：PRDM1 TP53 THERAPEUTIC

Alternative Phenotypic Profile for B-Cell Abnormality in a Case at Zinder National Hospital: 《Open Journal of Blood Diseases》2024年第1期8-16,共9页Brah Moustapha Maman Amadou Djibrilla-Almoustapha Moustapha Elhadji-Chefou Abdoul-Aziz Garba Badé Malam-Abdou; Introduction: Since it is impossible to establish a diagnosis in the presence of hyperlymphocytosis not secondary to lymphocytic hyperactivation, we considered a B-lymphoid hematopathy with a non-specific phenotypic p...; 关键词：Hyperlymphocytosis CLL IMMUNOPHENOTYPING MINICHOP

Pathologically expanded peripheral CD4^(+)PD-1^(+)Foxp3^(−) T-cell subset promotes B-cell hyperactivity in patients with rheumatoid arthritis被引量：1: 《Rheumatology & Autoimmunity》2024年第1期27-36,共10页Ziran Bai Rui Liu Jiaqing Liu Cheng Zhang Zilong Wang Jingjing Qi Yawei Tang Xia Li; National Natural Science Foundation of China,Grant/Award Numbers:82071834,82271839,82302047;Doctoral Start-up Foundation of Liaoning Province,Grant/Award Numbers:2023−BS-160;Dalian Medical University Interdisciplinary Research Cooperation Project Team Funding,Grant/Award Numbers:JCHZ2023010.; Background:Rheumatoid arthritis (RA) is an autoimmune disease characterized by destructive polyarthritis, and abnormal T-B-cell interactions may contribute to its pathogenesis. This study aimed to investigate the char...; 关键词：B-cell hyperactivity CD4^(+)PD-1^(+)Foxp3^(−)T cells rheumatoid arthritis type 2 helper T cells

Deep insight into the B-cell associated tertiary lymphoid structure and tumor immunotherapy被引量：1: 《Cancer Biology & Medicine》2024年第2期125-131,共7页Jilong Yang Jin Xu Haotian Liu Wanyi Xiao Gengpu Zhang; Bod et al.1 recently published a study in Nature that garnered attention to B cell-associated anti-tumor immunity and immunotherapy of melanoma and other tumors1.As a promising supplemental immunotherapy to mainstream...; 关键词：IMMUNOTHERAPY IMMUNITY

B-cell and antibody responses to SARS-CoV-2:infection,vaccination,and hybrid immunity被引量：1: 《Cellular & Molecular Immunology》2024年第2期144-158,共15页Dennis Lapuente Thomas H.Winkler Matthias Tenbusch; Deutsche Forschungsgemeinschaft(German Research Foundation)-Projektnummer 215346292[Winkler];Bavarian consortium for research on the pandemic disease COVID-19(FOR-COVID)[Tenbusch].; The emergence of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)in 2019 prompted scientific,medical,and biotech communities to investigate infection-and vaccine-induced immune responses in the context of t...; 关键词：SARS-CoV-2 neutralizing antibodies memory responses vaccines IGG4

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