supported by the Natural Science Foundation of Tianjin Science and Technology Committee(19YFZCSY00020);the National Natural Science Foundation of China(82372818 to XDZ,82103066 to GY;82302887 to HFY,82303210 to YFW);the China Postdoctoral Science Foundation(2022M712389 to HFY;2023M742621 to LNZ,2023M732624 to YFW);Tianjin Key Medical Discipline(Specialty)Construction Project(TJYXZDXK-009A to WL);“14th Five-Year Plan”Tumor Prevention and Treatment Research Project of Tianjin Medical University Cancer Institute and Hospital(No.YZ-03).
Lymphocyte activation gene 3(LAG3),an immune checkpoint molecule expressed on activated T cells,functions as a negative regulator of immune responses.Persistent antigen exposure in the tumor microenvironment results i...
supported by the National Natural Science Foundation of China(No.81720108002,81700193,82170186);Jiangsu Province's Medical Elite Programme(China)(No.ZDRCA2016022);Project of National Key Clinical Specialty(China),Jiangsu Provincial Special Program of Medical Science(China)(No.BE2017751);National Science and Technology Major F Project(China)(No.2018ZX09734007);Nature Science Foundation for Youths of Jiangsu Province,China(No.BK20220719);China Postdoctoral Science Foundation(No.2021M691336);Jiangsu Post doctoral Science Foundation(China)(No.2021K083A).
PR/SET domain 1(PRDM1)gene is located on chromosome 6q21,encoding the B lymphocyte-induced maturation protein 1(BLIMP1).1 It is reported that loss of PRDM1 function is exacerbated in activated B-cell-like(ABC)-diffuse...
We are retracting this article due to certain errors in two figures in the article"TGF-β1-regulated miR-3691-3p targets E2F3 and PRDM1 to inhibit prostate cancer progression"which has been published.An image layout e...
This study was supported by Shanghai Changning District Committee of Science and Technology(CNKW2016Y01);Shanghai Tongren Hospital Project(TRYJ201501);Suzhou Science and Technology Development Program(SYS201717);the Second Affiliated Hospital of Soochow University Advance Research Program of the Natural Science Foundation of China Grants(SDFEYGJ1705);Open project of Jiangsu State Key Laboratory of Radiation Medicine and Projection(GJS1963);the Priority Academic Program Development of Jiangsu Higher Education Institutions.
Transforming growth factor-β1(TGF-β1)acts as a tumor promoter in advanced prostate cancer(PCa).We speculated that microRNAs(miRNAs)that are inhibited by TGF-β1 might exert anti-tumor effects.To assess this,we ident...