云南高校图书馆联盟文献共享服务平台- THYMOPENTIN

THYMOPENTIN: 作品数：14被引量：26H指数：3; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：梅兴国艾国更多>>; 相关机构：军事医学科学院徐州医科大学更多>>; 相关期刊：《Acta Pharmacologica Sinica》《Chemical Research in Chinese Universities》《Journal of Hainan Medical University》《Journal of Chinese Pharmaceutical Sciences》更多>>; 相关基金：国家自然科学基金高等学校学科创新引智计划国家重点基础研究发展计划国家高技术研究发展计划更多>>

Effects of polyol excipient stability during storage and use on the quality of biopharmaceutical formulations被引量：1: 《Journal of Pharmaceutical Analysis》2022年第5期774-782,共9页Min-Fei Sun Jia-Ning Liao Zhen-Yi Jing Han Gao Bin-Bin Shen You-Fu Xu Wei-Jie Fang; generously provided by the National Natural Science Foundation of China(Grant No.:81741144);Ministry of Science and Technology of China(Grant No.:2018ZX09J18107-002).; Biopharmaceuticals are formulated using a variety of excipients to maintain their storage stability.However,some excipients are prone to degradation during repeated use and/or improper storage,and the impurities gener...; 关键词：Excipient stability GC-MS GLYCEROL LC-MS/MS MANNITOL THYMOPENTIN

Thymopentin-loaded phospholipid-based phase separation gel with long-lasting immunomodulatory effects: in vitro and in vivo studies被引量：1: 《Acta Pharmacologica Sinica》2019年第4期514-521,共8页Ting Zhang Xian-yan Qin Xi Cao Wen-hao Li Tao Gong Zhi-rong Zhang; National Natural Science Foundation of China (81690261 and 81673359).; Thymope ntin (TP5) is an effective immuno modulatory age nt for autoimm une disease that has bee n used clin ically for decades. However, its application is greatly limited by its extremely short half-life in vivo, po...; 关键词：THYMOPENTIN phospholipid-based PHASE separation gel (PPSG) PHASE transition SUSTAINED drug release pharmacokinetics immunoregulatory effect

Effects of lentinan and thymopentin combined with adjuvant chemotherapy on immunity, oxidative stress, matrix metalloproteinases and related factors in patients with tongue squamous cell carcinoma: 《Journal of Hainan Medical University》2018年第23期54-58,共5页Bo Zhao Yi Li Yan-Lin Xiong; Objective:To investigate the effects of lentinan and thymopentin combined with adjuvant chemotherapy on immunity, oxidative stress, matrix metalloproteinases and related factors in patients with tongue squamous cell c...; 关键词：LENTINAN THYMOPENTIN Chemotherapy Tongue squamous cell carcinoma IMMUNITY Oxidative stress Matrix METALLOPROTEINASE Correlation factor

Effects of ulinastatin combined with thymopentin on cellular immunity, humoral immunity and stress response in severe pneumonia: 《Journal of Hainan Medical University》2018年第20期13-16,共4页Yan Zhong Bing-Yang Chen Wen-Hui Huang Xue Xiong; Objective:To explore the effects of ulinastatin combined with thymopentin on cellular immunity, humoral immunity and stress response in severe pneumonia.Methods: A total of 102 cases of severe pneumonia treated in our...; 关键词：ULINASTATIN THYMOPENTIN SEVERE PNEUMONIA Cellular IMMUNITY HUMORAL IMMUNITY Stress response

Implantable sandwich PHBHHx film for burst-free controlled delivery of thymopentin peptide被引量：2: 《Acta Pharmaceutica Sinica B》2018年第3期432-439,共8页Ke Peng Chengyu Wu Guoxu Wei Jinghui Jiang Zhirong Zhang Xun Sun; supported by the National Natural Science Foundation of China(No.81673362); Sustained release and non-parental formulations of peptides and protein drugs are highly desirable because of enhanced therapeutic effects as well as improved patient compliance. This is especially true for small pept...; 关键词：THYMOPENTIN Sustained release Burst-free release Immune enhancement PHBHHX

Synergistic immunoreaction of acupuncture-like dissolving microneedles containing thymopentin at acupoints in immune-suppressed rats被引量：11: 《Acta Pharmaceutica Sinica B》2018年第3期449-457,共9页Qian Zhang Chuncao Xu Shiqi Lin Huanbin Zhou Gangtao Yao Hu Liu Lili Wang Xin Pan Guilan Quan Chuanbin Wu; supported by the Science and Technology Plan Projects of Guangdong Province(Grant No.2015B020232010);Public Research Platform for Production Technology of Novel Pharmaceutical Formulations,Science and Technology Foundation Guangzhou(201509030006);National Natural Science Foundation of China(81473155);111 project(B16047);the Key Laboratory Foundation of Guangdong Province(2011A060901014); Dissolving microneedles carried drug molecules can effectively penetrate the stratum corneum of skin to improve the transdermal drug delivery. The traditional Chinese medicine acupuncture is based on the needle stimul...; 关键词：Dissolving microneedles Acupoint Thymopentin(TP5) Immune-modulating effects transdermal drug delivery ACUPUNCTURE

Effect of Xuebijing, thymopentin combined with symptomatic treatment on inflammatory response process in elderly patients with severe pneumonia: 《Journal of Hainan Medical University》2017年第17期25-28,共4页Yan-Gang Zhu Xin-Hui Jia Zhen-Jie Shi Hai-Bo Jiang Ming-Hua Du; Objective:To study the effect of Xuebijing, thymopentin combined with symptomatic treatment on inflammatory response process in elderly patients with severe pneumonia. Methods: A total of 60 elderly patients with seve...; 关键词：ELDERLY SEVERE PNEUMONIA XUEBIJING THYMOPENTIN INFLAMMATORY response

The effect on immune function and inflammatory factors of adjuvant antibiotic therapy through Xuebijing combined with thymopentin in elderly patients with severe pneumonian: 《Journal of Hainan Medical University》2017年第11期26-29,共4页Yi-Ya Jiang Tie-Feng Qiu Zhi-Fang Zhuang; Objective:To investigate the effect on immune function and inflammatory factors of adjuvant antibiotic therapy through Xuebijing combined with thymopentin in elderly patients with severe pneumonia.Methods:Divided 100 ...; 关键词：Elderly patient with severe PNEUMONIA XUEBIJING THYMOPENTIN Immune function INFLAMMATORY factors

Immune formulation-assisted conventional therapy on anti-infective effectness of multidrug-resistant Mycobacterium tuberculosis infection mice被引量：7: 《Asian Pacific Journal of Tropical Medicine》2016年第3期288-292,共5页Xiu-Li Yuan Qiang Wen Ming-De Ni Li-Kun Wang; Science and Technology Development Program of Linyi City(No:201113018); Objective:To study the effect of immune formulation-assisted conventional therapy on antiinfective ability of multidrug-resistant Mycobacterium tuberculous infection mice.Methods:BALB/c mice were used as experimental ...; 关键词：MYCOBACTERIUM TUBERCULOSIS MULTIDRUG resistance THYMOPENTIN IMMUNE function

Influence of thymopentin-5 on renal pathology and relevant indexes of serum in rats with acute kidney injury caused by sepsis: 《Discussion of Clinical Cases》2015年第3期17-21,共5页Yongmeng Zhu Lingfeng Wang Weidong Guo; Objective:To discuss thymopentin-5 on renal pathology and relevant indexes of serum with sepsis-caused acute kidney injury(AKI)caused by cecal ligation and puncture(CLP).Methods:90 cases of healthy and male SD rats we...; 关键词：Thymopentin-5 SEPSIS Acute kidney injury

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