LENTINAN

作品数：18被引量：39H指数：3
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相关作者：钱建亚卜敏刘栋刘建文徐晓飞更多>>
相关机构：扬州大学无限极(中国)有限公司上海中医药大学华南理工大学更多>>
相关期刊：《食品工业科技》《World Journal of Clinical Oncology》《Journal of Hainan Medical University》《中国中西医结合杂志》更多>>
相关基金：广东省自然科学基金中央高校基本科研业务费专项资金更多>>
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Shiitake-derived lentinan preventsα-synuclein aggregation,disassembles amyloid aggregates,and protects dopaminergic neurons被引量：1
《Science China Materials》2024年第12期3898-3907,共10页Fanling Meng Yanan Li Siyu Wang Yanni Pan Shangbang Gao Liang Luo 
supported by the National Natural Science Foundation of China(22077038,22477032,32371189);National Undergraduate Innovation and Entrepreneurship Research Practice Program(201910487066);Huazhong University of Science and Technology Supportive Fund for Basic Research。
Parkinson’s disease(PD)is the second largest degenerative disease of central nervous system around the world.α-Synuclein(α-syn)is the main component of Lewy body amyloid deposits in the brain of PD patients and ass...
关键词：Α-SYNUCLEIN protein aggregation inhibition LENTINAN DISASSEMBLY 
Selenium nanoparticles enhance the chemotherapeutic efficacy of pemetrexed against non-small cell lung cancer
《Chinese Chemical Letters》2024年第12期228-233,共6页Zhi Li Shuya Pan Yuan Tian Shaowei Liu Weifeng Wei Jinlin Wang Tianfeng Chen Ling Wang 
supported by National Natural Science Foundation for Distinguished Young Scholars(No.82225025);National Natural Science Foundation of China(Nos.21877049,32171296)。
Selenium(Se)plays an important role in the development and treatment of lung cancer,yet its specific mechanisms remain elusive.Lower Se level in serum was noted in lung cancer patients compared to normal controls.Ther...
关键词：Selenium nanoparticles LENTINAN CHEMOTHERAPY PEMETREXED Non-small cell lung cancer Apoptosis 
Advances in Research of Biological Activity,Action Mechanism and Structure-Activity Relationship of Lentinan
《Asian Agricultural Research》2023年第12期28-38,共11页Jiawen LI Chao ZHAO Xiaojian GONG Huaguo CHEN Xin ZHOU 
Supported by National Natural Science Foundation of China (82360716).
Lentinula edodes is the second largest edible mushroom in the world and is widely used as food and medicine.Modern research shows that lentinan(LNT)is the main active component of L.edodes.It has anti-cancer,treatment...
关键词：LENTINAN BIOLOGICAL ACTIVITIES Action mechanism STRUCTURE-ACTIVITY RELATIONSHIP 
Inhibition of H_(2)O_(2)-induced TM3 cell apoptosis by oxidative stress by lentinan functionalized selenium nanoparticles through JAK2/STAT-3 and P53 pathways被引量：1
《BIOCELL》2023年第6期1397-1405,共9页MIAOMIAO LI ZILIN ZHENG JUNYI KE JIEYI LUO FAN JIANG YANXIA QU BING ZHU YINGHUA LI LIANDONG ZUO 
Science and Technology Projects in Guangzhou(202201020632,202201020638,202206010100,202201020655,and 202102010202);the Guangdong Natural Science Foundation(2020A1515110648);the Open Project of Guangdong Key Laboratory of Marine Materia(LMM2020-7);the Open Fund of Guangdong Provincial Key Laboratory of Functional Supramolecular Coordination Materials and Applications(2020A03);the Guangzhou Medical University Students’Science and Technology Innovation Project(2021AEK119 and 02-408-2203-2079).
Background:Nano-selenium has been widely used in antiviral and anticancer therapy,and has the advantages of good targeting and low toxicity.For the first time,we combined male reproduction with nano-selenium to invest...
关键词：Selenium nanoparticles LENTINAN ROS Antioxidant 
Inhibition of H_(2)O_(2)-induced apoptosis of GC2-spg cells by functionalized selenium nanoparticles with lentinan through ROSmediated ERK/p53 signaling pathways被引量：1
《BIOCELL》2023年第2期401-408,共8页MIAOMIAO LI DANYANG CHEN JUNYI KE RUILIN ZHENG JINGYAO SU ZILIN ZHENG JIEYI LUO HANRAN MAI FAN JIANG YANXIA QU XIAOQIONG GU BING ZHU YINGHUA LI LIANDONG ZUO 
funded by the open Project of Guangdong Key Laboratory of Marine Materia(LMM2020-7);the science and technology projects in Guangzhou(202201020632,202201020638,202206010100,202201020655 and 202102010202);the Guangdong Natural Science Foundation(2020A1515110648);the Open Fund of Guangdong Provincial Key Laboratory of Functional Supramolecular Coordination Materials and Applications(2020A03);The Guangzhou Medical University Students’Science and Technology Innovation Project(02-408-2203-2079,2021AEK119).
AH_(2)O_(2)-induced oxidative stress injury cell model was established to investigate the antioxidant effect of nanoselenium on mouse spermatocyte lines and the regulation mechanism of the expression level and activit...
关键词：Selenium nanoparticles LENTINAN ROS ANTIOXIDANT 
Correlation of conformational changes and immunomodulatory activity of lentinan under different subcritical water temperature被引量：1
《Food Bioscience》2022年第6期646-658,共13页Can Zhang Qian Fu Yu Hua Haihui Zhang Yuqing Duan 
funded by the National Natural Science Foundation of China(32072354);Key R&D Program of Ningxia Hui Autonomous Region(No.2022BBF03016);Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD).
In order to reveal the intrinsic nature of the reduction or disappearance of biological activity in the processing and preparation of polysaccharides,and realize the effective control of highly active polysaccharides,...
关键词：Subcritical water LENTINAN TEMPERATURE Chain conformation Immunomodulatory activity 
Bioactive polysaccharides from medicinal mushrooms:A review on their isolation,structural characteristics and antitumor activity
《Food Bioscience》2022年第5期119-129,共11页Juliana Garcia Francisca Rodrigues Maria Jose Saavedra Fernando M.Nunes Guilhermina Marques 
funded by the project I&T Companies in Co-Promotion FungiTech,Norte-01-0247-FEDER-033788;R&D project Fungi4Health-Valorization of agro-industrial co-products by mushroom production and development of functional food and natural cosmetics(NORTE-01-0247-FEDER-070171);National Funds by FCT-Portuguese Foundation for Science and Technology,under the project UIDB/04033/2020(CITAB-Center for the Research and Technology of Agro-Environmental and Biological Sciences).
Mushrooms either alone or in combination with conventional cancer treatment have been enhanced the efficacy of chemotherapy and radiotherapy improving the patients’quality of life.These therapy effects have been attr...
关键词：LENTINAN D-fraction SCHIZOPHYLLAN Anticancer activity 
Lentinan administration alleviates diarrhea of rotavirus-infected weaned pigs via regulating intestinal immunity被引量：12
《Journal of Animal Science and Biotechnology》2021年第3期1125-1137,共13页Xiangqi Fan Haiyan Hu Daiwen Chen Bing Yu Jun He Jie Yu Junqiu Luo Erik Eckhardt Yuheng Luo Jianping Wang Hui Yan Xiangbing Mao 
This study was financially supported by the grant from the earmarked fund for the China Agriculture Research System(CARS-35);the fund from the Project of SAU-Adisseo Centre of Research on Nutrition and Health;the fund from Agricultural Science and Technology Achievement Transformation Fund Project of Sichuan Province(2016NYZ0052 and 20NZZH0057).
Background:Lentinan(LNT)may regulate many important physiological functions of human and animals.This study aimed to verify whether LNT administration could relieve diarrhea via improving gut immunity in rotavirus(RV)...
关键词：Gut immunity IPEC-J2 cells LENTINAN ROTAVIRUS Weaned pigs 
Rapid Quantification of Bioactive Lentinan with an Aniline Blue Fluorescent Method被引量：1
《Pharmacology & Pharmacy》2019年第6期318-328,共11页Luodi Fan Tong Li Minghua Hu Fangli Ma Boyang Yu Jiangwei Tian 
Lentinan is a clinically approved immune modulator and its anticancer and immunomodulatory bioactivity is found to be dependent on its triple helical conformation. Therefore, the development of rapid and convenient me...
关键词：LENTINAN Triple HELICAL CONFORMATION ANILINE BLUE Fluorescence Detection Health TONIC Solution 
Effects of lentinan and thymopentin combined with adjuvant chemotherapy on immunity, oxidative stress, matrix metalloproteinases and related factors in patients with tongue squamous cell carcinoma
《Journal of Hainan Medical University》2018年第23期54-58,共5页Bo Zhao Yi Li Yan-Lin Xiong 
Objective:To investigate the effects of lentinan and thymopentin combined with adjuvant chemotherapy on immunity, oxidative stress, matrix metalloproteinases and related factors in patients with tongue squamous cell c...
关键词：LENTINAN THYMOPENTIN Chemotherapy Tongue squamous cell carcinoma IMMUNITY Oxidative stress Matrix METALLOPROTEINASE Correlation factor 
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