TONIC

作品数：72被引量：127H指数：6
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Validation of Anti-Hair Loss Tonic Containing 1.0%Arctium Lappa Root Extract for Chinese Consumers
《China Detergent & Cosmetics》2025年第1期52-57,共6页Zeng Haifeng Lin Xianting Yang Jianzhong Iwano Hideki Sawaki Shigetoyo 
A hair tonic containing 1.0%Arctium lappa root extract(ALRE)was evaluated for its efficacy and tolerability in Chinese consumers.ALRE was selected based on its ability to promote Collagen Type XVII Alpha 1(COL17A1)syn...
关键词：Arctium lappa root extract hair loss hair outer root sheath cells Collagen Type XVII Alpha 1(COL17A1) clinical efficacy Chinese consumers 
Electroclinical characteristics and therapies of tonic spasms
《Acta Epileptologica》2024年第3期189-203,共15页Xi Peng Yangmei Chen Zezhi Wang Xinbo Zhang Bi Wang Lang Jin Xiaoli Wang Na Yuan Xiaojing Hu Xiaomu Wang Yonghong Liu 
National Natural Science Foundation of China(81401073 to XP);National Key R&D Program of China(2022YFC2503806)and NSFC(8237203)to YL;Province Natural Science Foundation of Shaanxi Province(2021SF-094 to XW).
Backgroud Epileptic spasms followed by a tonic component have been frequently observed in patients with late-onset spasms(LOS).However,there is a lack of comprehensive analysis and summary of clinical data related to ...
关键词：Epilepsy Tonic spasm ELECTROENCEPHALOGRAPHY 
CAR-Toner:an Al-driven approach for CAR tonic signaling prediction and optimization被引量：2
《Cell Research》2024年第5期386-388,共3页Shizhen Qiu Jian Chen Tao Wu Li Li Gang Wang Haitao Wu Xianmin Song Xuesong Liu Haopeng Wang 
the National Natural Science Fund Original Exploratory Program(82350110);the National Key R&D Program of China(2019YFA0111000);Program of Shanghai Academic/Technology Research Leader,Shanghai Frontiers Science Center for Biomacromolecules and Precision Medicine at ShanghaiTech University,the Central Guidance on Local Science and Technology Development Fund(YDZX20233100001002);Shanghai Local College Capacity Building Project(22010502700);J.C.was granted by Youth Foundation of the National Natural Science Foundation of China(82102863),Original Exploration Project of Shanghai Natural Science Foundation(21ZR1480200);Shanghai Rising-Star Program(23QA1400900);Shanghai Youth Medical Talents-Specialist Program(SHWSRS(2023)_062);"Zhuo-Xue Plan"of Fudan University.
Dear Editor,Tonic signaling of chimeric antigen receptors(CARs)plays a pivotal role in governing CAR-T cell fitness:inefficient tonic signaling results in poor CAR-T persistence,while excessive tonic signaling leads t...
关键词：SERVER optimization PREDICTION 
A finTRIM member 100 (FTR100) is unique to Otomorpha fish for constitutive regulation of IFN response
《Water Biology and Security》2023年第2期80-90,共11页Wen-Hao Guo Cheng Dan Xiu-Ying Gong Yi-Lin Li Hao-Yu Sun Zi-Ling Qu Li-Li An Xiang Zhao Jie Mei Jian-Fang Gui Yi-Bing Zhang 
supported by grants from the National Key R&D Program of China(2022YFF1000302);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA24010308);the National Natural Science Foundation(31972826 and 32102838);the Freshwater Ecology and Biotechnology Laboratory(2019FBZ04).
Vertebrate interferon(IFN)expression is fine-tuned in order to avoid excessive tissue injury under normal conditions and during virus infection.FinTRIM(fish novel TRIM,FTR)proteins are reported to regulate the fish IF...
关键词：Constitutive expression FTR100 Homeostatic regulation Lineage-specific expansion Tonic IFN response 
Tuning charge density of chimeric antigen receptor optimizes tonic signaling and CAR-T cell fitness被引量：12
《Cell Research》2023年第5期341-354,共14页Jian Chen Shizhen Qiu Wentao Li Kun Wang Yu Zhang Han Yang Baichuan Liu Guangfei Li Li Li Min Chen Junjie Lan Jiahua Niu Peijie He Lei Cheng Gaofeng Fan Xin Liu Xianmin Song Chenqi Xu Haitao Wu Haopeng Wang 
the Animal Facility at the National Facility for Protein Science in Shanghai,Zhangjiang Lab for providing the support in mouse housing and care,and Molecular and Cell Biology Core Facility(MCBCF)and Molecular Imaging Core Facility(MICF)at the School of Life Science and Technology,ShanghaiTech University for providing technical support.This work was supported by grants from the National Key R&D Program of China(2019YFA0111000 to H.Wang);the Double First-Class Initiative Fund of ShanghaiTech University,Shanghai Frontiers Science Center for Biomacromolecules and Precision Medicine at ShanghaiTech University,and Shanghai Local College Capacity Building Project(22010502700);J.C.was granted by Youth Foundation of the National Natural Science Foundation of China(82102863);Original Exploration Project of Shanghai Natural Science Foundation(21ZR1480200);H.Wu was granted by the National Natural Science Foundation of China(82271149)and Shanghai Technology Innovation Project(21Y11912000);C.X.was granted by CAS Young Scientists in Basic Research Program(YSBR-014);CAS Shanghai Branch Special Plan for Basic Research(JCYJ-SHFY-2022-009)。
Tonic signaling of chimeric antigen receptor(CAR),i.e.,the spontaneous CAR activation in the absence of tumor antigen stimulation,is considered to be a pivotal event controlling CAR-T efficacy.However,the molecular me...
关键词：STIMULATION maintained MAINTAIN 
Positively charged patches:tonic for CAR ftness
《Cell Research》2023年第5期331-332,共2页Meraj H.Khan Jan Joseph Melenhorst 
Tonic signaling is a constitutive low-level activation of chimeric antigen receptors(CARs)in the absence of tumor antigen and plays an imperative role in the CAR-T efficacy.In a recent paper published in Cell Research...
关键词：CAR efficacy. 
Clinical Effect of Left-supplemented Myelogenous Blood Soup on Leukopenia after Chemotherapy for Acute Leukemia
《外文科技期刊数据库(文摘版)医药卫生》2022年第2期169-172,共4页TONGLi HUOJinhui HANTing LIBaifeng 
Objective: to treat leukemia patients with chemotherapy with leukemia reduction symptoms with left supplemented myeloid blood soup and analyze its effect. Methods: a total of 82 patients were selected by double-blind ...
关键词：left tonic myelogenous blood soup acute leukemia LEUKOPENIA therapeutic effect 
Screening for main components associated with the idiosyncratic hepatotoxicity of a tonic herb,Polygonum multiflorum
《Frontiers of Medicine》2021年第2期330-332,共3页Chunyu Li Ming Niu Zhaofang Bai Congen Zhang Yanling Zhao Ruiyu Li Can Tu Huifang Li Jing Jing Yakun Meng Zhijie Ma Wuwen Feng Jinfa Tang Yun Zhu Jinjie Li Xiaoya Shang Zhengsheng Zou Xiaohe Xiao Jiabo Wang 
Erratum to Frontiers of Medicine 201711(2):253–265 https://doi.org/10.1007/s11684-017-0508-9 The original version of this article unfortunately contained some mistakes.The panel of“LPS–/drug–”in Fig.3B(Page 259),...
关键词：Medicine hepato corrected 
Innovative Light Therapy: 4. Influence of Polarization and Wavelength Range of Light on the Effectiveness of Its Pain Relief Action被引量：2
《Journal of US-China Medical Science》2021年第1期1-19,共19页Sergiy A.Gulyar Zynaida A.Tamarova 
We studied the dynamics of the tonic pain response(formalin test)and changes in the pain threshold to electrical stimulation(vocalization test on an electric platform)in animals depending on the polarization and wavel...
关键词：PHOTOBIOMODULATION Bioptron polarized polychromatic light red light colour therapy ANALGESIA acute pain tonic pain AP points pain and non-pain behavioural reactions. 
TCM diagnosis and treatment theory of chronic complete occlusion of coronary artery based on etiology and pathogenesis
《Journal of Hainan Medical University》2020年第21期60-64,共5页Wen-Bin Zhang Kai-Ming Chen Zhen Wang Yi-Tao Xue 
National natural science foundation of China(No.81774247)
Chronic total occlusive disease of the coronary artery belongs to the category of"chest palsy"and"true heart pain"in traditional Chinese medicine.Its etiology has two aspects:deficiency of blood,blood stasis,qi stagna...
关键词：CTO disease TCM etiology and pathogenesis Combination of tonic and tonic Xuanbi Tongyang Huoxuetongluo Aromatic Wentong 
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