XUEBIJING

作品数：27被引量：94H指数：6
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相关领域：医药卫生农业科学更多>>
相关作者：陆璐王红义罗晓红万东君史智勇更多>>
相关机构：兰州军区兰州总医院大连医科大学附属第一医院浙江大学医学院附属第一医院更多>>
相关期刊：《实验动物与比较医学》《Journal of Traditional Chinese Medicine》《Journal of Clinical and Nursing Research》《Medicinal Plant》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划甘肃省自然科学基金更多>>
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Xuebijing enhances antitumor efficacy of anti-CD19 CAR-T cells
《Journal of Traditional Chinese Medical Sciences》2024年第4期466-475,共10页Jingjing Zhu Jing Zhang Ping Wang Xiuying Liu Jingjing Liu Yichao Feng Mary Yue Jiang Zhiqiao Feng Xiaoqing Yao Jianxun Wang 
supported by the Beijing Double Class One Human Resource Office-High-Level-Jianxun Wang's Research Team Funding Project of China(1000041510155);the Research Startup Fund Program at the Beijing University of Chinese Medicine(90011451310032).
Objective:To investigate the effects and mechanisms of Xuebijing injection(XBJ)on Chimeric antigen receptor-T(CAR-T)cell function and its therapeutic potential against CAR-T therapy-associated cytokine storms(CRS).Met...
关键词：XUEBIJING Chimeric antigen receptor-T Inflammatory cytokines MACROPHAGE Cytokine release syndrome 
Analysis of the Efficacy of Xuebijing Combined with Antimicrobials in the Treatment of Intensive Care Unit Patients with Severe Pneumonia
《Journal of Clinical and Nursing Research》2024年第6期123-128,共6页Han Zou Yuting Song Jiaju Ma Hebu Qian Yueping Yao 
Objective:To analyze the therapeutic effect of Xuebijing+antimicrobials in intensive care unit(ICU)patients with severe pneumonia.Methods:60 ICU patients with severe pneumonia from June 2021 to June 2023 were selected...
关键词：Intensive care unit severe pneumonia Antimicrobials XUEBIJING EFFICACY 
Xuebijing improves intestinal microcirculation dysfunction in septic rats by regulating the VEGF-A/PI3K/Akt signaling pathway
《World Journal of Emergency Medicine》2024年第3期206-213,共8页A-ling Tang Yan Li Li-chao Sun Xiao-yu Liu Nan Gao Sheng-tao Yan Guo-qiang Zhang 
supported by a grant from National Natural Science Foundation of China (82272196)。
BACKGROUND:This study aims to explore whether Xuebijing(XBJ) can improve intestinal microcirculation dysfunction in sepsis and its mechanism.METHODS:A rat model of sepsis was established by cecal ligation and puncture...
关键词：SEPSIS XUEBIJING Vascular endothelial growth factor A MICROCIRCULATION Rat Phosphoinositide 3-kinase Protein kinase B 
Pharmacologically significant constituents collectively responsible for anti-sepsis action of XueBiJing,a Chinese herb-based intravenous formulation被引量：3
《Acta Pharmacologica Sinica》2024年第5期1077-1092,共16页Chen Cheng Chao Ren Mu-zi Li Yi-hui Liu Ren-qi Yao Yang Yu Xuan Yu Jian-li Wang Li-xue Wang Yu-chun Leng Hui Zhang Fei-fei Du Ning Dong Feng-qing Wang Yao Wu Fang Xu Xiao-mei Zhu Gui-ping Zhang Kai Dong Si Liu Xiao-qing Yao Chuan Li Yong-ming Yao 
funded by National Natural Science Foundation of China(82192912,82074176,81801935,and 82272187);Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(ZYYCXTD-C-202009);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA12050306).
Sepsis,a life-threatening health issue,lacks effective medicine targeting the septic response.In China,treatment combining the intravenous herbal medicine XueBiJing with conventional procedures reduces the 28-day mort...
关键词：Traditional Chinese medicine XUEBIJING SEPSIS mortality pharmacokinetic compatibility POLYPHARMACOLOGY 
Molecular mechanism of Xuebijing in treating pyogenic liver abscess complicated with sepsis被引量：3
《World Journal of Emergency Medicine》2024年第1期35-40,共6页Wei Zhou Maiying Fan Xiang Li Fang Yu En Zhou Xiaotong Han 
supported by Hunan Province Key Research and Development Program(2020SKC2004).
BACKGROUND:Xuebijing(XBJ)can alleviate the inflammatory response,improve organ function,and shorten the intensive care unit(ICU)stay in patients with pyogenic liver abscess(PLA)complicated with sepsis,but the molecula...
关键词：Xuebijing injection Pyogenic liver abscess SEPSIS 
Xuebijing alleviates LPS-induced acute lung injury by downregulating pro-inflammatory cytokine production and inhibiting gasdermin-E-mediated pyroptosis of alveolar epithelial cells被引量：6
《Chinese Journal of Natural Medicines》2023年第8期576-588,共13页ZHANG Cuiping CHEN Xiaoyan WEI Tianchang SONG Juan TANG Xinjun BI Jing CHEN Cuicui ZHOU Jian SU Xiao SONG Yuanlin 
supported by the National Natural Science Foundation of China(Nos.82130001,82200089,8173000,81800077,and 82070045);Shanghai Sailing Program(No.22YF1406100);the National Key R&D Plan(No.2020YFC2003700);the Science and Technology Commission of Shanghai Municipality(Nos.20Z11901000,20DZ2261200,and 20XD1401200);Shanghai Municipal Science and Technology Major Project,Clinical Research Plan of SHDC(No.SHDC2020CR5010-002);Shanghai Municipal Key Clinical Specialty(No.shslczdzk02201).
Acute lung injury/acute respiratory distress syndrome(ALI/ARDS)is characterized by diffuse alveolar injury primarily caused by an excessive inflammatory response.Regrettably,the lack of effective pharmacotherapy curre...
关键词：PYROPTOSIS Gasdermin-E TNF-α XUEBIJING Acute lung injury 
Novel assays for quality evaluation of XueBiJing:Quality variability of a Chinese herbal injection for sepsis management被引量：7
《Journal of Pharmaceutical Analysis》2022年第4期664-682,共19页Xuan Yu Wei Niu Ya-Ya Wang Olajide E.Olaleye Jia-Nan Wang Meng-Yuan Duan Jun-Ling Yang Rong-Rong He Zi-Xuan Chu Kai Dong Gui-Ping Zhang Chang-Xiao Liu Chen Cheng Chuan Li 
funded by grants from the National Natural Science Foundation of China(Grant Nos.:82074176 and 81503345);Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(Grant No.:ZYYCXTD-C-202009);the National Key R&D Program of China(Grant No.:2018YFC1704500).
XueBiJing is an intravenous five-herb injection used to treat sepsis in China.The study aimed to develop a liquid chromatography-tandem mass spectrometry(LC-MS/MS)-or liquid chromatography-ultraviolet(LC-UV)-based ass...
关键词：XUEBIJING Chinese herbal medicine Quality variability Quality marker One-point calibration 
Effect of traditional Chinese preparation Xuebijing on inflammatory markers in patients with ventilator-associated pneumonia被引量：2
《Journal of Acute Disease》2021年第5期216-220,共5页Hong-wei Zhang Li-you Wei Ji-xuan Wang Shu-zheng Liu Dan Xing Rui Zhang Hui Guo Li-juan Chen Jing Zhang 
This work was supported by the Talent Funding Project of Tangshan City in Hebei Province(No.a201902005).
Objective:To observe the effect of Xuebijing,a complex traditional Chinese preparation,on inflammation and prognosis of patients with pneumonia.Methods:The patients with ventilator-associated pneumonia in the intensiv...
关键词：Xuebijing injection Ventilator-associated pneumonia C-reactive protein Clinical pulmonary infection score APACHEⅡ 
Uncovering the multi-target pharmacological mechanism of Xuebijing injection against sepsis by a systems pharmacology approach
《TMR Modern Herbal Medicine》2021年第1期63-78,共16页Ping Wang Jingjing Zhu Jie Zhai Xiaorui Li Hongcai Shang Jianxun Wang 
This work was supported by start-up funds from Beijing University of Chinese Medicine to Jianxun Wang(grant number 1000041510051).
Sepsis is a life-threatening organ dysfunction that is associated with a high risk of death.Xuebijing(XBJ)injection,a Chinese herbal compound preparation,has been widely used for the treatment of sepsis in China.The p...
关键词：XUEBIJING SEPSIS MULTI-TARGET Mechanism Systems pharmacology 
The effect of Xuebijing on burn patients and its effect on pain and wound healing
《Journal of Hainan Medical University》2020年第22期10-13,共4页Le Guan Bao-Guo Chen Hui-Feng Song Ning Kang Yan Wu 
National natural science foundation of China(No.81201217,31300801)
Objective:To explore the therapeutic effect of Xuebijing on burn patients and its effect on pain and wound healing.Methods:The burn patients treated in our hospital were selected and divided into two groups according ...
关键词：XUEBIJING BURN PAIN Wound healing 
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