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Correlations of vancomycin trough concentration and its efficacy and toxicity in patients in the intensive care unit
《World Journal of Clinical Cases》2025年第16期18-28,共11页Teng Guo Li-Ying Du Ming-Feng Liu Xia-Jin Zhou Xin-Ran Chen 
Supported by the Key Project Plan of Health and Medical Science Research in Hebei Provincial Health Commission,No.20190745.
BACKGROUND Plasma concentration monitoring is crucial for optimizing vancomycin use,particularly in patients in the intensive care unit(ICU).However,the reference interval for vancomycin plasma concentration remains u...
关键词：VANCOMYCIN Therapeutic drug monitoring Intensive care unit Trough concentration Methicillin-resistant Staphylococcus aureus infection Area under the curve 
Efficacy of catheter-based ultrasound renal denervation in the treatment of hypertension
《World Journal of Clinical Cases》2025年第16期29-37,共9页Yi-Chao Ou Xin-Yuan Peng Jing-Xi Yang Bo-Yu Chen Peng-Fei Chen Mao Liu 
Supported by Sichuan Provincial Medical Research Youth Innovation Project,No.Q22063;Guang'an District People's Hospital Joint Development Research Project,No.2024 LHFZ04。
BACKGROUND Hypertension(HTN)is a prevalent chronic health condition that significantly increases the risk of cardiovascular diseases-associated mortalities.Despite the use of antihypertensive medications,numerous pati...
关键词：HYPERTENSION Renal denervation ULTRASOUND Randomized controlled trial META-ANALYSIS 
B-type natriuretic peptide efficacy compared to fragmented QRS for diastolic dysfunction screening in patients with type 2 diabetes
《World Journal of Diabetes》2025年第4期84-95,共12页Kunimasa Yagi Daisuke Chujo Isao Usui Jian-Hui Liu Atsushi Nohara Asako Enkaku Shirozu Akiko Takikawa Hisae Honoki Shiho Fujisaka Hideki Origasa Hayato Tada 
Supported by the JSPS KAKENHI,No.JP21K10300 and No.JP24K02714.
BACKGROUND Early diagnosis of left ventricular diastolic dysfunction(LVDD)is essential for preventing heart failure.B-type natriuretic peptide(BNP)is a viable marker for predicting LVDD,as elevated BNP levels have bee...
关键词：B-type natriuretic peptide Diastolic dysfunction Fragmented QRS Heart failure with preserved ejection fraction OVERWEIGHT Type 2 diabetes 
Efficacy of modified pancreatic duct stent drainage during endoscopic retrograde cholangiopancreatography for common bile duct stones
《World Journal of Gastrointestinal Surgery》2025年第4期120-131,共12页Li-Jia Qian Chen Xu Jian-Rong Wang Jun Quan 
BACKGROUND Common bile duct stones pose a high risk of recurrence or disease progression if not promptly treated.However,there is still no optimal treatment approach.AIM To investigate the clinical efficacy of modifie...
关键词：Modified pancreatic duct stent drainage Endoscopic retrograde cholangiopancreatography Common bile duct stones Curative effect COMPLICATIONS 
Short-term efficacy of laparoscopic radical resection for colorectal cancer and risk of unplanned reoperation after surgery
《World Journal of Gastrointestinal Surgery》2025年第4期140-149,共10页Wen-Bin Li Jiang Li Wei Yu Jian-Hua Gao 
BACKGROUND Surgery is the first choice of treatment for patients with colorectal cancer.Traditional open surgery imparts great damage to the body of the patient and can easily cause adverse stress reactions.With the c...
关键词：Colorectal cancer Laparoscopic surgery LAPAROTOMY Short-term efficacy Complications 
Evaluation of the Efficacy of Endoscopic Submucosal Dissection for the Treatment of≥40 mm Protruding Colorectal Tumors
《Journal of Clinical and Nursing Research》2025年第4期104-109,共6页Yan Chen Ying Chang 
Clinical Study on Endoscopic Resection of Colorectal Submucosal Tumors Using Underwater Combined with Metal Clip-Assisted Snare,China(Grant No.2441ZF271)。
Objective:To explore the effectiveness and safety of endoscopic submucosal dissection(ESD)in the treatment of≥40 mm protruding colorectal tumors.Methods:Sixty-five patients with colorectal tumors who underwent surgic...
关键词：Endoscopic submucosal dissection Protruding colorectal tumor Resection rate Adverse events 
Efficacy of recombinant human thrombopoietin in patients with acute-on-chronic liver failure and thrombocytopenia:A prospective,open-label study
《World Journal of Gastroenterology》2025年第14期61-70,共10页Gang Liu Fei Tang Tao Wang Jun-Qing Yan Feng-Hui Li Fu-Shuang Ha Xu Zhang Li Jing Jing Liang 
Supported by Tianjin Key Medical Discipline(Specialty)Construction Project,No.TJYXZDXK-034A.
BACKGROUND Patients with acute-on-chronic liver failure(ACLF)have a high mortality rate,poor prognosis,and often experience concurrent thrombocytopenia and bleeding events.AIM To evaluate the efficacy and safety of re...
关键词：Recombinant human thrombopoietin Acute-on-chronic liver failure THROMBOCYTOPENIA Hepatocyte growth factor PROGNOSIS 
Endoscopic submucosal dissection for esophageal precancerous lesions and early esophageal carcinoma: Analysis of efficacy and serum tumor markers
《World Journal of Gastrointestinal Surgery》2025年第4期199-206,共8页Xiao-Chen Yuan Ping Jia Tian Tian Jun Zhu Xiao-Yan Zhang 
BACKGROUND Tumor progression in patients with esophageal precancerous lesions(EPLs)or early esophageal carcinoma(EEC)is typically confined in both extent and location.Prompt and effective intervention significantly im...
关键词：Endoscopic submucosal dissection Esophageal precancerous lesions Early esophageal carcinoma Therapeutic efficacy Serum tumor markers 
Comparison of the efficacy of carbapenems and cephalosporins for postoperative treatment of perforated appendicitis in children
《World Journal of Gastrointestinal Surgery》2025年第4期244-254,共11页Tian Hang Qiao-Lin Chen Ya-Hong Li Shi-Wen Wang Xiao-Hong Jiang Wei-Chao Zhu 
Supported by Jiaxing Science and Technology Plan Project,No.2024AD30035.
BACKGROUND Pediatric perforated appendicitis(PPA)is a severe acute condition requiring surgical intervention and postoperative antibiotic therapy.Antibiotic selection differs significantly among pediatric centers,and ...
关键词：CHILDREN Perforated appendicitis Pathogenic bacteria CARBAPENEMS CEPHALOSPORINS 
Efficacy of a novel artificial liver versatile plasma purification system in patients with acute-on-chronic liver failure
《World Journal of Gastroenterology》2025年第14期83-93,共11页Zhong-Shang Dai Min Zhang Yuan-Ye Deng Ning Zhou Yi Tian 
Supported by Natural Science Foundation of Hunan Province,China,No.2022JJ30842 and No.2024JJ6560;Clinical Medical Research Center for Viral Hepatitis of Hunan Province,No.2023SK4009;Beijing iGandan Foundation,No.RGGJJ-2021-017 and No.iGandanF-1082022-RGG023.
BACKGROUND We have innovatively amalgamated membrane blood purification and centrifugal blood cell separation technologies to address the limitations of current artificial liver support(ALS)models,and develop a versat...
关键词：Acute-on-chronic liver failure Artificial liver support Versatile plasma purification system Re-hospitalization frequencies MORTALITY 
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