VANCOMYCIN

作品数：97被引量：151H指数：6
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Correlations of vancomycin trough concentration and its efficacy and toxicity in patients in the intensive care unit
《World Journal of Clinical Cases》2025年第16期18-28,共11页Teng Guo Li-Ying Du Ming-Feng Liu Xia-Jin Zhou Xin-Ran Chen 
Supported by the Key Project Plan of Health and Medical Science Research in Hebei Provincial Health Commission,No.20190745.
BACKGROUND Plasma concentration monitoring is crucial for optimizing vancomycin use,particularly in patients in the intensive care unit(ICU).However,the reference interval for vancomycin plasma concentration remains u...
关键词：VANCOMYCIN Therapeutic drug monitoring Intensive care unit Trough concentration Methicillin-resistant Staphylococcus aureus infection Area under the curve 
An injectable magnesium-coordinated phosphate chitosan-based hydrogel loaded with vancomycin for antibacterial and osteogenesis in the treatment of osteomyelitis
《Regenerative Biomaterials》2024年第6期111-124,共14页Peng Zhang Tiehua Wang Junyu Qian Haotian Qin Peng Liu Ao Xiong Anjaneyulu Udduttula Deli Wang Hui Zeng Yingqi Chen 
supported by the Natural Science Foundation of China(no.82202664);Shenzhen Key Laboratory of Orthopaedic Diseases and Biomaterials Research(no.ZDSYS20220606100602005);Guangdong Basic and Applied Basic Research Foundation(no.2023A1515012764,2021A1515220053,2022A1515220038);Sichuan Science and Technology Program(2023ZYD0115);Shenzhen Science and Technology Project(JCYJ20190809165805604,JCYJ20220818102815033,JCYJ20220531094214032),and Shenzhen High-level Hospital Construction Fund.
Microbial infections of bones,particularly after joint replacement surgery,are a common occurrence in clinical settings and often lead to osteomyelitis(OM).Unfortunately,current treatment approaches for OM are not sat...
关键词：injectable chitosan hydrogel vancomycin loading and release antibacterials property osteogenic promotive property osteomyelitis treatment 
Vancomycin-encapsulated hydrogel loaded microarc-oxidized 3D-printed porous Ti6Al4V implant for infected bone defects:Reconstruction,anti-infection,and osseointegration
《Bioactive Materials》2024年第12期18-31,共14页Teng Zhang Wenhao Zhou Wanliang Yang Jingwei Bi Hao Li Xianlei Gao Baoliang Zhang Guidong Shi Ka Li Zhijian Wei Xin Pan Shiqing Feng 
supported by the National Natural Science Foundation of China[grant number 82202729];the Natural Science Foundation of Shandong Province[grant number ZR2022QH261];the Taishan Scholar Project of Shandong Province[grant number tsqn202306355];the National Natural Science Foundation of China[grant number 32101087];the Tianjin Municipal Science and Technology Program(21JCZDJC01100).
Infected bone defect is a formidable clinical challenge.Conventional approaches to prevention and treatment for infected bone defects are unsatisfactory.The key elements of the treatment are bone defect reconstruction...
关键词：Porous Ti6Al4V implants Infected bone defects ANTI-INFECTION OSSEOINTEGRATION 
Therapeutics involved in managing initial and recurrent Clostridium difficile infection:An updated literature review
《World Journal of Gastrointestinal Pharmacology and Therapeutics》2024年第5期1-14,共14页Vignesh K Nagesh Hadrian Hoang-Vu Tran Daniel Elias Izage Kianifar Aguilar Tanni Sethi AiswaryaMenon Charlene Mansour Florchi Furman Kylie Tsotsos Talia Subar Auda Auda Aman Sidiqui JevonLamar Nikita Wadhwani Shraboni Dey Abraham Lo Adam Atoot Simcha Weissman Humberto Sifuentes Ayrton I Bangolo 
Clostridium difficile infection(CDI)has been increasing due to the effect of recurrent hospitalizations.The use of antibiotics has been shown to alter the gut microbiome and lead to CDIs.The treatment is limited to th...
关键词：Clostridium difficile ANTIBIOTICS VANCOMYCIN Fidaxomicin Prevention Bezlotoxumab Fecal microbiota transplant 
Invitro pharmacodynamicstudyof ceftobiprole,vancomycin,linezolid and daptomycin against staphylococcal bloodstream infections
《China Medical Abstracts(Internal Medicine)》2024年第2期83-84,共2页李玲琴 
Objective To evaluate the antibacterial efficacy of ceftobiprole,vancomycin,linezolid,and daptomycin against Staphylococcus aureus(SAU)and coagulasenegative Staphylococcus(CNS)bloodstream infections,which can provide ...
关键词：dosage Blood INFECTIONS 
Designing of tragacanth gum-poly [2-(methacryloyloxy) ethyl] dimethyl-(3-sulfopropyl) ammonium hydroxide and poly(acrylamide) based hydrogels for drug delivery and wound dressing applications
《Medicine in Novel Technology and Devices》2024年第2期90-101,共12页Kavita Devi Ashima Sharma Rajesh Kumar Baljit Singh 
Bioactive tragacanth gum(TG)was functionalized by covalent crosslinking of poly[2-(methacryloyloxy)ethyl]dimethyl-(3-sulfopropyl)ammonium hydroxide(PMEDSAH)to design network structure in form of hydrogel wound dressin...
关键词：Hydrogel dressings Drug delivery Wound dressings VANCOMYCIN 
Antibacterial HA-coatings on bioresorbable Mg alloy
《Journal of Magnesium and Alloys》2024年第5期1965-1985,共21页K.V.Nadaraia D.V.Mashtalyar M.A.Piatkova A.I.Pleshkova I.M.Imshinetskiy M.S.Gerasimenko E.A.Belov V.V.Kumeiko D.N.Kozyrev K.A.Fomenko V.V.Mostovaya B.R.Torpanov A.R.Biktimirov I.S.Osmushko S.L.Sinebryukhov S.V.Gnedenkov 
supported by Russian Science Foundation Grant no.22-73-10149,https://rscf.ru/project/22-73-10149/;supported by the Russian Science Foundation Grant no.23-13-00329,https://rscf.ru/project/23-13-00329/。
In this study,a calcium-phosphate coating was formed on a Mg-Mn-Ce alloy by the plasma electrolytic oxidation(PEO).The antibiotic vancomycin,widely used in the treatment of infections caused by Staphylococcus aureus(S...
关键词：Bioactive coatings BIOCOMPATIBILITY Mg alloy Plasma electrolytic oxidation Hydroxyapatite VANCOMYCIN 
Does topical vancomycin prevent fracture-related infections in closed fractures undergoing open reduction and internal fixation?A randomised controlled trial
《Chinese Journal of Traumatology》2024年第2期71-76,共6页Mohit Gandhi Gopisankar Balaji Jagdish Menon Ruben Raj Thomas 
Purpose:The role of topical vancomycin in fracture-related infection(FRI)is debatable.Very few studies have reported their efficacy in open and high-risk extremity fractures.This study aimed to assess topical vancomyc...
关键词：INFECTIONS ANTIBIOTICS VANCOMYCIN FRACTURES 
Vancomycin flushing syndrome in orthopaedic practice:A case report被引量：2
《World Journal of Orthopedics》2023年第10期771-775,共5页Fawaz M Al-Anii Mir Sadat-Ali Khalid Waleed Al-Tabash Ahmad I AlMulhim Sulaiman A AlMousa Abdulaziz M AlHawas 
BACKGROUND Vancomycin flushing syndrome(VFS),also known as red man syndrome,is an allergic reaction to vancomycin.It typically presents as a rash on the face,neck,and upper torso after intravenous administration of va...
关键词：VANCOMYCIN Anaphylactic reactions Red man syndrome Vancomycin flushing syndrome Case report 
Evaluating Vancomycin Clinical Outcomes Using Area under the Curve versus Trough Based Dosing Strategies
《Advances in Infectious Diseases》2023年第3期442-451,共10页Chelsea A. Schneider William Rodriguez Jenny Martinez William R. Wolowich 
Background: The 2020 consensus guidelines recommend AUC guided dosing as the preferred monitoring method for vancomycin. AUC based dosing has shown to reduce incidence of acute kidney injury (AKI), utilize lower daily...
关键词：AUC MRSA PHARMACOKINETICS Trough Based Dosing VANCOMYCIN 
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