ANTI-INFECTION

作品数：28被引量：67H指数：6
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Photothermal MXene-embedded tannin-Eu^(3+)particles as in situ bacterial vaccines for accelerating healing of wounds infected by seawater immersion and providing persistent anti-infection effects
《Bio-Design and Manufacturing》2025年第1期116-133,I0045-I0050,共24页Zhentao Li Ting Song Yanpeng Jiao Zijing Zhu Yang Liao Zonghua Liu 
supported by the National Key Research and Development Program of China(No.2018YFC0311103);the Project of Science and Technology Innovation Cultivation for University Students of Guangdong Province(No.pdjh202010062);the Science and Technology Project of Guangzhou City(No.2018020100);the General Program of China Postdoctoral Science Foundation(No.2021M701599);the National Natural Science Foundation of China(No.32201083);the Science and Technology Program of Heyuan,China(No.230510171473326);the Science and Technology Program of Guangzhou,China(No.2024A03J0232);the Medical Scientific Research Foundation of Guangdong Province of China(No.A2020548);the Fundamental Research Funds for the Central Universities,China(No.21623403).
The low temperature,high salt content,and bacterial composition of a seawater environment can induce severe infections in open wounds,thus impeding wound healing.To date,numerous wound dressings have been developed fo...
关键词：MXene TANNIN Wound healing ANTI-INFECTION In situ vaccine 
Vancomycin-encapsulated hydrogel loaded microarc-oxidized 3D-printed porous Ti6Al4V implant for infected bone defects:Reconstruction,anti-infection,and osseointegration
《Bioactive Materials》2024年第12期18-31,共14页Teng Zhang Wenhao Zhou Wanliang Yang Jingwei Bi Hao Li Xianlei Gao Baoliang Zhang Guidong Shi Ka Li Zhijian Wei Xin Pan Shiqing Feng 
supported by the National Natural Science Foundation of China[grant number 82202729];the Natural Science Foundation of Shandong Province[grant number ZR2022QH261];the Taishan Scholar Project of Shandong Province[grant number tsqn202306355];the National Natural Science Foundation of China[grant number 32101087];the Tianjin Municipal Science and Technology Program(21JCZDJC01100).
Infected bone defect is a formidable clinical challenge.Conventional approaches to prevention and treatment for infected bone defects are unsatisfactory.The key elements of the treatment are bone defect reconstruction...
关键词：Porous Ti6Al4V implants Infected bone defects ANTI-INFECTION OSSEOINTEGRATION 
Natural medicine can substitute antibiotics in animal husbandry:protective effects and mechanisms of rosewood essential oil against Salmonella infection被引量：1
《Chinese Journal of Natural Medicines》2024年第9期785-796,共12页WANG Lanqiao FANG Juan WANG Heng ZHANG Baoyu WANG Nan YAO Xinyu LI He QIU Jiazhang DENG Xuming LENG Bingfeng WANG Jianfeng TAN Wenxi ZHANG Qiaoling 
supported by the National Key Research and Development Program of China (No. 2021YFD1801000);the National Natural Science Foundation of China (Nos.31772798, 31970507, 81861138046, and 31902321)。
Aniba rosaeodora essential oil(RO) has been traditionally used in natural medicine as a substitute for antibiotics due to its notable antidepressant and antibacterial properties. Salmonella, a prevalent pathogen in fo...
关键词：Rosewood essential oil SALMONELLA Aniba rosaeodora Antibacterial effect ANTI-INFLAMMATION ANTI-INFECTION 
Repurposing Loperamide as an Anti-Infection Drug for the Treatment of Intracellular Bacterial Pathogens
《Engineering》2024年第8期180-193,共14页Hongtao Liu Siqi Li Le Deng Zhenxu Shi Chenxiao Jiang Jingyan Shu Yuan Liu Xuming Deng Jianfeng Wang Zhimin Guo Jiazhang Qiu 
supported by the National Key Research and Development Program of China(2021YFD1801000);the Natural Science Foundation of China(32373066);the Natural Science Foundation of Jilin Province(20230101142JC);the Fundamental Research Funds for the Central Universities.
Infections caused by intracellular bacterial pathogens are difficult to treat since most antibiotics have low cell permeability and undergo rapid degradation within cells.The rapid development and dissemination of ant...
关键词：Intracellular bacteria US Food and Drug Administration(FDA)-approved drugs Drug repurposing LOPERAMIDE AUTOPHAGY Glycoprotein nonmetastatic melanoma protein B 
Bioinspired super-hydrophilic zwitterionic polymer armor combats thrombosis and infection of vascular catheters
《Bioactive Materials》2024年第7期493-504,共12页You Ke Haotian Meng Zeyu Du Wentai Zhang Qing Ma Yuting Huang Linxian Cui Yifeng Lei Zhilu Yang 
supported by the National Natural Science Foundation of China (Project 82072072,32261160372,32171326,32371377);the Guangdong Basic and Applied Basic Research Foundation (2022B1515130010,2021A1515111035);Dongguan Science and Technology of Social Development Program (20231800906311,20231800900332).
Thrombosis and infection are two major complications associated with central venous catheters(CVCs),which significantly contribute to morbidity and mortality.Antifouling coating strategies currently represent an effic...
关键词：ANTI-INFECTION ANTITHROMBOSIS Phenol-polyamine SUPER-HYDROPHILICITY Zwitterionic polymers 
Self-assembly multifunctional DNA tetrahedron for efficient elimination of antibiotic-resistant bacteria
《Aggregate》2024年第1期204-215,共12页Tiantian Wu Yu Fu Shuang Guo Yanqiang Shi Yuxin Zhang Zhijin Fan Bin Yang Baoquan Ding Yuhui Liao 
National Key R&D Program of China,Grant/Award Numbers:2021YFA1200302,2021YFC2302200,2018YFA0208900;National Natural Science Foundation of China,Grant/Award Numbers:22025201,22077023,82202532,82272248,82002244,81972019;Natural Science Fund of Guangdong Province for Distinguished Young Scholars,Grant/Award Number:2022B1515020089;China Postdoctoral Science Foundation,Grant/Award Numbers:2022M711528,2021M691428。
Antibiotic resistance is a major challenge in the clinical treatment of bacterial infectious diseases.Herein,we constructed a multifunctional DNA nanoplatform as a versatile carrier for bacteria-specific delivery of c...
关键词：antibiotic resistance anti-infection therapy BIOFILM DNA nanotechnology targeted delivery 
Review on carbon dots:Synthesis and application in biology field
《BMEMat(BioMedical Engineering Materials)》2023年第4期65-93,共29页Xueting Li Lidong Yu Mingyue He Ce Chen Zewen Yu Shanshan Jiang Yi Wang Li Li Bingsheng Li Guixue Wang Aidong Shen Jianglin Fan 
Innovation Team Program of Guangdong Province,Grant/Award Number:2020KCXTD038;Key Technologies Research and Development Program,Grant/Award Number:2019YFA0705202;National Natural Science Foundation of China,Grant/Award Numbers:12032007,31701296,62274027,81941001;Chongqing Natural Science Foundation,Grant/Award Number:cstc2019jcyjzdxmX0028。
As a multifunctional fluorescent nanomaterial, carbon dots (CDs) not only have small size, stable chemical properties, excellent photoluminescence characteristics, but also exhibit good biocompatibility and low toxici...
关键词：anti-COVID-19 ANTI-INFECTION antioxidant BIOIMAGING biosensor carbon dots drug/gene/protein delivery metal detection PDT/PTT self-function subcellular localization 
Anti-infection effects of heparin on SARS-CoV-2 in a diabetic mouse model被引量：2
《Zoological Research》2023年第6期1003-1014,共12页Zhongyun Zhang Ning Zhang Xuancheng Lu Min Zhou Xiaoxiang Yan Weiqiong Gu Jingru Yang Qin Zhang Cheng Zhang Yuhuan Gong Mingjun Jia Xiaoyu Zhang Peng Ning Mei Liu Xiaoyan Li Xiaomeng Shi Wenjun Liu George FGao Guang Ning Jiqiu Wang Yuhai Bi 
supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (CAS) (XDB29010102);National Natural Science Foundation of China (NSFC) (91957124,82161148010,32041010);Self-supporting Program of Guangzhou Laboratory (SRPG22-001);National Science and Technology Infrastructure of China (National Pathogen Resource Center-NPRC-32);Management Strategy of the Tertiary Prevention and Treatment of Diabetes Based on DIP system (supported by China Health Promotion Foundation);supported by the Youth Innovation Promotion Association of CAS (Y2021034);Innovation Team and Talents Cultivation Program of the National Administration of Traditional Chinese Medicine (ZYYCXTD-D-202208)。
Severe acute respiratory syndrome coronavirus 2(SARSCo V-2)infection can result in more severe syndromes and poorer outcomes in patients with diabetes and obesity.However,the precise mechanisms responsible for the com...
关键词：SARS-CoV-2 DIABETES Mouse model HEPARIN Antiviral therapy 
Antimicrobial-free knitted fabric as wound dressing and the mechanism of promoting infected wound healing被引量：3
《Science China(Technological Sciences)》2023年第7期2147-2154,共8页ZHANG Huan WAN HuaKun HU XiuYuan ZHAO QingHua LU JianGuo WANG Dong LU ZhenTan 
supported by the National Natural Science Foundation of China (Grant No.51703169)。
Fibrous biomaterials are widely used in the design and fabrication of antibacterial wound dressings.Two strategies are used to make anti-infective dressings:antibacterial and probiotic therapies,which have potential b...
关键词：ANTI-INFECTION bacterial adhesion healing mechanism knitted fabric wound dressing 
Postpartum ovarian vein thrombosis after cesarean section and vaginal delivery:Two case reports被引量：1
《World Journal of Clinical Cases》2023年第16期3877-3884,共8页Hong-Dan Zhu Wei Shen He-Li Wu Xia Sang Yun Chen Li-Shu Geng Tao Zhou 
BACKGROUND Postpartum ovarian vein thrombosis(POVT)is a rare puerperal complication.It is easily missed or misdiagnosed due to its insidious onset and lack of specific clinical symptoms and signs.This paper reports tw...
关键词：Postpartum ovarian vein thrombosis Computed tomography ANTICOAGULATION ANTI-INFECTION Case report 
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