云南高校图书馆联盟文献共享服务平台- LOPERAMIDE

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Repurposing Loperamide as an Anti-Infection Drug for the Treatment of Intracellular Bacterial Pathogens: 《Engineering》2024年第8期180-193,共14页Hongtao Liu Siqi Li Le Deng Zhenxu Shi Chenxiao Jiang Jingyan Shu Yuan Liu Xuming Deng Jianfeng Wang Zhimin Guo Jiazhang Qiu; supported by the National Key Research and Development Program of China(2021YFD1801000);the Natural Science Foundation of China(32373066);the Natural Science Foundation of Jilin Province(20230101142JC);the Fundamental Research Funds for the Central Universities.; Infections caused by intracellular bacterial pathogens are difficult to treat since most antibiotics have low cell permeability and undergo rapid degradation within cells.The rapid development and dissemination of ant...; 关键词：Intracellular bacteria US Food and Drug Administration(FDA)-approved drugs Drug repurposing LOPERAMIDE AUTOPHAGY Glycoprotein nonmetastatic melanoma protein B

Preventive effect of kiwi berry(Actinidia arguta)on loperamide-induced constipation被引量：1: 《Food Science and Human Wellness》2024年第3期1410-1421,共12页Jiyue Zhang Bin Li Ningxuan Gao Haikun Li Xingyue Cui Hanqian Jiang Siyi Tang Chenyu Jin Jinlong Tian; financially supported by National Natural Science Foundation of China (U21A20273);China Agriculture Research System of MOF and MARA (CARS-29);the First Batch of Liaoning“Unveiling Leader”Scientific and Technological Projects (2021JH1/10400036)。; Constipation is a common intestinal disease.Kiwi berries can effectively prevent constipation.However,studies have yet to be done to determine how kiwi berries prevent constipation.For two weeks,mice in this study wer...; 关键词：Kiwi berry CONSTIPATION VIP-cAMP-PKA-AQP3 Gut microbiota

Hetong decoction(和通汤)relieves loperamide-induced constipation in rats by regulating expression of aquaporins被引量：1: 《Journal of Traditional Chinese Medicine》2023年第6期1160-1167,共8页HUANG Xi XIA Youguang HAN Kai QI Weiwei LINGHU Qing ZHANG Qing XUE Jingbo; OBJECTIVE:To investigate whether Hetong decoction(和通汤,HTT)alleviates constipation via regulating AQPs expression.METHODS:Constipation in rats was induced by loperamide,and rats were randomly assigned into model(sal...; 关键词：AQUAPORINS CONSTIPATION hetong decoction LOPERAMIDE

The effect of kiwi berry(Actinidia arguta)on preventing and alleviating loperamide-induced constipation: 《Food Innovation and Advances》2023年第1期1-8,共8页Jiyue Zhang Dongnan Li Qilin Tian Yumeng Ding Hanqian Jiang Guang Xin Shunchang Cheng Siyi Tang Chenyu Jin Jinlong Tian Bin Li; The First Batch of Liaoning'Unveiling Leader'Scientific and Technological Projects(2021JH1/10400036);China Agriculture Research System of MOF and MARA(CARS-29);Liaoning Province food processing chief science and technology special commissioner(2022JH5/10400125)。; This research aimed to study the preventive and relieving outcomes of kiwi berry on constipation.The administration of kiwi berries to mice resulted in a significant increase in body weight gain of 148.2%compared to m...; 关键词：CONSTIPATION PREVENTION COLON

Systematically optimized topical delivery system for Loperamide hydrochloride: Formulation design,in vitro and in vivo biopharmaceutical evaluation: 《Asian Journal of Pharmaceutical Sciences》2018年第3期255-264,共10页Jianhui Shu Jingjing Zhao Fang Guo; This study aimed to develop a suitable topical delivery system containing diethylene glycol monoethyl ether(DGME) for Loperamide hydrochloride(Lop). Two factors, three levels CentralComposite design were applied by ge...; 关键词：LOPERAMIDE HYDROCHLORIDE TOPICAL delivery Skin retention In vitro–in VIVO correlation

Torsades de Pointes Secondary to Excessive Loperamide Use: 《Journal of Pharmacy and Pharmacology》2016年第7期322-327,共6页Joseph S. Van Tuylt Gail Brock Kristen Bova Campbell Sana M. Al-Khatib; Abstract： Loperamide is a common, over-the-counter, antidiarrheal medication that has been implicated in cases of ventricular tachycardia. A 32 year-old female patient with a history of opioid abuse and no prior hist...; 关键词：Torsades de pointes LOPERAMIDE QT prolongation.

Antidiarrheal effects of hydromethanolic extract of Combretum dolichopetalum leaves in mice: 《Journal of Coastal Life Medicine》2015年第11期910-913,共4页Samuel Okwudili Onoja Nkeiruka Emmanuela Udeh; Objective:To evaluate the antidiarrheal activity of the hydromethanolic extract of Combretum dolichopetalum(C.dolichopetalum)leaves.Methods:The antidiarrheal activity of the hydromethanolic extract of C.dolichopetalum...; 关键词：ANTIDIARRHEAL LOPERAMIDE Castor oil Charcoal meal Enteropooling

Conservative treatment for anal incontinence: 《Gastroenterology Report》2014年第2期85-91,共7页Dan Carter; Anal incontinence(AI)in adults is a troublesome condition that negatively impacts upon quality of life and results in significant embarrassment and social isolation.The conservative management of AI is the first step ...; 关键词：anal incontinence LOPERAMIDE BIOFEEDBACK

Studies on the anti-diarrheal properties of leaf extract of Desmodium puchellum被引量：1: 《Asian Pacific Journal of Tropical Biomedicine》2013年第8期639-643,共5页Md.Khalilur Rahman Soumitra Barua Md.Fokhrul Islam Md.Rafikul Islam Mohammed Abu Sayeed Mst.Shahnaj Parvin Md.EkramulIslam; Financially supported by the Bangladesh Council of Scientific and Industrial Research(BCSIR),Chittagong(Grant No.1217); Objective:To evaluate the pharmacological activity against diarrhea of methanol and petroleum ether extract ofDesmodium puchellum(Family:Fabaceae)leaves.Methods:The extract was evaluated for castor oil-induced diarrhe...; 关键词：Antidiarrhea THROMBOLYSIS DESMODIUM puchellum LOPERAMIDE

Opiate-induced constipation related to activation of small intestine opioid μ2-receptors被引量：20: 《World Journal of Gastroenterology》2012年第12期1391-1396,共6页Wency Chen Hsien-Hui Chung Juei-Tang Cheng; Supported by A grant from E-Da Hospital (in part); AIM： To investigate the role of opioid p-receptor subtype in opiate-induced constipation （OIC）.METHODS： The effect of Ioperamide on intestinal transit was investigated in mice. Ileum strips were isolated from 12-w...; 关键词：ATP-sensitive K^＋ channels Isometric tension LOPERAMIDE Opioid p-receptors Small intestine

LOPERAMIDE