HUMORAL

作品数:84被引量:142H指数:6
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相关领域:医药卫生更多>>
相关作者:施节娟邓迺封吕国义贺平郭亚军更多>>
相关机构:第四军医大学天津医科大学第二军医大学更多>>
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相关基金:国家自然科学基金卫生部科学研究基金国家重点基础研究发展计划天津市自然科学基金更多>>
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Double-metal ion adjuvant stabilized Pickering emulsion to amplify humoral and cellular immune responses
《Nano Research》2025年第3期360-371,共12页Zhaofei Guo Fuhua Wu Yanhua Xu Xue Tang Xiejin Xie Rui Hu Yangsen Ou Hongjiao Wei Lin Ye Chunting He Penghui He Hairui Wang Guangsheng Du Xun Sun 
supported by the National Key Research and Development Program of China(No.2023YFC2307700);the National Natural Science Foundation of China(Nos.U24A20811 and 82341038);the Program Sichuan Veterinary Medicine and Drug Innovation Group of China Agricultural Research System(No.SCCXTD-2025-18);the 111 project(No.B18035);the Fundamental Research Funds for the Central Universities.
Metal ions play critical roles in many immune processes,and their modulation may open up new forms of vaccine adjuvants.Current vaccines predominantly utilize aluminum salts as adjuvants,but alum has poor ability to i...
关键词:Pickering nanoemulsion bimetallic adjuvant cGAS-STING vaccine 
DNA vaccine prime and replicating vaccinia vaccine boost induce robust humoral and cellular immune responses against MERS-CoV in mice
《Virologica Sinica》2024年第3期490-500,共11页Xiuli Shen Shuhui Wang Yanling Hao Yuyu Fu Li Ren Dan Li Wenqi Tang Jing Li Ran Chen Meiling Zhu Shuo Wang Ying Liu Yiming Shao 
financially supported by National Nature Science Foundation of China(U20A20362);the Subject of SKLID(2020SKLID102).
As of December 2022,2603 laboratory-identified Middle East respiratory syndrome coronavirus(MERS-CoV)infections and 935 associated deaths,with a mortality rate of 36%,had been reported to the World Health Organization...
关键词:MERS-CoV VTT vaccine DNA vaccine Humoral and cellular immune responses Prime/boost strategy 
Humoral and cellular immunity against diverse SARS-CoV-2 variants
《Journal of Genetics and Genomics》2023年第12期934-947,共14页Changxu Chen Xin Wang Zeli Zhang 
Since the outbreak of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in late 2019, the virus has rapidly spread worldwide. This has led to an unprecedented ...
关键词:SARS-CoV-2 COVID-19 Vaccines Humoral immunity Cellular immunity 
Monitoring humoral and cellular immunity over 6 months after mRNA-based bivalent COVID-19 vaccine administration
《Infectious Diseases Research》2023年第4期22-23,共2页Laura Pighi Brandon MHenry Simone De Nitto Gian Luca Salvagno Giuseppe Lippi 
Dear Editor,Although the World Health Organization(WHO)has declared an end to the global emergency for coronavirus disease 2019(COVID-19)[1],the clinical burden of severe acute respiratory syndrome coronavirus disease...
关键词:immunity acute sided 
The recombinant truncated envelope protein of West Nile virus adjuvanted with Alum/CpG induces potent humoral and T cell immunity in mice
《Biosafety and Health》2023年第5期300-307,共8页Yongping Du Yao Deng Ying Zhan Ren Yang Jiao Ren Wen Wang Baoying Huang Wenjie Tan 
the National Key Research and Development Program of China(2022YFC2304100,2022YFC2303401,2016YFD0500301).
West Nile virus(WNV)is a mosquito-transmitted flavivirus distributed globally for decades and can cause disease in humans and animals.So far,no WNV vaccine has been licensed for human use.Therefore,the development of ...
关键词:West Nile virus Envelope protein Vaccine Alum/CpG adjuvant Immunity 
Immunosuppressive therapy selectively modulates B-cell responses in patients with rheumatic and musculoskeletal diseases receiving the inactivated COVID-19 vaccine
《Rheumatology & Autoimmunity》2023年第2期78-89,共12页Rui Li Ruru Guo Jia Li Bing Zheng Ronghao Xu Xiaoyue Jiang Yingying Chen Guo Tang Qianqian Li Yixuan Li Jiaqi Feng Xiaoxiang Chen Ying Wang Shuang Ye Fang Du Liangjing Lu Jun Deng 
National Natural Science Foundation of China,Grant/Award Numbers:82271784,81974251,82071816;National Key Research and Development Program of China,Grant/Award Number:2017YFC0909002。
Background:Immunosuppressive medication reduces the immunogenicity of the coronavirus disease 2019(COVID-19)vaccines in patients with rheumatic and musculoskeletal diseases(RMDs).However,the underlying mechanism remai...
关键词:COVID-19 vaccination humoral and cellular responses immunosuppressive medication rheumatic and musculoskeletal diseases 
Gut microbiota as a potential key to modulating humoral immunogenicity of new platform COVID-19 vaccines
《Signal Transduction and Targeted Therapy》2023年第6期2447-2450,共4页Hye Seong Bo Kyu Choi Young-Hee Han Jun Hyoung Kim Jeong-An Gim Sooyeon Lim Ji Yun Noh Hee Jin Cheong Woo Joo Kim Joon Young Song 
Dear Editor,Coronavirus disease 2019(COVID-19)is a novel respiratory infectious disease,caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),which led to a global pandemic.Although vaccination is the ...
关键词:vaccines RESPIRATORY ACUTE 
Retrospective Analysis of External Quality Assessment Data of Humoral (Except Feces) Morphology in Guangxi from 2010 to 2022
《Medicinal Plant》2023年第2期107-112,共6页Ciying XIAO Xiaochun LIU Juan TANG Hongying ZHAO Xiangyang ZHOU Shengzhou NONG 
Supported by the Scientific Research Project of Guangxi Health Commission (Z2014221)。
[Objectives] The study aims to improve the ability of inspectors to recognize humoral morphology and provide data reference for the improvement of EQA work of humoral morphology by Guangxi Clinical Laboratory Center. ...
关键词:Humoral morphology External quality assessment Retrospective analysis 
Weakened humoral and cellular immune response to the inactivated COVID-19 vaccines in Chinese individuals with obesity/overweight被引量:1
《Genes & Diseases》2023年第2期608-617,共10页Qian Zhu Yingzhi Zhang Juan Kang Zhiwei Chen Mingli Peng Min Chen Gaoli Zhang Dejuan Xiang Shuang Xiao Hu Li Ying Mei Jie Yang Xiaoya Qi Dachuan Cai Hong Ren 
supported by the National Science and Technology Major Project of China(No.2017ZX10202203-007,No.2017ZX10202203-008,and No.2018ZX10302206-003);a pilot project of clinical cooperation between traditional Chinese and western medicine for significant and complicated diseases of National Administration of Traditional Chinese Medicine:hepatic fibrosis.We also acknowledge the support of the National Natural Science Foundation of China(No.81772198);the Natural Science Foundation of Chongqing,China(No.cstc2020jcyj-msxmX0389);General Project of Chongqing Natural Science Foundation(No.cstc2020jcyj-msxmX0015).
Inactivated COVID-19 vaccines have been widely used to vaccinate the Chinese population.However,limited literature exists to explore the effect of obesity on the humoral and cellular immune response to these vaccines....
关键词:COVID-19 Immune response Inactivated vaccine OBESITY OVERWEIGHT 
An inactivated recombinant rabies virus chimerically expressed RBD induces humoral and cellular immunity against SARS-CoV-2 and RABV被引量:2
《Virologica Sinica》2023年第2期244-256,共13页Haili Zhang Hongli Jin Feihu Yan Yumeng Song Jiaxin Dai Cuicui Jiao Yujie Bai Jingxuan Sun Di Liu Shen Wang Mengyao Zhang Jilong Lu Jingbo Huang Pei Huang Yuanyuan Li Xianzhu Xia Hualei Wang 
funded by the National Key Research and Development Program of China(grant No.2021YFC2600202);the National Natural Science Foundation of China(grant numbers 31872487).
Many studies suggest that severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)can infect various animals and transmit among animals,and even to humans,posing a threat to humans and animals.There is an urgent ne...
关键词:SARS-CoV-2 Vaccine RBD Chimeric expression RABV 
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