Metal-free C(sp^(2))-H perfluoroalkylsulfonylation and configuration inversion:Stereoselective synthesis ofα-perfluoroalkylsulfonyl E-enaminones  

作　　者：Qing Yu Yunyun Liu Jie-Ping Wan 

机构地区：[1]College of Chemistry and Chemical Engineering,Jiangxi Normal University,Nanchang 330022,China

出　　处：《Chinese Chemical Letters》2021年第11期3514-3517,共4页中国化学快报（英文版）

基　　金：financially supported by National Natural Science Foundation of China(No.21861019);Natural Science Foundation of Jiangxi Province(No.20202ACBL203006).

摘　　要：The perfluoroalkylsulfonylation(CF_(3)SO_(2),C_(2)F_(5)SO_(2)and CHF_(2)SO_(2))in the enaminone C-H bonds has been developed simply via the promotion of molecular iodine by using stable and cheap sodium perfluoroalkyl sulfinates as coupling partners.The stereoselective synthesis of E-configuratedα-perfluoroalkylsulfonyl enaminones has been realized via unprecedented C-H bond elaboration and C=C double bond configuration inversion by free radical process.

关 键 词：C-H Functionalization ENAMINONE Perfluoroalkyl sulfonylation METAL-FREE Configuration inversion 

分 类 号：O621.25[理学—有机化学]