24小时连续眼压测量技术及进展  

Techniques and progress of 24-hour intraocular pressure measurement

作　　者：张宇宁 杨扬帆[1] 余敏斌[1] Zhang Yuning;Yang Yangfan;Yu Minbin(Zhongshan Ophthalmic Center,Sun Yat-Sen University,State Key Laboratory of Ophthalmology,Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science,Guangzhou 510060,China)

机构地区：[1]中山大学中山眼科中心眼科学国家重点实验室广东省眼科视觉科学重点实验室,广州510060

出　　处：《国际眼科纵览》2021年第6期465-470,共6页International Review of Ophthalmology

基　　金：载人航天领域预先研究项目(020105);香港创新及科技基金(MRP/039/18X)。

摘　　要：眼压具有昼夜波动性和节律性,24小时眼压对青光眼的诊断、治疗和疗效评价均有重要意义。临床上依靠眼压计多次测量完成的24小时眼压测量是间断的,不能准确地反映眼压变化情况。植入式眼压测量技术包括单纯植入式和复合植入式,通过将压力传感器直接植入眼内,实现长期或永久的眼压监测。角膜接触镜式眼压测量技术是在角膜接触镜内嵌入传感器,通过感知眼压变化引起的角膜形变以进行24小时连续眼压监测。连续眼压测量技术在研究眼压变化规律、辅助青光眼的诊断和治疗等方面具有良好的应用前景。Intraocular pressure(IOP)has a fluctuation and circadian rhythm.Twenty-four-hour IOP is significant for the diagnosis,treatment and therapeutic assessment of glaucoma.In the clinic 24-hour IOP measurement via multiple IOP measurements by tonometers,fails to capture the true information of dynamic IOP.Implant tonometry consists of simple implant tonometry and compound implant tonometry,with a pressure sensor directly implanted in the eye to realize long-term or permanent IOP monitoring.Contact lens tonometry could monitor 24-hour IOP continuously by means of contact lenses inserted with a sensor that can detect corneal deformation related to IOP changes.Continuous tonometry shows a bright application prospect in studying the changes of IOP,and assisting in the diagnosis and therapeutic decision-making of glaucoma.

关 键 词：青光眼 眼压 眼压监测 传感器 

分 类 号：R775.1[医药卫生—眼科]