孕早期抑郁状况发生的影响因素分析  

Analysis of influencing factors of depression in early pregnancy

作　　者：陈淼[1] 孙静[1] 王纯[1] 吴江平[2] 王苏立[2] CHEN Miao;SUN Jing;WANG Chun;WU Jiang Ping;WANG Su Li(The Affiliated Brain Hospital of Nanjing Medical University,Nanjing 210029,Jiangsu Province,China;Nanjing Maternity and Child Health Care Hospital,Nanjing 210000,Jiangsu Province,China)

机构地区：[1]南京医科大学附属脑科医院,江苏南京210029 [2]南京市妇幼保健院,江苏南京210000

出　　处：《中国妇幼卫生杂志》2021年第6期29-33,共5页Chinese Journal of Women and Children Health

基　　金：南京市卫生科技发展专项资金项目——基于互联网平台的孕产期抑郁早期筛查与干预(YKK18112)。

摘　　要：目的探讨孕早期抑郁状况发生的影响因素。方法通过病例对照研究,选择2019年6月—2020年6月在江苏省南京市妇幼保健医院建卡就诊的孕早期女性作为研究对象,共纳入200例抑郁状态孕妇及200例健康孕妇。通过二分类logistic回归分析孕妇的年龄、孕前工作状态、学历、居住情况、家庭人均年收入、意外怀孕、流产史、头胎、人工辅助生殖等指标是否为孕早期抑郁发生的影响因素。结果居住情况、意外怀孕和家庭人均年收入可能为孕早期抑郁发生的影响因素。夫妻共居(OR=0.524,P=0.004,95%CI:0.338~0.813),意外怀孕(OR=2.068,P=0.002,95%CI:1.312~3.260),中等收入或高收入(OR=2.633,P=0.004,95%CI:1.370~5.061;OR=2.362,P=0.005,95%CI:1.294~4.310)是抑郁发生的可能影响因素。结论夫妻共同居住、充分的家庭社会支持和避免意外怀孕有助于减少孕早期抑郁发生。Objective To explore the factors in relation to depression in early pregnancy.Methods Totally 200 pregnant women with depression and 200 healthy pregnant women were recruited during early pregnancy at Nanjing Maternity and Child Health Care Hospital from June 2019 to June 2020 through a case-control study.Binary logistic regression was used to analyze the factors in relation to depression in early pregnancy,including the age of pregnant women,pre-pregnancy working status,educational background,living conditions,annual per capita household income,unplanned pregnancy,history of abortion,primary parturient,and history of artificial assisted reproduction.Results Living conditions,unplanned pregnancy and annual per capita household income might affect early pregnancy depression.Couple living together(OR=0.524,P=0.004,95%CI:0.338-0.813),unplanned pregnancy(OR=2.068,P=0.002,95%CI:1.312-3.260),high-income or middle-income pregnant women(OR=2.633,P=0.004,95%CI:1.370-5.061;OR=2.362,P=0.005,95%CI:1.294-4.310)were the influencing factors of early pregnancy depression.Conclusion Couple living together,adequate family and social support,and avoiding unplanned pregnancy may be beneficial to reduce depression in early pregnancy.

关 键 词：孕早期 抑郁 影响因素 

分 类 号：R749.4[医药卫生—神经病学与精神病学]