颅内动脉延长扩张症与脑小血管病  

Intracranial arterial dolichoectasia and cerebral small vessel disease

作　　者：王爽 张敏[2] 马阳 恽文伟[2] Wang Shuang;Zhang Min;Ma Yang;Yun Wenwei(Graduate School of Dalian Medical University,Dalian 116044,China;Department of Neurology,Changzhou Second People's Hospital Affiliated to Nanjing Medical University,Changzhou 213003,China)

机构地区：[1]大连医科大学研究生院,大连116044 [2]南京医科大学附属常州市第二人民医院神经内科,常州213003

出　　处：《国际脑血管病杂志》2021年第11期859-863,共5页International Journal of Cerebrovascular Diseases

基　　金：江苏省卫生健康委面上项目(H2019051);常州市卫生健康青苗人才培养工程(CZQM2020073)。

摘　　要：颅内动脉延长扩张症(intracranial arterial dolichoectasia,IADE)又称扩张性脑动脉病,是多种原因导致病变动脉延长、膨大及迂曲的一类疾病。脑小血管病(cerebral small vessel disease,CSVD)是指各种病因影响脑内小动脉、小静脉和毛细血管所导致的一系列临床、影像和病理综合征,其主要影像学表现包括腔隙性梗死、脑微出血、血管周围间隙扩大、脑白质高信号和脑萎缩。近年来,越来越多的研究表明IADE与CSVD的发生和发展密切相关。文章就IADE与CSVD的相关性进行了综述。Intracranial arterial dolichoectasia(IADE),also known as dilated cerebral artery disease,is a kind of disease in which the diseased arteries are lengthened,enlarged,and tortuous due to various reasons.Cerebral small vessel disease(CSVD)refers to a series of clinical,imaging and pathological syndromes caused by various etiologies affecting cerebral arterioles,venules and capillaries.Its main imaging manifestations include lacunar infarction,cerebral microbleeds,enlargement of perivascular space,white matter hyperintensities,and brain atrophy.In recent years,more and more studies have shown that IADE is closely associated with the occurrence and development of CSVD.This article reviews the correlation between IADE and CSVD.

关 键 词：脑动脉疾病 扩张 病理性 脑小血管疾病 磁共振成像 

分 类 号：R743[医药卫生—神经病学与精神病学]