语义性痴呆患者的汉语阅读特征研究  

A study of Chinese reading characteristics of patients with semantic dementia

作　　者：汤乐 陈科良 郭起浩 郁金泰 Tang Le;Chen Keliang;Guo Qihao;Yu Jintai(Department of Neurology y Huashan Hospital Affiliated to Fudan University,Shanghai,200040,P.R.China;Department of Neurology,Huadong Hospital Affiliated to Fudan University,Shanghai,200040,P.R.China;Department of Gerontology,Sixth People's Hospital Affiliated to Shanghai Jiaotong University,Shanghai,200233,P.R.China)

机构地区：[1]复旦大学附属华山医院神经内科,上海200040 [2]复旦大学附属华东医院神经内科,上海200040 [3]上海交通大学附属第六人民医院老年科,上海200233

出　　处：《老年医学与保健》2022年第1期98-102,共5页Geriatrics & Health Care

摘　　要：目的探讨语义性痴呆(semantic dementia,SD)患者的汉语阅读特征。方法选取2017年5月—2018年8月在复旦大学附属华山医院神经内科记忆门诊就诊的SD患者21例(设为SD组),另招募年龄、性别和受教育程度相匹配的体检健康者21名(设为对照组)。对2组受试者均进行Boston命名测验(Boston naming test,BNT)、动物范畴词语流畅性测验(animal fluency test,AFT)以及基于汉字特征编制的汉语词汇阅读测试(Chinese character/vocabulary reading test),并对检测结果进行比较和分析。结果 SD组BNT和AFT得分明显低于对照组(P<0.05)。SD组汉语词汇阅读测试中的汉字阅读、词汇阅读、非词阅读、真假词判断、真假字判断、听觉字形判断、视觉音素判断、同义词判断、渐进字猜读和词汇复述得分均明显低于对照组(P<0.05),而非词复述、数字联系判断、汉字延迟抄写和假字延迟抄写得分与对照组的差异均无统计学意义(P> 0.05)。结论 SD患者存在显著的汉语阅读障碍,其汉字及词汇的形、音、义识别功能均较正常对照组明显受损,而复述、数字及抄写功能相对完好。Objective To explore the Chinese reading characteristics of patients with semantic dementia(SD).Methods 21 SD patients(SD group)treated in Huashan Hospital Affiliated to Fudan University from May2017 to August2018 were selected. In addition, 21 healthy subjects(control group)with matched age,gender and education level were recruited. All subjects of both groups were tested with Boston Naming Test(BNT),Animal Fluency Test(AFT)and Chinese Character/Vocabulary Reading Test based on Chinese character characteristics. The test results of the two groups were compared and analyzed. Results The BNT and AFT scores of the SD group were significantly lower than those of the control group(P< 0.05). The scores of Chinese character reading,vocabulary reading,non-word reading,true and false word decision,true and false character decision,auditory font decision,visual phoneme decision,synonym decision,progressive word guessing and word repetition of the SD group were significantly lower than those of the control group(P< 0.05),but there was no significant difference in the scores of non-word repetition,numerical connection decision,delayed transcription of Chinese characters and delayed transcription of false characters compared with the control group(P> 0.05). Conclusion SD patients have significant Chinese dyslexia,and their recognition functions of shape,sound and meaning of Chinese characters and vocabulary are significantly impaired compared with those of healthy people,but the functions of repetition,number and transcription are relatively intact.

关 键 词：语义性痴呆 汉字 阅读 阅读障碍 

分 类 号：R749.1[医药卫生—神经病学与精神病学]