胆囊肿瘤性息肉病变的临床、影像学特征  

The clinical and imaging features of gallbladder neoplastic polyposis

作　　者：林侃如 陆伟辉 贺华 沈卫星 王庆 Lin Kanru

机构地区：[1]复旦大学附属中山医院青浦分院,201700

出　　处：《浙江临床医学》2022年第2期192-194,共3页Zhejiang Clinical Medical Journal

基　　金：上海市青浦区卫生健康委员会科研支持项目(w2019-03)。

摘　　要：目的探讨胆囊肿瘤性息肉病变的临床和影像学特征及危险因素分析。方法回顾性收集行手术治疗的胆囊息肉样病变患者500例,根据病理诊断结果分为肿瘤性息肉组(91例)和非肿瘤性息肉组(409例)。分析比较两组患者的临床资料、实验室指标及影像学特征,采用logistic回归分析胆囊肿瘤性息肉病变的影响因素。结果两组患者的年龄、息肉大小、息肉数目比较,差异有统计学意义(P<0.05)肿瘤性息肉组患者的CHOL、TG、LDL-C水平明显高于非肿瘤性息肉组(P<0.05)。SI-T曲线呈廓清型者多数为肿瘤性息肉,少数为非肿瘤性息肉,差异有统计学意义(P<0.05)。SI-T曲线呈平台型和上升型者多数为非肿瘤性息肉,少数为肿瘤性息肉,差异有统计学意义(P<0.05)。肿瘤性息肉组和非肿瘤性息肉组到达峰值时间、最大强化程度和最快强化率的差异存在统计学意义(P<0.05)。结论年龄≥60岁、息肉≥1cm、单发息肉、CHOL、TG、LDL-C、SI-T曲线呈廓清型、到达峰值时间、最大强化程度和最快强化率是胆囊肿瘤性息肉病变的独立危险因素,而SI-T曲线平台型是肿瘤性息肉的保护因素。Objective To investigate the clinical and imaging feauires and risk factors of gallbladder neoplastic polyposis.Methods Retrospectively collected line of surgical treatment of 500 patients with with polypoid lesions of gallbladder,according to pathological diagnosis,they were divided into neoplastic polyp group(91 cases)and non-neoplastic polyp group(409 cases).Compare two groups of patients with clinical data and laboratory indexes and imaging features and use logistic regression analysis to investigate the influence factors of the gallbladder neoplastic polyposis.Results There were significant differences in age,polyp size and polyp number between the two groups(P<0.05).The levels of CHOL,TG and LDL-C in neoplastic polyp group were significantly higher than those in non-neoplastic polyp group(P<0.05).Most of the patients with clearance SI-T curve were neoplastic polyps and a few were non-neoplastic polyps,and the difference was statistically significant(P<0.05).Most of the patients with plateau SI-T curve and rising SI-T curve were non-neoplastic polyps and a few were neoplastic polyps,and the difference was statistically significant(P<0.05).There were significant difterences in peak time,maximum enhancement degree and fastest enhancement rate between neoplastic polyp group and non-neoplastic polyp group(P<0.05).Conclusion Age ≥60 years old,polyp ≥1 cm,single polyp,CHOL,TG,LDL-C,SI-T curve showed clearance type,peak time,maximum enhancement degree and fastest enhancement rate are independent risk factors of gallbladder neoplastic polyp,while SI-T curve platform type is the protective factor of neoplastic polyp.

关 键 词：胆囊息肉样病变 肿瘤性息肉 影像学特征 危险因素 SI-T曲线 

分 类 号：R73[医药卫生—肿瘤]