腔内超声引导的经支气管镜针吸活检联合现场细胞学评价在肺癌患者中的诊断价值  

Evaluation of the diagnostic value of endobronchial ultrasound-guided transbronchial needle aspiration combined with rapid on-site evaluation for lung cancer

作　　者：刘勇[1] 刘岩[1] 李广 LIU Yong;LIU Yan;LI Guang(Department of Respiratory and Critical Care Medicine,Zhoukou Central Hospital,Zhoukou 466100,He’nan,China)

机构地区：[1]周口市中心医院呼吸与危重症医学科,河南周口466100

出　　处：《癌症进展》2021年第24期2544-2547,共4页Oncology Progress

基　　金：2019年度院级医学科技攻关计划项目(20190102)。

摘　　要：目的探讨腔内超声引导的经支气管镜针吸活检(EBUS-TBNA)联合现场细胞学评价(ROSE)在肺癌患者中的诊断价值。方法将110例肺癌患者根据检查方式的不同分为观察组(n=60,行EBUS-TBNA联合ROSE检查)和对照组(n=50,行EBUS-TBNA检查),分析两组患者的穿刺情况,比较两种检查方式的灵敏度、特异度、准确度、阴性预测值及阳性预测值。结果两组患者肿瘤穿刺直径、穿刺深度和淋巴结穿刺直径、穿刺数目及穿刺深度比较,差异均无统计学意义(P﹥0.05);观察组患者肿瘤穿刺次数、淋巴结穿刺次数均少于对照组(P﹤0.05)。观察组患者的灵敏度、特异度、准确度、阴性预测值及阳性预测值均高于对照组(P﹤0.05)。结论EBUS-TBNA联合ROSE对肺癌的诊断有着重要的价值,具有穿刺次数少、诊断准确度高的优点,值得临床推广应用。Objective To explore the diagnostic value of endobronchial ultrasound-guided transbronchial needle aspi-ration(EBUS-TBNA)combined with rapid on-site evaluation(ROSE)for lung cancer.Method A total of 110 lung can-cer patients were divided into the observation group(n=60,received EBUS-TBNA combined ROSE)and the control group(n=50,received EBUS-TBNA)according to examination methods.The puncture status was analyzed;the sensitivi-ty,specificity,accuracy,positive predictive value and negative predictive value of two methods were compared.Result There were no significant differences in tumor puncture diameter,puncture depth,lymph node puncture diameter,punc-ture number,and puncture depth between the two groups of patients(P>0.05);the tumor puncture times and lymph node puncture times in the observation group were lower than those in the control group(P<0.05).The sensitivity,specificity,accuracy,negative predictive value,and positive predictive value of the observation group were higher than those of con-trol group(P<0.05).Conclusion EBUS-TBNA combined ROSE has important value in the diagnosis of lung cancer with lower puncture numbers,higher diagnostic accuracy,it is worthy of clinical application.

关 键 词：腔内超声 经支气管镜针吸活检 现场细胞学评价 肺癌 诊断价值 

分 类 号：R734.2[医药卫生—肿瘤]