Hepatobiliar manifestations in inflammatory bowel disease: A practical approach  

作　　者：Paulina Núñez F Fabiola Castro Gabriel Mezzano Rodrigo Quera Diego Diaz Lorena Castro 

机构地区：[1]Universidad de los Andes,Inflammatory Bowel Disease Program,Digestive Disease Center,Santiago 7600976,RM,Chile [2]Inflammatory Bowel Disease Program,Hospital San Juan de Dios,Universidad de Chile,Santiago 7701230,RM,Chile [3]Universidad de los Andes,Hepatology Program,Digestive Disease Center,Santiago 7600976,RM,Chile [4]Department of Gastroenterology,Hospital del Salvador/Universidad de Chile,Santiago 7600976,RM,Chile [5]Universidad de los Andes,Santiago 770976,RM,Chile

出　　处：《World Journal of Hepatology》2022年第2期319-337,共19页世界肝病学杂志（英文版）（电子版）

摘　　要：Inflammatory bowel diseases(IBD)are associated with various hepatobiliary disorders.They can occur at any moment in the course of the disease or associated with the treatment.The prevalence of liver dysfunction can reach up to 50%in different studies.Nonalcoholic fatty liver disease is considered the most common hepatobiliary complication in IBD,while primary sclerosing cholangitis is the most specific.Management of hepatic manifestations in IBD involves a multidisciplinary approach that includes a high index of suspicion and joint management with hepatologists.The medical confrontation with abnormal liver tests must include an exhaustive study to determine if these patterns can be related to IBD,associated diseases or to the therapies used.

关 键 词：Extraintestinal manifestations Inflammatory bowel disease Sclerosing primary cholangitis Hepatic steatosis Liver toxicity 

分 类 号：R57[医药卫生—消化系统]