T1加权灌注成像在肝细胞癌诊断中的应用研究  

The Diagnostic Value of T1 Weighted Perfusion Weighted Imaging of Hepatocellular Carcinoma

作　　者：孟俊 毕俊英 刘良进 梅邹 左钢 Meng Jun;Bi Junying;Liu Liangjin;Mei Zou;Zuo Gang(Department of Radiology,Hubei Third People's Hospital Affiliated to Jianghan University,Wuhan,Hubei 430033)

机构地区：[1]江汉大学附属湖北省第三人民医院放射科,湖北武汉430033

出　　处：《现代医用影像学》2022年第1期1-4,共4页Modern Medical Imageology

摘　　要：目的:应用T1加权灌注成像技术对肝细胞癌进行扫描,分析其血流灌注特点及血流动力学变化。方法:对21例肝细胞癌患者行T1加权灌注成像检查,构建时间-信号强度曲线及灌注图,并比较肿瘤组织与正常肝实质的灌注特点,采用两样本非参数检验来分析各组灌注参数差异。结果:21例患者均成功完成了T1加权灌注检查。时间-信号强度曲线分析及灌注图显示:肿瘤感兴趣区的曲线基本均呈"速升速降"型,正常肝实质的曲线大致呈"缓升缓降"型;肿瘤区相对正常肝实质呈明显高灌注。肿瘤区的各灌注参数值均明显高于正常肝实质的灌注参数值,统计学分析两组灌注参数值均有明显统计学差异(P<0.05)。结论:T1加权灌注成像能够直观显示并量化肝细胞癌的血流灌注特点及血流动力学变化,对肝细胞癌有一定的诊断价值。Purpose:To analyze the T1 weighted perfusion characteristics and hemodynamic changes of hepatocellular carcinoma.Methods:T1 weighted perfusion imaging was performed on 21 patients with hepatocellular carcinoma,time-intensity curve and perfusion map were constructed,and the perfusion parameters of tumor tissue and normal liver parenchyma were compared.Results:Time-intensity curve and perfusion map showed:the tumor showed quick rise and quick drop;However,the normal image was supposed to be slow rise and slow drop;The tumor area is significantly higher in perfusion than normal liver parenchyma.The perfusion parameters of hepatic tumor and normal liver tissue have obvious difference(P<0.05).Conclusion:T1-weighted perfusion imaging can visually reflect and quantify the blood perfusion characteristics and hemodynamic changes of hepatocellular carcinoma,and has certain application value for hepatocellular carcinoma.

关 键 词：磁共振灌注成像 T1加权 肝细胞癌 

分 类 号：R735.7[医药卫生—肿瘤]