基因检测在精准医疗中的应用与管理  

Application and management of gene detection in precision medicine

作　　者：侯英勇 钱梦佳[2] 程韵枫[2,3] 郭玮 彭明婷 肖艳群[6] 王向东 顾建英[7] HOU Ying-yong;QIAN Meng-jia;CHENG Yun-feng;GUO Wei;PENG Ming-ting;XIAO Yan-qun;WANG Xiangdong;GU Jian-ying(Department of Pathology,Zhongshan Hospital,Fudan University,Shanghai 200032,China;Institute of Clinical Science,Zhongshan Hospital,Fudan University,Shanghai 200032,China;Department of Hematology,Zhongshan Hospital,Fudan University,Shanghai 200032,China;Department of Clinical Laboratory,Zhongshan Hospital,Fudan University,Shanghai 200032,China;National Center for Clinical Laboratories,Beijing Hospital,Beijing 100005,China;Shanghai Center for Clinical Laboratory,Shanghai 200126,China;Department of Plastic Surgery,Zhongshan Hospital,Fudan University,Shanghai 200032,China)

机构地区：[1]复旦大学附属中山医院病理科,上海200032 [2]复旦大学附属中山医院临床医学研究院,上海200032 [3]复旦大学附属中山医院血液科,上海200032 [4]复旦大学附属中山医院检验科,上海200032 [5]北京医院国家卫生健康委临床检验中心,北京100005 [6]上海市临床检验中心,上海200126 [7]复旦大学附属中山医院整形外科,上海200032

出　　处：《中国临床医学》2022年第1期7-10,共4页Chinese Journal of Clinical Medicine

基　　金：国家重点研发计划“精准医学研究”重点专项课题(2017YFC0910003)。

摘　　要：随着现代医学的发展,基因的序列信息逐渐成为临床疾病分子诊断精确的判定依据,基因检测技术也在精准医疗领域逐步推广。通过精准医学、检验医学、病理学等领域专家共同探讨基因检测在精准医疗中的应用与管理,本文明确了基因检测在精准医疗领域中的应用方法,也对基因检测每一步骤的质量控制及改进优化提出了建议,为从事精准医疗检测的实验室提供参考,进而更好地为患者服务。With the development of medicine,the information of gene sequence has gradually become the basis of accurate molecular diagnosis for many diseases,and the technology of gene detection has been gradually promoted in the precision medicine.The experts in precision medicine,laboratory medicine,pathology,and other related fields discuss the application and management of gene detection in precision medicine,and put forward proposals for the quality control,improvement and optimization of each step of gene detection methods.The target of this paper is to provide reference for all laboratories engaged in precision medicine,so as to better serve the patients.

关 键 词：基因检测 精准医疗 管理 

分 类 号：R446.9[医药卫生—诊断学]