卵巢中肾样腺癌伴交界性肿瘤一例并文献复习  

Mesonephric-Like Adenocarcinoma with Borderline Tumor in Ovary:A Case Report and Literature Review

作　　者：张世凯 刘晓慧 朱可欣 左香灵 田庚[1] ZHANG Shi-kai;LIU Xiao-hui;ZHU Ke-xin;ZUO Xiang-ling;TIAN Geng(The Second Hospital of Jilin University,Changchun 130041,China)

机构地区：[1]吉林大学第二医院,长春130041

出　　处：《国际妇产科学杂志》2022年第1期53-55,共3页Journal of International Obstetrics and Gynecology

摘　　要：卵巢中肾样腺癌(mesonephric-like adenocarcinoma)是一种表现为中肾分化的腺癌,其来源尚不确定,国内外相关报道极少。该病的诊断与治疗无特定规范,报道1例67岁女性双侧卵巢囊实性肿物,高度怀疑卵巢恶性肿瘤,给予手术治疗,术后病理诊断为双侧卵巢中肾样腺癌伴交界性浆黏液性肿瘤,该病临床表现无特异性,其病理免疫组织化学以雌激素受体(estrogen receptor,ER)和孕激素受体(progesterone receptor,PR)阴性、GATA3和甲状腺转录因子1(thyroid transcription factor-1,TTF-1)表达为特征,因缺乏该病术后特定诊疗规范,术后拟给予紫杉醇加卡铂化疗6个疗程,通过分析该病例,旨在为该病后续研究提供更多诊治参考。Mesonephric-like adenocarcinoma of the ovary is a kind of adenocarcinoma presenting as mesonephric-like differentiation.The origin of mesonephric-like adenocarcinoma is uncertain,and the related reports at home and abroad are few.There are no relevant guidelines for diagnosis and treatment of this disease.A 67-year-old woman with bilateral solid ovarian cyst and highly suspected malignant ovarian tumor was treated by operation,the postoperative pathological diagnosis was bilateral ovarian mesonephric-like adenocarcinoma with borderline serous mucinous tumor.The clinical manifestations of the disease were nonspecific.Its pathological immunohistochemistry was characterized by negative ER and PR,GATA3 and TTF-1 expression.Due to the lack of specific postoperative diagnosis and therapeutic criteria for this disease,the postoperative chemotherapy regimen of paclitaxel plus carboplatin for 6 courses was proposed.The analysis of this case was intended to provide more reference for diagnosis and treatment of this disease for subsequent studies.

关 键 词：中肾瘤 卵巢肿瘤 腺癌 黏液 诊断 治疗 预后 病例报告 中肾样腺癌 

分 类 号：R737.31[医药卫生—肿瘤]