腹腔镜在结直肠癌手术治疗中的应用  

Application of Laparoscopy in Surgical Treatment of Colorectal Cancer

作　　者：朱海丰[1] ZHU Haifeng(Department of General Surgery,Nantong Hospital of Traditional Chinese Medicine,Nantong,Jiangsu Province,226001 China)

机构地区：[1]南通市中医院普外科,江苏南通226001

出　　处：《系统医学》2021年第24期135-139,共5页Systems Medicine

摘　　要：目的分析腹腔镜在结直肠癌手术治疗中的作用。方法对南通市中医院普外科2016年1月—2020年12月收治的100例结直肠癌患者进行研究,经奇偶数法分组,将奇数者设置为对照组,偶数者设置为观察组,各为50例。予对照组患者行传统开腹式手术,观察组患者实施腹腔镜手术,对比手术情况、炎症因子、胃肠功能、恢复情况和并发症。结果观察组手术时间为(137.56±15.12)min,出血量为(54.27±9.21)mL,肠鸣音恢复时间为(2.18±0.42)d,下床活动时间为(1.21±0.16)d,引流管拔除时间为(6.21±1.54)d,与对照组比较,差异有统计学意义(t=4.977、27.048、9.096、20.830、7.871,P<0.05);观察组超敏C反应蛋白为(44.18±6.12)ng/L,肿瘤坏死因子-α为(34.56±3.72)pg/mL,白细胞介素-6为(22.18±2.24)pg/mL,低于对照组,胃泌素和胃动素水平高于对照组,差异有统计学意义(t=5.539、15.139、22.732、10.688、14.808,P<0.05);观察组出现并发症的概率为6.00%,低于对照组的22.00%,组间对比差异有统计学意义(χ^(2)=5.315,P=0.021)。结论予以结直肠癌患者腹腔镜手术,可减少炎症因子释放,对胃肠功能影响小,利于患者术后恢复,可减少手术并发症,可推广。Objective To analyze the role of laparoscopy in the surgical treatment of colorectal cancer. Methods A study was conducted on 100 patients with colorectal cancer admitted to the Department of General Surgery, Nantong Hospital of Traditional Chinese Medicine from January 2016 to December 2020. Grouped by the odd and even number method, set the odd number as the control group and the even number as the observation group, each with 50 cases.Patients in the control group underwent traditional open surgery, and patients in the observation group underwent laparoscopic surgery. Compared the operation status, inflammatory factors, gastrointestinal function, recovery status and complications. Results The operation time of the observation group was(137.56±15.12) min, the blood loss was(54.27±9.21) mL, the recovery time of bowel sounds was(2.18±0.42) d, the time to get out of bed was(1.21±0.16) d, drainage tube removal time was(6.21±1.54) d, compared with the control group, the difference was statistically significant(t=4.977, 27.048, 9.096, 20.830, 7.871, P<0.05). In the observation group, hypersensitivity C-reactive protein was(44.18±6.12) ng/L, tumor necrosis factor-α was(34.56±3.72) pg/mL, and interleukin-6 was(22.18±2.24) pg/mL, lower than the control group;and the levels of gastrin and motilin were higher than those of the control group, and the difference was statistically significant(t =5.539, 15.139, 22.732, 10.688, 14.808, P <0.05), the probability of complications in the observation group was 6.00%, which was lower than 22.00% in the control group. The difference between the groups was statistically significant(χ^(2)=5.315, P=0.021). Conclusion Laparoscopic surgery for patients with colorectal cancer can reduce the release of inflammatory factors, have a small impact on gastrointestinal function, help patients recover after surgery, and reduce surgical complications, which can be promoted.

关 键 词：腹腔镜手术 结直肠癌 炎症因子 胃肠功能 并发症 

分 类 号：R735[医药卫生—肿瘤]