COVID-19疫情爆发前后西安市第一医院儿童中低度近视进展情况对比  

Comparative Study of the Progression of Low to Moderate Myopia in Children 6−12 Years of Age in the Xi'an First Hospital before and after the Outbreak of COVID-19

作　　者：李盼 李彤 王瑾[1] 王若馨 张学辉[1] Pan Li;Tong Li;Jin Wang;Ruoxin Wang;Xuehui Zhang(Department of Ophthalmology,Xi'an First Hospital,Institute of Ophthalmology,Key Lab of Ophthalmology,Clinical Center for Ophthalmology,Xi'an 710002,China)

机构地区：[1]西安市第一医院眼科,陕西省眼科研究所,陕西省眼科学重点实验室,陕西省眼科疾病临床医学研究中心,710002

出　　处：《中华眼视光学与视觉科学杂志》2021年第12期910-917,共8页Chinese Journal Of Optometry Ophthalmology And Visual Science

摘　　要：目的:观察对比COVID-19疫情爆发前后1年西安市第一医院6~12岁儿童中低度近视的进展情况。方法:回顾性病例对照研究。收集COVID-19疫情爆发前(2018年12月至2019年1月,疫情前组)和爆发后(2019年12月至2020年1月,疫情后组)就诊于西安市第一医院眼科的6~12岁双眼近视儿童各100例(200眼),纳入具有半年和1年随访记录者。分析2组患者基线、半年随访及1年随访的眼轴长度(AL)、等效球镜度(SE)、眼轴/角膜曲率比值(AL/CR)的变化情况。数据采用独立样本t检验进行比较。结果:疫情前组100例(200眼),男42例,女58例,年龄(9.6±1.2)岁;疫情后组100例(200眼),男49例,女51例,年龄(9.2±2.4)岁。在半年随访时,疫情前组AL增长为(0.27±0.16)mm,疫情后组AL增长幅度较大,为(0.36±0.19)mm,2组差异有统计学意义(t=-6.228,P<0.001);疫情后组SE[(-0.48±0.37)Dvs.(-0.74±0.63)D,t=-2.375,P<0.001]及AL/CR(0.017±0.028vs.0.029±0.031,t=-6.052,P<0.001)的增长幅度均明显大于疫情前组。1年随访时,疫情前组AL增长为(0.46±0.31)mm,疫情后组AL增长幅度更加明显,为(0.61±0.24)mm,2组差异有统计学意义(t=1.138,P<0.001);疫情后组SE[(-0.90±0.41)Dvs.(-1.25±0.48)D,t=7.253,P<0.001]及AL/CR(0.030±0.051vs.0.046±0.036,t=5.049,P=0.032)的增长幅度均明显大于疫情前组。结论:COVID-19疫情爆发后西安市第一医院门诊就诊的6~12岁学龄段儿童近视进展速度较疫情前更快,主要表现在AL、SE和AL/CR方面。Objective:To compare the progression of low to moderate myopia in children 6-12 years of age in the Xi'an First Hospital before and after the COVID-19 epidemic.Methods:This was a retrospective cohort study.One hundred cases(200 eyes)of children 6-12 years of age with binocular myopia who were admitted to the Department of Ophthalmology in Xi'an No.1 Hospital before the outbreak of the COVID-19 epidemic(December 2018 to January 2019)and after the outbreak(December 2019 to January 2020)participated in the study.Follow-up records were recorded for 0.5 and 1 year.The mean age of the pre-epidemic group was 9.6±1.2 years,and the mean age of the post-epidemic group was 9.2±2.4 years.Changes in the ocular axis(AL),spherical equivalent(SE)and axial/corneal curvature ratio(AL/CR)at baseline,0.5 and 1 year were retrospectively analyzed in the 2 groups,and the data were compared by a paired t test.Results:At the 0.5 year follow-up,the pre-epidemic group showed less AL growth than the post-epidemic group(0.27±0.16 mm vs.0.36±0.19 mm)(t=-6.228,P<0.001),an increase in SE(-0.48±0.37 D vs.-0.74±0.63 D)(t=-2.375,P<0.001),and an increase in AL/CR ratio(0.017±0.028 vs.0.029±0.031)(t=-6.052,P<0.001).At the 1 year follow-up,the pre-epidemic group showed less AL growth than the post-epidemic group(0.46±0.31 vs.0.61±0.24)(t=1.138,P<0.001),an increase in SE(-0.90±0.41 D vs.-1.25±0.48 D)(t=7.253,P<0.001),and an increase in the AL/CR ratio(0.030±0.051 vs.0.046±0.036)(t=5.049,P=0.032).Conclusions:After the outbreak of COVID-19,the progression of myopia in 6-12 year-old school-age children in the post-epidemic is faster than in the pre-epidemic,mainly manifested in AL,SE and AL/CR。

关 键 词：COVID-19 近视 眼轴 等效球镜度 

分 类 号：R778.11[医药卫生—眼科]