植物类中药材生产过程中质量安全研究进展  

Advances in the quality and safety of Chinese herbal medicines in the producing process

作　　者：沈燕[1] 仲建锋[1] 黄亚威 郑尊涛 卢莉娜 高美静 卢飞 张志勇[1] SHEN Yan;ZHONG Jian-feng;HUANG Ya-wei;ZHENG Zun-tao;LU Li-na;GAO Mei-jing;LU Fei;ZHANG Zhi-yong(Jiangsu Key Laboratory for Food Quality and Safety-State Key Laboratory Cultivation Base,Ministry of Science and Technology/Key Laboratory for Control Technology and Standard for Agro-product Safety and Quality,Ministry of Agriculture and Rural Affairs,Institute of Food Safety and Nutrition,Jiangsu Academy of Agricultural Sciences,Nanjing 210014,China;Affiliated Hospital of Nanjing University of Traditional Chinese Medicine,Nanjing 210001,China;Institute for the Control of Agrochemicals,Ministry of Agriculture and Rural Affairs,Beijing 100125,China)

机构地区：[1]江苏省农业科学院农产品质量安全与营养研究所/省部共建国家重点实验室培育基地——江苏省食品质量安全重点实验室/农业农村部农产品质量安全控制技术与标准重点实验室,江苏南京210014 [2]南京中医药大学附属医院,江苏南京210001 [3]农业农村部农药检定所,北京100125

出　　处：《江苏农业学报》2022年第1期268-277,共10页Jiangsu Journal of Agricultural Sciences

基　　金：科技部重点研发专项项目(2017YFC1700800);国家自然科学基金项目(31772198);国家药典委员会药品标准制修订研究课题(2020Z07、2021Z10);江苏省林业局风险监测项目[LYKJ(2020)13]。

摘　　要：中药在保护人类健康方面发挥着关键功能,中药材作为中药生产中不可或缺的环节,其质量安全备受关注。影响中药材质量安全的因素根据其源头不同包括农药残留、重金属污染和真菌毒素残留等。本文综述了这3种影响中药材质量安全因素及其限量标准与检测方法等方面的新近研究进展,全面分析了这3种质量安全因子国内外限量标准及检测方法的差异,并提出了合理的改进提升措施。以期为有效防控中药材的质量安全风险提供指导,为中药材质量安全控制体系的建立与完善提供有益的参考。Chinese herbal medicines(CHMs)play important roles in protecting human health.As an important part of traditional Chinese medicine,its quality and safety have attracted much attention.The factors affecting the quality and safety of CHMs mainly include pesticide residues,heavy metal pollution and mycotoxin residues according to their sources.The paper reviewed new research progress of these three factors affecting the quality and safety,limit standards and detection methods in CHMs.Moreover,the differences in limit standards and detection methods of these factors at home and abroad were comprehensively analyzed,and reasonable improvement measures were proposed.These results can provide guidance for the effective prevention and control of quality and safety risks of CHMs,and provide a useful reference for the establishment and improvement of the quality and safety control system of CHMs.

关 键 词：中药材 农药登记 农药残留 重金属污染 真菌毒素 限量标准 

分 类 号：R282.4[医药卫生—中药学]