口腔颌面部鳞癌手术治疗的临床疗效研究  

Clinical Value of Surgical Treatment for Oral and Maxillofacial Squamous Cell Carcinoma

作　　者：任婷婷 卢泰青 滕薇 郭华[1] REN Tingting;LU Taiqing;TENG Wei(The First Affiliated Hospital of Zhengzhou University,Zhengzhou,450000)

机构地区：[1]郑州大学第一附属医院,450000

出　　处：《实用癌症杂志》2022年第2期237-239,共3页The Practical Journal of Cancer

基　　金：河南省医学科技攻关计划(编号:20170082)。

摘　　要：目的探讨手术治疗口腔颌面部鳞癌的临床疗效。方法选取口腔颌面部鳞癌患者62例,按随机数字表法分为观察组(n=31)与对照组(n=31),对照组采用下颌骨节段切除术治疗,观察组采用下颌骨边缘性切除术治疗。对比两组围术期情况、颜面部评分、预后情况、生活质量核心量表(QLQ-C30)评分。结果观察组术中出血量较对照组少,手术时间、住院时间均较对照组短(P<0.05);观察组整体自视、社会评价、生活适应和综合评分较对照组高(P<0.05);观察组无瘤生存率为76.67%(23/30)、转移率为6.67%(2/30)、复发率为20.00%(6/30),与对照组[73.33%(22/30)、6.67%(2/30)、23.33%(7/30)]相比无显著差异(P>0.05);术后2年,观察组QLQ-C30评分较对照组低(P<0.05)。结论口腔颌面部鳞癌采用手术治疗可缩短手术时间,减少术中出血量,加快患者康复进程,并可改善预后,减轻对颜面部影响,提高生活质量。Objective To explore the clinical value of surgical treatment of oral and maxillofacial squamous cell carcinoma.Methods 62 patients with oral and maxillofacial squamous cell carcinoma were randomly divided into the observation group(n=31) and the control group(n=31).The control group was treated with mandibular segmental resection, and the observation group was treated with mandibular marginal resection.The perioperative situation, facial score, prognosis and quality of life core scale(QLQ-C30) scores were compared between the 2 groups.Results The amount of intraoperative bleeding in the observation group was less than that in the control group, and the operation time and hospital stay were shorter than those in the control group(P<0.05);The overall self-esteem, social evaluation, life adaptation and comprehensive scores of the observation group were higher than those of the control group(P<0.05);The tumor free survival rate, metastasis rate and recurrence rate of the observation group were 76.67%(23/30),6.67%(2/30) and 20.00%(6/30).There was no significant difference between the observation group and the control group [73.33%(22/30),6.67%(2/30) and 23.33%(7/30)](P>0.05);Two years after operation, the QLQ-C30 score in the observation group was lower than that in the control group(P<0.05).Conclusion Surgical treatment of oral and maxillofacial squamous cell carcinoma can shorten the operation time, reduce the amount of intraoperative bleeding, accelerate the rehabilitation process, improve the prognosis, reduce the impact on the face and improve the quality of life.

关 键 词：口腔颌面部鳞癌 手术治疗 围术期情况 复发情况 颜面部评分 

分 类 号：R739.8[医药卫生—肿瘤]