3.0T磁共振弥散加权成像技术对食管癌精准放化疗的效果预测和价值评估  

Prediction and evaluation of 3.0T MR diffusion weighted imaging for the curative effects of esophageal cancer

作　　者：李丁丁[1] 郑香[1] 史利红[1] 付敬华 张文艳 LI Dingding;ZHENG Xiang;SHI Lihong(Department of Magnetic Resonance,Tangshan People’s Hospital,Hebei,Tangshan 063001,China)

机构地区：[1]河北省唐山市人民医院磁共振室,063001

出　　处：《河北医药》2022年第2期239-241,245,共4页Hebei Medical Journal

基　　金：河北省医学科学研究重点课题计划(编号:20201533)。

摘　　要：目的探究对行精准放化疗食管癌患者施行3.0T磁共振弥散加权成像技术的预测疗效价值。方法随机抽取2018年1月至2019年8月72例食管癌患者(均施行精准放化疗)为观察对象,对其均实施CT扫描(对照组)、3.0T磁共振弥散加权成像技术(观察组)扫描,以病理标本收缩比回推至实际病变长度为参照,比较两种检查方法食管癌病变测量长度,并随访半年,比较表现扩散系数(ADC)值。结果观察组中,b=600 s/mm^(2)测量的病变长度和实际病变长度最接近,二者差异无统计学意义(P>0.05),但对照组和观察组b=400、800 s/mm^(2)测量的病变长度均和实际病变长度差异有统计学意义(P<0.05);放化疗后不同b值情况下ADC值均较放化疗前更高(P<0.05)。缓解组放化疗后ADC值较未缓解组更高(P<0.05)。未复发组放化疗后ADC值较复发组更高(P<0.05)。结论对行精准放化疗食管癌患者施行3.0T磁共振弥散加权成像技术有助于评估其放化疗效果及预后,对医师制定后续治疗方案具有良好指导意义。Objective To investigate the prediction and evaluation value of 3.0T magnetic resonance diffusion weighted imaging(DWI)for the curative effect in patients with esophageal cancer undergoing precise radiotherapy and chemotherapy.Methods A total of 72 patients with esophageal cancer who were treated by precise radiotherapy and chemotherapy in our hospital from January 2018 to August 2019 were enrolled in the study,who were randomly divided into control group and observation group.The patients in control group underwent CT scanning,however,the patients in observation group underwent 3.0T magnetic resonance diffusion-weighted imaging examination.The contraction ratio of pathological specimens back to the actual lesion length was taken as reference.The length of esophageal cancer lesions measured by the two methods was compared and followed up 6 months to compare the ADC value.Results In observation group,the lesion length measured by b=600s/mm^(2) was the closest to the actual lesion length,there was no significant difference between them(P>0.05),however,there was significant difference in the length of lesions measured by s/mm^(2) and the actual length of lesions between the two groups(P<0.05).After radiotherapy and chemotherapy,the ADC values at different b values were increased(P<0.05),which in remission group were significantly higher than those in non remission group(P<0.05),moreover,which in non recurrence group were significantly higher than those in recurrence group(P<0.05).Conclusion The application of 3.0T magnetic resonance diffusion weighted imaging for the patients with esophageal cancer undergoing precise radiotherapy and chemotherapy is helpful to evaluate the curative effects and prognosis of patients,which has good guiding significance for doctors to formulate the latter treatment plan.

关 键 词：精准放化疗 食管癌 3.0T磁共振弥散加权成像技术 预测 疗效 

分 类 号：R735.1[医药卫生—肿瘤]