芪参通脉汤治疗缺血性脑卒中恢复期患者的效果  

Effect of Qishen Tongmai Decoction on Convalescent Patients with Ischemic Stroke

作　　者：白会丽 李晓 BAI Huili;LI Xiao(Department of Traditional Chinese Medicine,Xinzheng Second People’s Hospital,Zhengzhou 451100,China)

机构地区：[1]新郑市第二人民医院中医科,河南郑州451100

出　　处：《河南医学研究》2022年第4期704-707,共4页Henan Medical Research

摘　　要：目的探讨芪参通脉汤治疗缺血性脑卒中恢复期患者的效果。方法选取2019年1月至2021年1月新郑市第二人民医院中医科收治的93例缺血性脑卒中患者,根据治疗方法分为观察组(43例)与对照组(50例)。对照组口服阿司匹林肠溶片治疗,观察组接受芪参通脉汤治疗,连续治疗4周。比较两组疗效,比较治疗前后神经功能的缺损程度与日常能力,比较治疗前后两组血脂、超敏C反应蛋白(hs-CRP)、血液流变学指标的水平以及不良反应的发生率。结果治疗后观察组总有效率高于对照组(P>0.05)。治疗后,两组患者日常生活能力评分均较治疗前升高,且观察组高于对照组,两组神经功能缺损程度评分较治疗前降低,且观察组低于对照组(P<0.05)。治疗后两组甘油三酯、低密度脂蛋白胆固醇水平较治疗前降低,且观察组低于对照组,两组高密度脂蛋白胆固醇水平较治疗前升高,且观察组高于对照组(P<0.05)。治疗后两组患者hs-CRP、全血高切黏度、全血低切黏度、血浆黏度较治疗前降低,且观察组低于对照组(P<0.05)。观察组不良反应发生率低于对照组(P<0.05)。结论芪参通脉汤应用于缺血性脑卒中恢复期可改善患者的神经功能缺损与日常生活能力,改善患者血脂、hs-CRP、血液流变学相关指标,且不良反应发生率低,具有重要的参考价值。Objective To investigate the effect of Qishen Tongmai decoction on convalescent patients with ischemic stroke.Methods A total of 93 patients in Department of Traditional Chinese Medicine of Xinzheng Second People’s Hospital from January 2019 to January 2021 were collected,and they were divided into observation group(43 cases)and control group(50 cases)according to treatment methods.The control group received aspirin enteric-coated tablets,while the observation group received Qishen Tongmai Decoction,continuous treatment for 4 weeks.The curative effects of the two groups were compared,the degree of neurological deficit and daily ability before and after treatment were compared,and the levels of blood lipid,high-sensitivity C-reactive protein(hs-CRP),hemorheological indexes before and after treatment and the incidence of adverse reactions were compared between the two groups.Results After treatment,the total effective rate of observation group was higher than that of control group(P>0.05).After treatment,the scores of activities of daily living of two groups were higher than those before treatment,and the score of observation group was higher than that of control group,and the scores of neurological deficit of two groups were lower than those before treatment,and the score of observation group was lower than that of control group(P<0.05).After treatment,the levels of triglyceride and low-density lipoprotein cholesterol of two groups were lower than those before treatment,and the level of observation group was lower than that of control group,and the levels of high-density lipoprotein cholesterol of two groups were higher than those before treatment,and the level of observation group was higher than that of control group(P<0.05).After treatment,hs-CRP,whole blood high shear viscosity,whole blood low shear viscosity and plasma viscosity of two groups were lower than those before treatment,and the observation group was lower than that of control group(P<0.05).The incidence of adverse reactions of observation group w

关 键 词：芪参通脉汤 缺血性脑卒中 神经功能的缺损程度 日常能力 疗效 

分 类 号：R743.31[医药卫生—神经病学与精神病学]