脑梗死患者梗死面积的影响因素分析  

Influencing Factors of Infarct Size in Patients with Cerebral Infarction

作　　者：杨丽[1] 谭红艳[1] 王忠红[1] YANG Li;TAN Hongyan;W ANG Zhonghong(Department of Radiology,East Hospital of Jiamusi Central Hospital,Jiamusi 154002,China)

机构地区：[1]佳木斯中心医院东院区放射影像科,黑龙江佳木斯154002

出　　处：《河南医学研究》2022年第3期482-485,共4页Henan Medical Research

摘　　要：目的探讨脑梗死患者梗死面积的影响因素。方法选取2019年7月至2021年3月佳木斯中心医院东院区收治的825例脑梗死患者,根据Adama分类标准将患者分为大面积梗死组(318例)和小面积梗死组(507例),另选取同期健康体检者300例作为对照组。比较脑梗死组和对照组血脂、凝血、血压、吸烟、饮酒情况,比较大面积梗死组和小面积梗死组血脂、凝血、血压等相关指标,采用Pearson相关性分析梗死面积与各项指标的相关性,采用logistic回归分析脑梗死患者梗死面积的影响因素。结果脑梗死组总胆固醇、甘油三酯、低密度脂蛋白胆固醇(LDL-C)、D-二聚体(D-D)、纤维蛋白原(Fib)、舒张压及收缩压水平高于对照组(P<0.05),凝血酶原时间、活化部分凝血活酶时间(APTT)短于对照组(P<0.05)。大面积梗死组总胆固醇、甘油三酯、LDL-C、D-D、Fib、舒张压、收缩压水平高于小面积梗死组(P<0.05),凝血酶原时间、APTT短于小面积梗死组(P<0.05)。脑梗死面积与总胆固醇、甘油三酯、LDL-C、D-D、Fib、舒张压、收缩压呈正相关(P<0.05),与凝血酶原时间、APTT呈负相关(P<0.05)。logistic回归分析结果显示,高总胆固醇、高甘油三酯、高D-D、高Fib、高收缩压均是影响脑梗死患者梗死面积的危险因素(P<0.05)。结论脑梗死患者的梗死面积与血脂、凝血、血压指标相关,其水平异常可能是大面积脑梗死的重要危险因素。Objective To investigate the influencing factors of infarct size in patients with cerebral infarction patients.Methods A total of 825 patients with cerebral infarction treated in East Hospital of Jiamusi Central Hospital from July 2019 to March 2021 were selected.According to Adama classification criteria,the patients were divided into large-area infaretion group(318 cases)and small-area infaretion group(507 cases).A total of 300 healthy people during the same period were selected a control group.The blood lipid,blood coagulation,blood pressure,smok ing and drinking between cerebral infarction group and control group were compared,and the blood lipid,blood coagulation,blood pressure and other related indicators between large-area infarction group and small-area infarction group were compared.Pearson correlation was used to analyze the correlation between the infarct area and various indicators.Logistic regression was used to analyze the influencing factors of infarct size in patients with cerebral infarction.Results The levels of total cholesterol,triglyceride,low-density lipoprotein cholesterol(LDL-C),D-dimer(D-D),fibrinogen(Fib),diastolic blood pressure and systolic blood pressure in cerebral infarction group were higher than those in control group(P<0.05),and prothrombin time and activated partial prothrombin time were shorter than those in control group(P<0.05).The levels of total cholesterol,triglyceride,LDL-C,D-D,Fib,diastolie blood pressure and systolic blood pressure in large-area infarction group were higher than those in small-area infaretion group(P<0.05),and the prothrombin time and activated partial prothrombin time(APTT)in large-area infarction group were shorter than those in small-area infarction group(P<0.05).The area of cerebral infarction was positively correlated with total cholesterol,triglyceride,LDL-C,D-D,Fib,diastolic blood pressure and systolic blood pressure(P<0.05),negatively correlated with prothrombin time and APTT(P<0.05).Logistic regression analysis showed that high total cholestero

关 键 词：脑梗死 血脂指标 凝血指标 

分 类 号：R743.33[医药卫生—神经病学与精神病学]