IgG4相关消化道损害的新认识  

New insights into IgG4-related gastrointestinal damage

作　　者：何雨芩 陈东风 HE Yuqin;CHEN Dongfeng(Department of Gastroenterology,Army Specialty Medical Center(Daping Hospital),Army Medical University,Chongqing 400042,China)

机构地区：[1]陆军军医大学陆军特色医学中心(大坪医院)消化内科,重庆400042

出　　处：《西南医科大学学报》2022年第1期13-16,25,共5页Journal of Southwest Medical University

基　　金：国家自然科学基金青年基金(81700466);重庆市自然科学基金面上项目(cstc2019jcyj-msxm0384);重庆市科卫联合医学科研项目(2020MSXM073)。

摘　　要：IgG4相关性疾病是一类自身免疫功能紊乱引起,以慢性纤维化炎症为特征的多系统性疾病。IgG4-RD很可能是一种被低估的罕见病,特别是IgG4相关消化道疾病的发病情况研究较少,国内目前没有针对IgG4相关消化道疾病的专家共识或指南。本文将从IgG4相关性疾病的概况、IgG4相关消化道疾病的临床特征、IgG4相关疾病的诊断与治疗进展进行阐述,以期提高临床医生对该病的临床认识。IgG4-related disease is a multisystem disease caused by autoimmune dysfunction and characterized by chronic in⁃flammation and fibrosis.IgG4-related disease is likely to be an underestimated rare disease,and the incidence of IgG4-related gastro⁃intestinal disease in particular is poorly studied.Until now,there is no relevant expert consensus or guidance for IgG4-related gastroin⁃testinal disease in China.This article gives an overview of IgG4-related disease and reviews clinical features of IgG4-related gastroin⁃testinal disease and advances in the diagnosis and treatment of IgG4-related disease,in order to improve the understanding of the dis⁃ease in clinicians.

关 键 词：IGG4相关性疾病 免疫功能紊乱 消化道损害 

分 类 号：R57[医药卫生—消化系统]