膀胱原发间叶性软骨肉瘤1例报告并文献复习  

A case report of primary mesenchymal chondrosarcoma of the bladder and review of the literature

作　　者：谢强[1] 郭琦 Xie Qiang;Guo Qi(Department of Urology,Tianshui First People′s Hospital,Tianshui Gansu 741000,China)

机构地区：[1]天水市第一人民医院泌尿外科,甘肃天水741000

出　　处：《保健医学研究与实践》2022年第2期74-77,共4页Health Medicine Research and Practice

摘　　要：目的探讨膀胱原发间叶性软骨肉瘤的病因、病理、临床表现、诊断、鉴别诊断及治疗。方法回顾性复习1例膀胱原发间叶性软骨肉瘤病例的诊治经过,复习相关文献,总结膀胱原发间叶性软骨肉瘤的临床特征。结果本文报道1例患者为女性,69岁,以反复尿频尿急尿痛3个月为主要临床表现。其12年前曾患宫颈癌,行放射治疗并临床治愈。超声及X线片检查均提示为膀胱结石,膀胱镜检查见附着于膀胱左侧壁的结石样肿物,经CT平扫+增强检查后诊断为膀胱肿瘤,行经尿道膀胱肿瘤等离子电切术,术后经本院病理、外院病理检查后,明确诊断为膀胱原发间叶性软骨肉瘤。结论膀胱间叶性软骨肉瘤是极罕见的膀胱恶性肿瘤,其病因目前不清楚,常以肉眼血尿为首发症状,也有以下尿路刺激症状、排尿困难、上尿路梗阻积水为首发症状者,影像学检查有一定特征,病变内可出现点状或不规则的钙化影,明确诊断需依赖病理学检查。该病恶性程度高,易复发、转移早、预后差,一旦确诊应行根治性膀胱切除术治疗。Objective To investigate the etiology,pathology,clinical manifestations,diagnosis,differential diagnosis and treatment of primary mesenchymal chondrosarcoma of the bladder.Methods Retrospectively reviewing the diagnosis and treatment of a case of primary mesenchymal chondrosarcoma of the bladder,reviewing the relevant literature,and summarizing the clinical features of primary mesenchymal chondrosarcoma of the bladder.Results In this paper,we report a case of a female,69 years old,with recurrent urinary frequency and urgency and painful urination for 3 months as the main clinical manifestation.She had cervical cancer 12 years ago,which was treated with radiation therapy and clinically cured.Ultrasound and radiographs suggested bladder stones,and cystoscopy revealed a stone-like mass attached to the left wall of the bladder.Conclusion Mesenchymal chondrosarcoma of the bladder is an extremely rare malignant tumor of the bladder,the etiology of which is not clear at present.The most common initial symptom for this disease is sarcoid hematuria,but there are also cases with urinary tract irritation,difficulty in urination,and fluid accumulation and obstruction in the upper urinary tract as the initial symptom.The disease is highly malignant and prone to recurrence,early metastasis and poor prognosis;it should be treated with radical cystectomy once diagnosed.

关 键 词：膀胱肿瘤 间叶性软骨肉瘤 诊断 治疗 

分 类 号：R734.2[医药卫生—肿瘤]