抗坏血酸在多壁碳纳米管修饰玻碳电极上的电化学行为及其与DNA的相互作用  

Electrochemical Behavior of Ascorbic Acid on Multi-walled Nanotubes Modified Glassy Carbon Electrode and the Intercation Asarbic Acid with DNA

作　　者：尚永辉[1] 李子媛 刘鑫雨 张恒 刘冬阳 SHANG Yonghui;LI Ziyuan;LIU Xinyu;ZHANG Heng;LIU Dongyang(School of Chemistry&Chemical Engineering,Xianyang Normal University,Xianyang 712000,Shaanxi,China)

机构地区：[1]咸阳师范学院化学与化工学院,陕西咸阳712000

出　　处：《咸阳师范学院学报》2021年第6期37-40,71,共5页Journal of Xianyang Normal University

基　　金：国家自然科学基金项目(21475113);咸阳师范学院“拔尖人才”项目(XSYBJ201902);咸阳师范学院科研基金项目(XSYK19046);咸阳师范学院大学生创新创业训练计划项目(DC2020035);咸阳师范学院第七批入驻大学生创新创业基地团队项目(XSYC202113);陕西省大学生创新创业训练计划项目(S202010722035)。

摘　　要：应用循环伏安法和差分脉冲伏安法探索了抗坏血酸在多壁碳纳米管修饰玻碳电极上的电化学行为,实验发现在pH=5.6的磷酸氢二钠-柠檬酸底液中抗坏血酸能产生良好的电化学信号,氧化峰、还原峰峰电位分别为0.091 0、0.055 2 V,在修饰电极上的氧化峰电流信号是裸电极上的3.2倍,表明多壁碳纳米管对抗坏血酸具有明显的催化作用。基于此建立了测定抗坏血酸的新方法,研究了抗坏血酸与DNA的相互作用。Application of cyclic voltammetry and differential pulse voltammetry explores the ascorbic acid in multi-walled carbon nanotubes modified glassy carbon electrode electrochemical behavior, it was found that in the pH=5.6 disodium hydrogen phosphate-ascorbic citric acid liquid at the bottom. Acid can produce with good cyclic voltammetric curves, oxidation, reduction of fengfeng potential 0.0910 V, 0.0552 V, the oxidation peak current of the modified electrode is 3.2 times that on the bare electrode, multi-walled carbon nanotubes against bad blood acid has obvious catalysis. Based on this, a new method for the determination of ascorbic acid was established, with the interaction between ascorbic acid and DNA studied.

关 键 词：抗坏血酸 DNA 多壁碳纳米管修饰玻碳电极 电化学行为 

分 类 号：R917[医药卫生—药物分析学]