基于变形链球菌感染水平以及年龄性别等因素构架预测低龄儿童龋齿回归模型  

Regression model for predicting dental caries in children based on the level of Streptococcus mutans infection,age and gender

作　　者：彭源 孙琦 李路平 PENG Yuan;SUN Qi;LI Lu-ping(Department of Stomatology,Zhengzhou Stomatology Hospital,Zhengzhou 450000,Henan,China)

机构地区：[1]郑州市口腔医院儿童口腔科,河南郑州450000

出　　处：《广东医学》2022年第1期65-69,共5页Guangdong Medical Journal

基　　金：河南省医学科技攻关计划项目(2018032118)。

摘　　要：目的探究基于变形链球菌感染水平以及年龄性别等因素构架预测低龄儿童龋齿回归模型。方法选择进行龋齿检查的128例低龄儿童为研究对象,行口腔健康检查后,根据低龄儿童是否存在龋齿将其分为龋齿组65例和非龋齿组63例。应用单因素分析和多因素分析探究低龄儿童发生龋齿的相关因素和独立危险因素。应用Spearman相关性分析探究患者年龄、性别、变性链球菌感染水平与龋齿发生的相关性。以ROC分析曲线评价上述因素水平对低龄儿童龋齿发生的评估价值。结果(1)经单因素分析结果表明年龄、性别、变形链球菌感染、牙龈指数、偏好甜食均是低龄儿童是否发生龋病的影响因素(P<0.05);(2)logistic多因素回归显示,变形链球菌感染水平、年龄、性别、牙龈指数>0、偏好甜食是影响低龄儿童龋齿发生的独立危险因素(P<0.05);(3)Spearman相关分析显示:低龄儿童龋齿发生率与变形链球菌感染水平、年龄、牙龈指数、每天甜食使用次数呈正相关(P<0.05);(4)ROC曲线研究结果表明多项研究指标联合应用对低龄儿童龋齿的发生进行诊断的效能较高,其敏感度(0.891)、特异度(0.882)以及曲线下面积(0.890)均高于任何单一指标。结论低龄儿童龋齿的发生与年龄、性别、变形链球菌感染、牙龈指数、偏好甜食密切相关,针对上述指标的监测可一定程度上预测低龄儿童龋齿的发生。Objective To evaluate a regression model for predicting dental caries in children based on the level of Streptococcus mutans infection,age and sex.Methods From June 2018 to June 2020,128 children who came to the hospital for examination were enrolled and assigned into caries group(n=65)and non-caries group(n=63).Single factor analysis and multiple factor analysis were applied to investigate the correlated factors of dental caries and independent risk factors in children Spearman correlation analysis was applied to evaluate the correlations between age,gender,or streptococcus infection and dental caries,and ROC was used to evaluate diagnostic significance of these factors.Results The results of univariate analysis showed that age,sex,streptococcus mutans infection,gingival index and preference for sweets were influencing factors of caries in children(P<0.05).Logistic multivariate regression showed that Streptococcus mutans infection level,age,gender,gingival index>0,preference for sweets were independent risk factors for dental caries in children(P<0.05).Spearman correlation analysis showed that the incidence of dental caries in young children was positively correlated with the level of Streptococcus mutans infection,age,gingival index,and the number of daily sweets used(P<0.05).The results of ROC study show that the combined application of multiple indicators was more effective in the diagnosis of the occurrence of dental caries in children;with the sensitivity of 0.891,the specificity of 0.882 and the area under the curve of 0.890,which were all higher than any single indicator.Conclusion The dental caries in children is closely correlated to age,sex,streptococcus mutans infection,gingival index and preference for sweet food.The monitoring of the above indexes can predict the incidence of dental caries in young children to a certain extent.

关 键 词：变形链球菌 龋齿 儿童 回归模型 

分 类 号：R788.1[医药卫生—口腔医学] R378[医药卫生—临床医学]