颅内动脉瘤介入栓塞术后复发患者创伤后应激障碍状况及影响因素分析  

Analysis of post-traumatic stress disorder status in patients with recurrent intracranial aneurysms after interventional embolization and its influencing factors

作　　者：热依拉·艾力 许姗姗[1] 王敏囡 郭璇[3] 买买提力·艾沙[4] Reyila·Aili;Xu Shanshan;Wang Minnan;Guo Xuan;Maimaitili·Aisha(Emergency Trauma Center,the First Hospital Affiliated to Xinjiang Medical University,Urumqi 830054,China;Department of Child Health,Health Management Hospital,the First Hospital Affiliated to Xinjiang Medical University,Urumqi 830054,China;Department of Nursing,the First Hospital Affiliated to Xinjiang Medical University,Urumqi 830054,China;Department of Neurosurgery,the First Hospital Affiliated to Xinjiang Medical University,Urumqi 830054,China)

机构地区：[1]新疆医科大学第一附属医院急救创伤中心,乌鲁木齐830054 [2]新疆医科大学第一附属医院健康管理院儿童保健科,乌鲁木齐830054 [3]新疆医科大学第一附属医院护理部,乌鲁木齐830054 [4]新疆医科大学第一附属医院神经外科,乌鲁木齐830054

出　　处：《神经疾病与精神卫生》2022年第2期100-105,共6页Journal of Neuroscience and Mental Health

基　　金：国家卫生健康委“中国脑卒中高危人群干预适宜技术研究及推广项目”(GN-2020R0001)。

摘　　要：目的调查颅内动脉瘤介入栓塞术后复发患者创伤后应激障碍(PTSD)状况,并探讨其影响因素。方法选取2019年1月至2021年1月于新疆医科大学第一附属医院接受治疗的290例颅内动脉瘤介入栓塞术后复发患者作为研究对象,采用创伤性应激障碍自评量表(PTSD-SS)评价PTSD状况,统计PTSD-SS总分及PTSD发生率。分别采用匹兹堡睡眠质量指数(PSQI)和生活质量综合评定量表(GQOLI-74)评价患者睡眠质量和生活质量。采用Pearson相关分析PTSD-SS总分与PSQI总分、GQOLI-74总分相关性。采用二元Logistic回归分析颅内动脉瘤介入栓塞术后复发患者发生PTSD的影响因素。结果颅内动脉瘤介入栓塞术后复发患者PTSD-SS总分为44.00(41.00,49.00)分,PTSD发生率为24.8%(72/290)。PTSD-SS总分与PSQI总分呈正相关(r=0.418,P<0.05),与GQOLI-74总分呈负相关(r=-0.466,P<0.05)。二元Logistic回归分析显示,年龄<60岁、无配偶、家庭月收入≤1万元、合并焦虑、低水平社会支持和动脉瘤大复发均是颅内动脉瘤介入栓塞术后复发患者发生PTSD的危险因素(OR=17.346、2.447、3.740、4.981、2.554、5.004;P<0.05)。结论颅内动脉瘤介入栓塞术后复发患者PSTD发生率高,且PTSD与睡眠质量和生活质量相关。年龄<60岁、无配偶、家庭月收入≤1万元、合并焦虑、低水平社会支持和动脉瘤大复发均是颅内动脉瘤介入栓塞术后复发患者发生PTSD的危险因素。Objective To investigate the status of post-traumatic stress disorder(PTSD)in patients with recurrent intracranial aneurysms after interventional embolization and to discuss its influencing factors.Methods A total of 290 patients with recurrent intracranial aneurysms after interventional embolization who received therapy in the First Hospital Affiliated to Xinjiang Medical University from January 2019 to January 2021 were selected as the research objects.The PTSD status was evaluated by Post-traumatic Stress Disorder Self-rating Scale(PTSD-SS),and the total score and incidence of PTSD were counted.Pittsburgh Sleep Quality Index(PSQI)and General Quality of Life-74(GQOLI-74)were used to evaluate the sleep quality and quality of life.Pearson correlation analysis was used to analyze the correlation between the total PTSD-SS score,the total PSQI score,and the total GQOLI-74 score.Binary logistic regression was used to analyze the influencing factors of PTSD in patients with recurrent intracranial aneurysms after interventional embolization.Results The total PTSD score of patients with recurrent intracranial aneurysms after interventional embolization was 44.00(41.00,49.00)points,and the incidence of PTSD was 24.8%(72/290).The total PTSD-SS score was positively correlated with the total PSQI score(r=0.418)and negatively correlated with the total GQOLI-74 score(r=-0.466).The differences were both statistically significant(both P<0.05).Binary logistic regression analysis showed that age less than 60 years old,no spouse,family monthly income less than or equal to 10000 yuan,combined anxiety,low level of social support and large aneurysm recurrence were the risk factors for PTSD in patients with recurrent intracranial aneurysms after interventional embolization(OR=17.346,2.447,3.740,4.981,2.554,5.004;all P<0.05).Conclusions Patients with recurrent intracranial aneurysms after interventional embolization have a high incidence of PTSD,which is related to sleep quality and quality of life.Age less than 60 years old,no spouse,

关 键 词：颅内动脉瘤 介入栓塞术 复发 创伤后应激障碍 影响因素 

分 类 号：R749.5[医药卫生—神经病学与精神病学]