不同方法治疗非痴呆型血管性认知功能障碍的疗效观察  

Clinical Effect Observation of Vascular Cognitive Impairmentno Dementia by Different Treatment Methods

作　　者：吕倩倩 Qianqian Lv(Department of NICU,Sanmenxia Central Hospital,Sanmenxia,Henan 472000,China)

机构地区：[1]河南省三门峡市中心医院神经内科重症监护室,河南三门峡472000

出　　处：《西藏医药》2022年第1期18-20,共3页Tibetan Medicine

摘　　要：目的探讨不同方法治疗非痴呆型血管性认知功能障碍(VCIND)的疗效。方法选取我院2018年1月~2020年5月收治的VCIND患者73例,按随机数字表法分为A组(n=36)、B组(n=37),患者均采用电刺激小脑顶核治疗。在此基础上A组联合尼莫地平,B组联合奥拉西坦治疗。治疗4周后,对比两组的临床疗效及简易精神状态检查量表(Mini-mental State Examination, MMSE)评分。结果经颅多普勒超声显示,平均脑血流速度的改善A组显著优于B组(包括大脑中动脉、大脑前动脉、大脑后动脉)。A组MMSE评分显著高于B组(P<0.05)。结论患者认知功能的好转与脑血流的改善有关。Objective: To observe of clinical effect of vascular cognitive impairment-no dementia (VCIND) by different treatment methods.Methods: Totally, 73 patients with VCIND were admitted and treated in Sanmenxia Central Hospital from January 2018 to May 2020. They were divided into A group (n=36) and B group (n=37). Patients in A group were treated by fastigial nucleus stimulation combined with nimodipine, while patients in B group were treated by fastigial nucleus stimulation combined with oxiracetam. After four weeks treatment,the clinical treatment results and the scores of MMSE were compared between the two groups.Results: TCD showed that cerebral blood flow velocity (including MCA, ACA and PCA) in the A group was significant better than that in the B group. The scores of MMSE in the A group was significant higher than that in the B group (P< 0.05).Conclusions: The cognitive function recovery is associated with cerebral blood flow improvement.

关 键 词：非痴呆型血管认知功能障碍 尼莫地平 电刺激小脑顶核 

分 类 号：R749.13[医药卫生—神经病学与精神病学]