红外定位系统在胸腹部肿瘤放射治疗中的应用  

Application of optical positioning system in radiotherapy of thoracic and abdominal tumors

作　　者：孙超 葛彬彬[1] 蔡晶[1] 金建华[1] 葛云[2] 储开岳[1] SUN Chao;GE Binbin;CAI Jing;JIN Jianhua;GE Yun;CHU Kaiyue(Department of Radiotherapy,Nantong Tumor Hospital(Tumor Hospital Affiliated to Nantong University),Jiangsu Nantong 226361,China;School of Electronic Science and Engineering,Nanjing University,Jiangsu Nanjing 210093,China)

机构地区：[1]南通市肿瘤医院(南通大学附属肿瘤医院)放疗科,江苏南通226361 [2]南京大学电子科学与工程学院,江苏南京210093

出　　处：《现代肿瘤医学》2022年第6期1068-1072,共5页Journal of Modern Oncology

基　　金：江苏省重点研发计划(编号:BE2017679)。

摘　　要：目的:研究红外定位系统(optical positioning system,OPS)在胸腹部肿瘤放射治疗中对摆位误差的指导意义。方法:选择30例胸腹部肿瘤患者,均采用改进型仰卧位固定技术固定,所有患者均辅以OPS标记。患者治疗时按常规方法对照激光线摆位,行锥形束CT(cone beam computed tomography,CBCT)扫描后移床治疗,记录移床后的CBCT误差值(对照组)以及OPS读数(观察组),包括X(左右方向)、Y(头脚方向)、Z(腹背方向)三个方向的线性误差,并分析比较两种误差结果。结果:以CBCT为标准,常规对激光线摆位的线性误差X、Y、Z三个方向分别为(1.95±1.16)mm、(3.87±1.67)mm、(1.71±1.03)mm;对应的OPS显示误差X、Y、Z三个方向分别为(0.63±0.56)mm、(0.31±0.49)mm、(0.32±0.22)mm。三个方向上OPS误差均小于传统摆位误差,差异有统计学意义(P<0.05)。结论:OPS辅助摆位技术与常规对激光线摆位相比,在放疗中可明显减小胸腹部肿瘤患者的摆位误差,提高治疗时的摆位精度,给临床胸腹部肿瘤患者放疗的摆位提供参考。Objective:To study the guiding significance of optical positioning system(OPS)in radiotherapy of thoracic and abdominal tumors for setting error.Methods:30 patients with thoracic and abdominal tumors were fixed with improved supine fixation technique,and all patients were labeled with OPS.During the treatment,the patients were positioned according to the conventional method,and the patients were treated with cone beam computed tomography(CBCT)scanning and were moved to bed.The CBCT errors(control group)and OPS readings(observation group),including linear errors in X(left and right direction),Y(head and foot direction)and Z(ventral back direction),were recorded after moving to bed,and the two error results were analyzed and compared.Results:According to the standard of CBCT,the alignment errors of X,Y and Z were(1.95±1.16)mm,(3.87±1.67)mm and(1.71±1.03)mm,respectively.The corresponding OPS display errors in X,Y and Z directions were(0.63±0.56)mm,(0.31±0.49)mm and(0.32±0.22)mm,respectively.The OPS error was smaller than the traditional positioning error,and the difference was statistically significant(P<0.05).Conclusion:Compared with conventional laser alignment,OPS assisted positioning technique can significantly reduce the setting error of patients with thoracic and abdominal tumors during radiotherapy and improve the positioning accuracy during treatment.It has clinical application value for improving the accuracy of radioth erapy for patients with thoracic and abdominal tumors.

关 键 词：胸腹部肿瘤 体位固定 红外定位系统(OPS) 锥形束CT(CBCT) 

分 类 号：R730.55[医药卫生—肿瘤]