应用无机三氧化复合物对龋源性露髓的年轻恒牙进行部分活髓切断术治疗的临床疗效评价  

Evaluation of clinical efficacy of partial pulp cutting for caries exposed young permanent teeth with mineral trioxide aggregate.

作　　者：方溢云[1] 梁永棠[1] 于春梅[1] FANG Yi-yun;LIANG Yong-tang;YU Chun-mei(Department of Stomatology,Foshan First People's Hospital,Foshan Guangdong 528000,China.)

机构地区：[1]佛山市第一人民医院口腔科,广东佛山528000

出　　处：《临床和实验医学杂志》2022年第3期328-331,共4页Journal of Clinical and Experimental Medicine

基　　金：广东省佛山市科学技术局项目(编号:1920001001090)。

摘　　要：目的观察应用无机三氧化复合物(MTA)对龋源性露髓的年轻恒牙进行部分活髓切断术治疗的临床疗效。方法前瞻性选取2019年1月至2021年1月佛山市第一人民医院收治的80例年轻恒牙部分活髓切断术患者作为研究对象,按照随机数字表法分为观察组(MTA盖髓)与对照组(Dycal氢氧化钙)两组,每组40例。观察6个月,比较两组患者治疗相关指标,检测炎症因子水平的变化,随访手术前及手术后3个月、6个月牙根长度、治疗成功率、术后并发症发生情况。结果观察组治疗平均次数、平均周期为(3.05±0.64)次、(0.65±0.15)个月,均短于对照组[(3.05±0.64)次、(4.26±1.16)个月],差异均有统计学意义(P<0.05)。术前,两组患者各项炎症指标水平比较,差异无统计学意义(P>0.05);术后,观察组患者白细胞介素(IL)-1β、IL-6及肿瘤坏死因子α(TNF-α)水平为(13.25±2.54)、(1.02±0.25)、(2.37±0.44)μg/L,均明显低于对照组[(17.29±2.15)、(1.54±0.32)、(3.66±0.54)μg/L],差异均有统计学意义(P<0.05)。术前两组牙根长度比较,差异无统计学意义(P>0.05);术后3、6个月,观察组牙根长度为(15.45±1.63)、(16.12±0.42)mm,均明显长于对照组[(14.54±1.40)、(15.21±0.27)mm],差异均有统计学意义(P<0.05)。观察组术后6个月治疗成功率(95.0%)明显高于对照组(75.0%),差异有统计学意义(P<0.05);观察组并发症发生率(5.0%)明显低于对照组(20.0%),差异有统计学意义(P<0.05)。结论MTA应用于龋源性露髓年轻恒牙部分活髓切断术,有利于减轻炎症反应、改善牙根长度,治疗次数及周期少,效果可靠,并发症少,值得临床推广应用。Objective To investigate the clinical effect of partial pulp cutting for caries exposed young permanent teeth with mineral trioxide aggregate(MTA).Methods Eighty young permanent teeth partial pulpotomy patients admitted to the Foshan First People's Hospital from January 2019 to January 2021were prospectively selected as the research objects,and divided into observation group(MTA pulp capping)and the control group(Dycal calcium hydroxide)in the two groups according to the random number method,40 cases in each group.Six months of observation,treatment-related indicators of the two groups of patients were compared,changes in inflammatory factor levels were detected,the length of tooth root,the success rate of treatment and the incidence of postoperative complications were followed up before and 3 and 6 months after operation.Results The average number of times and average period of treatment in the observation group were(3.05±0.64)times and(0.65±0.15)months,which were shorter than those in the control group[(3.05±0.64)times,(4.26±1.16)months],and the differences were statistically significant(P<0.05).Before operation,there was no significant difference in the levels of inflammation indexes between the two groups of patients(P>0.05);after the operation,the levels of interleukin(IL)-1β,IL-6,tumor necrosis factor alpha(TNF-α)in the observation group were(13.25±2.54),(1.02±0.25),(2.37±0.44)μg/L,which were significantly lower than those in the control group[(17.29±2.15),(1.54±0.32),(3.66±0.54)μg/L],the differences were statistically significant(P<0.05).There was no significant difference in root length between the two groups before operation(P>0.05);3 and 6 months after operation,the root length of the observation group was(15.45±1.63)and(16.12±0.42)mm,which were significantly longer than those of the control group[(14.54±1.40),(15.21±0.27)mm],the difference was statistically significant(P<0.05).The treatment success rate(95.0%)of the observation group at 6 months after operation was significantly highe

关 键 词：年轻恒牙 龋源性露髓 无机三氧化复合物 部分活髓切断术 牙根长度 并发症 

分 类 号：R781.05[医药卫生—口腔医学]