胸腔镜下肺癌根治术治疗早期非小细胞肺癌的效果及对患者肺功能的影响  

Efficacy of thoracoscopic radical lung resection in the treatment of early nonsmall cell lung cancer and its effect on lung function

作　　者：冯光强[1] 陈涛 宋帅林 王鑫[1] FENG Guangqiang;CHEN Tao;SONG Shuailin;WANG Xin(Department of Cardiothoracic Surgery,the Fifth Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,He’nan,China)

机构地区：[1]郑州大学第五附属医院心胸外科,郑州450000

出　　处：《癌症进展》2022年第2期166-169,共4页Oncology Progress

摘　　要：目的研究胸腔镜下肺癌根治术治疗早期非小细胞肺癌(NSCLC)的效果及对患者肺功能的影响。方法将86例早期NSCLC患者根据手术方式不同分为观察组(完全胸腔镜下肺癌根治术)66例和对照组(小切口开胸肺癌根治术)20例,比较两组患者围手术期指标、术后并发症发生情况、术后1个月及术后6个月肺功能恢复情况以及随访1年后患者生活质量。结果观察组患者术中出血量明显少于对照组,引流管放置时间、住院时间均明显短于对照组,术后24 h视觉模拟评分法(VAS)评分明显低于对照组(P﹤0.01)。观察组患者并发症总发生率低于对照组(P﹤0.05)。术后6个月,观察组患者肺活量(VC)和第1秒用力呼气容积(FEV_(1))均高于术后1个月及对照组(P﹤0.05)。术后,两组患者生活质量各维度评分均高于术前,且观察组生活质量各维度评分均高于对照组(P﹤0.05)。结论胸腔镜下肺癌根治术能有效提高早期NSCLC的治疗效果,促进患者肺功能恢复,减少并发症的发生,改善患者术后生活质量。Objective To study the efficacy of thoracoscopic radical resection in the treatment of early non-small cell lung cancer(NSCLC)and its effect on lung function of patients.Method A total of 86 early NSCLC patients were divided into the observation group(n=66,treated with complete thoracoscopic radical resection)and control group(n=20,treated with small incision thoracotomy)according to the surgical methods;perioperative indicators,postoperative complications,pulmonary function recovery 1 month and 6 months after surgery and quality of life after 1 year of follow-up were compared.Result The intraoperative blood loss,drainage tube placement time,hospital stay and visual analogue scale(VAS)score at 24 h after surgery in the observation group were lower than those in the control group(P<0.01);the total incidence of complications in the observation group was significantly lower than that in the control group(P<0.05).Vital capacity(VC)and forced expiratory volume in one second(FEV_(1))at 6 months after surgery were higher than 1 month after surgery and control group(P<0.05);the dimensional scores of quality of life of two groups after surgery were higher than those before surgery,with higher scores in observation group than those in control group(P<0.05).Conclusion Thoracoscopic radical resection of lung cancer can effectively improve the therapeutic effect of early NSCLC,promote the recovery of lung function,reduce complications,and improve the postoperative quality of life.

关 键 词：非小细胞肺癌 胸腔镜 肺癌 肺功能 

分 类 号：R734.2[医药卫生—肿瘤]