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作 者:王冲[1] 张辉[1] 张爽[1] 宋桂德[1] 沈成凤[1] 王卓[1] 郑文龙[1] 王德征[1] WANG Chong;ZHANG Hui;ZHANG Shuang;SONG Gui-de;SHEN Cheng-feng;WANG Zhuo;ZHENG Wen-long;WANG De-zheng(Tianjin Center for Disease Control and Prevention,Tianjin 300011,China)
出 处:《中国肿瘤》2022年第2期127-131,共5页China Cancer
基 金:天津市卫生高层次人才选拔培养项目(津人才[2018]19号)。
摘 要:[目的]了解天津市居民1999—2018年骨肿瘤死亡率及其变化趋势。[方法]采用1999—2018年天津市疾病预防控制中心覆盖全市人群的全死因监测数据,计算骨肿瘤的死亡数、粗死亡率及标化死亡率,采用Joinpoint回归分析骨肿瘤死亡率分年龄组、性别、城乡的变化趋势。[结果]1999—2018年天津市居民骨肿瘤死亡4257例,世标死亡率从1.63/10万下降至0.90/10万,呈下降趋势(APC=-2.50%,P<0.05)。<35岁、45~54岁、55~64岁和65岁及以上年龄组骨肿瘤死亡率均呈下降趋势(P均<0.05);男性和女性世标死亡率均呈下降趋势(P<0.05),女性下降速度更快(男性APC=-2.16%,女性APC=-2.90%),且女性死亡中位年龄有升高趋势(P<0.05);分城乡分析显示城市地区粗死亡率和世标死亡率均呈下降趋势(P<0.05),农村居民的骨肿瘤粗死亡率呈上升趋势(P<0.05)。骨肿瘤死亡率随着年龄的增长而上升,农村地区骨肿瘤死亡率明显高于城市地区。[结论]1999—2018年天津市居民骨肿瘤世标死亡率明显下降,男性、女性、城市世标死亡率均呈现下降趋势,女性下降更快,且死亡中位年龄后移,但农村居民的骨肿瘤粗死亡率呈升高趋势,提示应关注农村地区骨肿瘤死亡风险,采取针对性的防治措施,减少骨肿瘤死亡。[Purpose]To analyze the trends and distribution of bone cancer mortality from 1999 to2018 in Tianjin municipality.[Methods]Mortality data of bone cancer from 1999 to 2018 were obtained from Tianjin population based mortality surveillance system maintained by the Tianjin Center for Disease Control and Prevention(CDC).The number of deaths,crude mortality rate and age-standardized mortality rate by world standard(Seg’s)population(ASMRW)of bone cancer were calculated.The annual percentage of change(APC)of mortality was analyzed with Joinpoint regression by age,gender and areas(urban,rural).[Results]Totally 4257 death cases of bone cancer were observed in Tianjin from 1999 to 2018.The ASMRW of bone cancer decreased from1.63/105 in 1999 to 0.90/105 to 2018(APC=-2.50%,P<0.05).The mortality of bone cancer showed a downward trend(all P<0.05)in the age groups<35,45~54,55~64 and 65 years and over.The ASMRW of bone cancer were decreased in both gender(P<0.05);ASMRW for women was declined more than that for men,and the median age of death increased for women(P<0.05).Both the crude mortality rate and ASMRW of bone cancer decreased in urban areas(P<0.05);while the crude mortality rate of bone cancer in rural areas increased(P<0.05).The crude mortality rate of bone increased with age,and the crude mortality in rural areas was significantly higher than that in urban areas.[Conclusion]Bone cancer mortality shows a decreasing trend from 1999 to 2018 in Tianjin,however,the crude mortality rate of bone cancer increased in rural areas,suggesting the targeted prevention and control measures are necessary.
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