术前MRI对垂体腺瘤手术预后价值研究  

Investigate the Prognostic Value of Preoperative MRI for Pituitary Adenoma

作　　者：王苏平 肖瑾[2] 赵雪梅[1] 钱银锋[1] WANG Su-ping;XIAO Jin;ZHAO Xue-mei;QIAN Yin-feng(Department of Radiology,the First Affiliated Hospital of Anhui Medical University,Hefei 230022,Anhui,China;Department of Neurosurgery,the First Affiliated Hospital of Anhui Medical University,Hefei 230022,Anhui,China)

机构地区：[1]安徽医科大学第一附属医院放射科,安徽合肥230022 [2]安徽医科大学第一附属医院神经外科,安徽合肥230022

出　　处：《医学信息》2022年第5期174-177,共4页Journal of Medical Information

基　　金：安徽省学术和技术带头人后备人选科研活动经费资助项目(编号:2020H232);安徽医科大学校级课题(编号:2020xkj184)。

摘　　要：目的探讨术前MRI预测功能性垂体瘤患者手术肿瘤切除及生化缓解情况的价值。方法回顾性分析2016年12月-2020年10月我院75例功能性垂体瘤患者手术前后MRI影像及临床资料,分析垂体瘤术后切除及术后缓解间肿瘤直径、MRI信号、囊变、出血、Konsp分级情况。结果75例患者中垂体微腺瘤9例、垂体大腺瘤63例、垂体巨大腺瘤3例;促肾上腺皮质激素腺瘤7例,生长激素腺瘤24例,泌乳素腺瘤28例,促性激素腺瘤16例;有52例(69.33%)达到完全切除及激素缓解。完全切除与未完全切除和完全缓解与未完全缓解间肿瘤直径、T1+C中轻度强化和明显强化、Knosp分级比较,差异有统计学意义(P<0.05);完全切除与未完全切除和完全缓解与未完全缓解间T1WI、T2WI、T1+C中中度强化、囊变、出血比较,差异无统计学意义(P>0.05)。结论功能性垂体腺瘤患者术前MRI检查对术后肿瘤切除及缓解程度具有一定的预测价值。Objective To investigate the value of preoperative MRI in predicting tumor resection and biochemical remission in patients with functional pituitary tumors.Methods The MRI images and clinical data of 75 patients with functional pituitary tumors in our hospital from December 2016 to October 2020 were retrospectively analyzed.The tumor diameter,MRI signal,cystic change,bleeding and Konsp classification between postoperative resection and postoperative remission of pituitary tumors were analyzed.Results Among the 75 patients,there were 9 cases of pituitary microadenoma,63 cases of pituitary macroadenoma and 3 cases of pituitary macroadenoma;7 cases of adrenal cortical adenoma,24 cases of growth hormone adenoma,28 cases of prolactin adenoma and 16 cases of sex hormone adenoma;52 cases(69.33%)achieved complete resection and hormone remission.There were statistically significant differences in tumor diameter,mild and obvious enhancement in T1+C,and Knosp grading between complete resection and incomplete resection or between complete remission and incomplete remission(<0.05);there was no significant difference in T1WI,T2WI,moderate enhancement in T1+C,cystic degeneration and bleeding between complete resection and incomplete resection or between complete remission and incomplete remission(>0.05).Conclusion Preoperative MRI examination in patients with functional pituitary adenoma has certain predictive value for postoperative tumor resection and remission.

关 键 词：垂体腺瘤 磁共振成像 生长激素腺瘤 泌乳素腺瘤 

分 类 号：R736.4[医药卫生—肿瘤]