FibroTouch定量评估某体检人群脂肪肝和显著肝纤维化的应用价值  

The Application Value of FibroTouch in Quantitatively Evaluating Fatty Liver and Obvious Hepatic Fibrosis in a Certain Physical Examination Population

作　　者：季圆 陆维[1] 茅溢恒 顾炜[1] 侯琳琳[1] Ji Yuan;Lu Wei;Mao Yiheng;Gu Wei;Hou Linlin(Wuxi People's Hospital,Wuxi Jiangsu 214023,China)

机构地区：[1]无锡市人民医院,江苏无锡214023

出　　处：《医疗装备》2022年第5期126-129,共4页Medical Equipment

摘　　要：目的探讨FibroTouch定量评估某体检人群脂肪肝和显著肝纤维化的应用价值。方法选择2020年6月至2021年11月于无锡市人民医院健康管理中心行FibroTouch检测的538名体检者,将499名检测成功且信息完整的体检者纳入本研究,收集体检者的性别、年龄、身高、体质量等一般资料,采用FibroTouch检测超声衰减参数(UAP)和肝脏弹性值(LSM),统计499名体检者中脂肪肝及显著肝纤维化的检出情况,比较不同性别和体质量指数(BMI)体检者中脂肪肝及显著肝纤维化的检出率。结果499名体检者中,314名(62.93%)存在不同程度的脂肪肝,其中,轻度108名(21.64%)、中度129名(25.85%)、重度77名(15.43%);26名(5.21%)存在显著肝纤维化。脂肪肝在男性中的检出率高于女性,差异有统计学意义(χ^(2)=42.507,P<0.0001);显著肝纤维化在男性与女性中的检出率比较,差异无统计学意义(χ^(2)=0.098,P=0.754)。在体质量过低、体质量正常、超重和肥胖体检者中,脂肪肝的检出率分别为0.00%、36.82%、77.52%和98.61%,差异有统计学意义(χ^(2)=131.527,P<0.0001);在体质量过低、体质量正常、超重和肥胖体检者中,显著肝纤维化的检出率分别为0.00%、3.98%、5.05%和9.72%,差异无统计学意义(χ^(2)=4.035,P=0.258)。结论基于Fibro Touch检测的某体检人群脂肪肝的检出率较高,且在男性中的检出率高于女性,同时,脂肪肝及显著肝纤维化的检出率随着体检者BMI的增加而逐渐升高,应加强对BMI较高者的健康管理。Objective The application value of FibroTouch in quantitatively evaluating fatty liver and obvious hepatic fibrosis in a certain physical examination population was explored.Methods From June 2020 to November 2021,in the Health Management Center of Wuxi People’s Hospital,all 538 physical examiners who participated in the FibroTouch examination were selected.Among them,499 physical examiners whose examination were successful and meanwhile the medical information was intact were included in this study.The clinical data such as gender,age,height and weight was collected and FibroTouch was used to detect ultrasound attenuation parameter(UAP)and liver stiffness measurement(LSM).The detection results of fatty liver and obvious hepatic fibrosis of 499 physical examiners were counted,and then the detection rates of fatty liver and obvious hepatic fibrosis of physical examiners with different gender and body mass index(BMI)were compared.Results Among the 499 physical examiners,314(62.93%)had different degrees of fatty liver,of which 108(21.64%)were mild,129(25.85%)were moderate,and 77(15.43%)were severe;26(5.21%)were detected with obvious hepatic fibrosis.The detection rate of fatty liver in men was higher than that in women,and the difference was statistically significant(χ^(2)=42.507,P<0.0001);There was no significant difference in the detection rate of obvious hepatic fibrosis between men and women(χ^(2)=0.098,P=0.754).Among the underweight,normal,overweight and obese subjects,the detection rates of fatty liver were 0.00%,36.82%,77.52%and 98.61%,and the difference was statistically significant(χ^(2)=131.527,P<0.0001);In the underweight,normal,overweight and obese subjects,the detection rates of obvious hepatic fibrosis were 0.00%,3.98%,5.05%,and 9.72%,and the difference was not statistically significant(χ^(2)=4.035,P=0.258).Conclusions The detection rate of fatty liver in a certain physical examination population based on FibroTouch examination was relatively high and it was higher among men than women.Meanwhile

关 键 词：FibroTouch检测 超声衰减参数 肝脏弹性值 脂肪肝 显著肝纤维化 检出率 

分 类 号：R575[医药卫生—消化系统]