成人缺铁性贫血患者消化道肿瘤的危险因素分析  

Analysis of risk factors of digestive tract tumors in adult patients with iron deficiency anemia

作　　者：沈晶晶[1] 徐永灿 陈叶龙[1] SHEN Jingjing;XU Yongcan;CHEN Yelong(Department of Hematology,Huzhou Central Hospital,Affiliated Hospital of Huzhou Normal University,Huzhou 313000,China)

机构地区：[1]湖州市中心医院湖州师范学院附属中心医院血液科,浙江湖州313000

出　　处：《中国现代医生》2022年第5期105-108,共4页China Modern Doctor

基　　金：国家自然科学基金资助项目(81802309)。

摘　　要：目的探讨成人缺铁性贫血(IDA)患者中消化道肿瘤的患病率及危险因素。方法回顾性分析2016年1月至2019年12月湖州市中心医院血液科就诊的初治IDA患者154例,分为消化道肿瘤组和良性病变组,比较两组临床特征,并通过多因素logistic回归模型分析危险因素。结果消化道肿瘤组患者的年龄、铁蛋白、血红蛋白(Hb)、癌胚抗原(CEA)和乳酸脱氢酶(LDH)与良性病变组比较,差异有统计学意义(P<0.05),多因素分析显示年龄、CEA是缺铁性贫血患者消化道肿瘤的影响因素(P<0.05)。结论消化道肿瘤是IDA的重要原因,而高龄及CEA增高是缺铁性贫血患者消化道肿瘤的危险因素,在临床中需要密切关注。Objective To investigate the prevalence and risk factors of digestive tract tumors in adult patients with iron deficiency anemia(IDA).Methods A total of 154 newly diagnosed patients with IDA admitted to the department of hematology of Department of Hematology,Huzhou Central Hospital,from January 2016 to December 2019 were retrospectively analyzed.And they were divided into the digestive tract tumor group and the benign lesion group.The clinical features of the two groups were compared,and the risk factors were analyzed by multivariate logistic regression model.Results There were statistically significant differences in patient’s age,ferritin,hemoglobin(HB),carcinoembryonic antigen(CEA)and lactate dehydrogenase(LDH)between the digestive tract tumor group and the benign lesion group(P<0.05).Multivariate analysis showed that age and CEA were influence factors of digestive tract tumor patients(P<0.05).Conclusion Digestive tract tumor is an important cause of IDA,and advanced age and increased CEA are risk factors of digestive tract tumor in patients with iron deficiency anemia,which need close attention in clinical practice.

关 键 词：消化道肿瘤 缺铁性贫血 癌胚抗原 血红蛋白 

分 类 号：R735[医药卫生—肿瘤]