NLR与CRP对急性甘油三酯血症性胰腺炎病情严重程度的预测价值  

The predictive value of NLR and CRP in the severity of acute hypertriglyceridemia pancreatitis

作　　者：薛祥 谢东辉[1] 黄昌保 汪利宗[1] XUE Xiang;XIE Donghui;HUANG Changbao;WANG Lizong(Department of Emergency,Yijishan Hospital,Wannan Medical College,Wuhu,Anhui,China,241000)

机构地区：[1]皖南医学院弋矶山医院急诊科,安徽芜湖241000

出　　处：《分子诊断与治疗杂志》2022年第2期249-252,257,共5页Journal of Molecular Diagnostics and Therapy

基　　金：弋矶山医院引进人才专项科研基金(YR201906)。

摘　　要：目的探讨NLR与CRP对急性高甘油三脂血症性胰腺炎(AHTGP)病情严重程度的预测价值。方法选取2020年1月至2021年9月皖南医学院弋矶山医院急诊内科收治的94例AHTGP患者,依据其病情严重程度分为MAP组47例,MSAP组30例,SAP组17例。分析AHTGP患者病情严重程度的影响因素及NLR与CRP对其预测价值。结果APACHEⅡ评分、MCTSI评分、TC、TG、CRP、NLR、PLR增高均为AHTGP患者病情严重的危险因素(P<0.05),血清钙增高为AHTGP患者病情严重的保护因素(P<0.05);ROC曲线分析显示,NLR、CRP及两项联合预测患者AHTGP患者病情严重程度AUC分别为0.865、0.872、0.904,可知,两项联合指标预测价值高于单项指标,其敏感度、特异度为1.000、0.753。结论NLR与CRP为AHTGP病情严重程度的影响因素,对其具有一定预测价值。Objective To explore the predictive value of NLR and CRP in the severity of acute hypertriglycerid pancreatitis(AHTGP).Methods A total of 94 AHTGP patients admitted to the emergency department of Yijishan Hospital,Wannan Medical College from January 2020 to September 2021 were selected and divided into the MAP group(n=47),the MSAP group(n=30)and the SAP group(n=17)according to their severity.The influencing factors of disease severity in AHTGP patients and the predictive value of NLR and CRP were analyzed.Results APACHE II score,MCTSI score,increased TC,TG,CRP,NLR,and PLR were all risk factors for severe disease in patients with AHTGP(P<0.05).Increased serum calcium was a protective factor for severe disease in AHTGP patients(P<0.05).ROC curve analysis showed that the AUC of NLR,CRP and the two combined to predict the severity of AHTGP patients were 0.865,0.872,and 0.904,respectively.The predictive value of the two combined indicators was higher than that of the single indicator,and their sensitivity and specificity were 1.000 and 0.753.Conclusion NLR and CRP are the influencing factors of the severity of AHTGP,and have certain predictive value.

关 键 词：NLR CRP 急性高甘油三脂血症性胰腺炎 预测价值 

分 类 号：R576[医药卫生—消化系统]